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• W2003222308 abstract "This study reports that peripheral administration of Nerve Growth Factor antibodies (ANA) affects behavior in aged female CD-1 mice. ANA increased the propensity of mice to stay and perform behaviors in the anxiogenic open arms of the maze, lowered pain sensitivity and reduced behavioral flexibility in a Morris water maze task, also reducing ChAT immunoreactivity in the basal forebrain. These findings support the hypothesis that topical eye application can represent an alternative route for delivering biologically active compounds into the brain allowing studying the role of NGF on brain cell function." @default.
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• W2003222308 date "2010-07-01" @default.
• W2003222308 modified "2023-10-17" @default.
• W2003222308 title "Conjunctivally administered NGF antibody reduces pain sensitivity and anxiety-like behavioral responses in aged female mice" @default.
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• W2003222308 doi "https://doi.org/10.1016/j.bbr.2010.02.037" @default.
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