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• W2003227439 abstract "Lymphocytes bearing the CD8 marker were shown to suppress replication of human immunodeficiency virus (HIV) in peripheral blood mononuclear cells. The effect was dose-dependent and most apparent with autologous lymphocytes; it did not appear to be mediated by a cytotoxic response. This suppression of HIV replication could be demonstrated by the addition of CD8+ cells at the initiation of virus production as well as after several weeks of virus replication by cultured cells. The observations suggest a potential approach to therapy in which autologous CD8 lymphocytes could be administered to individuals to inhibit HIV replication and perhaps progression of disease." @default.
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• W2003227439 date "1986-12-19" @default.
• W2003227439 modified "2023-10-18" @default.
• W2003227439 title "CD8⁺Lymphocytes Can Control HIV Infection in Vitro by Suppressing Virus Replication" @default.
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• W2003227439 doi "https://doi.org/10.1126/science.2431484" @default.
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