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• W2003227842 abstract "The PPARs are integral parts of the RXR-dependent signaling networks. Many other nuclear receptor subfamily 1 members also require RXR as their obligatory heterodimerization partner and they are often co-expressed in any given tissue. Therefore, the PPARs often complete with other RXR-dependent nuclear receptors and this competition has important biological implications. Thorough understanding of this cross-talk at the molecular level is crucial to determine the detailed functional roles of the PPARs. At the level of DNA binding, most RXR heterodimers bind selectively to the well-known DR1 to 5 DNA response elements. As a result, many heterodimers share the same DR element and must complete with each other for DNA binding. At the level of heterodimerization, the partners of RXR share the same RXR dimerization interface. As a result, individual nuclear receptors must complete with each other for RXR to form functional heterodimers. Cross-talk through DNA binding and RXR heterodimerization present challenges to the study of these nuclear receptors that cannot be adequately addressed by current experimental approaches. Novel tools, such as engineered nuclear receptors with altered dimerization properties, are currently being developed. These tools will enable future studies to dissect specific RXR heterodimers and their signaling pathways." @default.
• W2003227842 created "2016-06-24" @default.
• W2003227842 creator A5018283449 @default.
• W2003227842 creator A5078283064 @default.
• W2003227842 date "2009-01-01" @default.
• W2003227842 modified "2023-10-16" @default.
• W2003227842 title "Cross-Talk between PPARs and the Partners of RXR: A Molecular Perspective" @default.
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• W2003227842 cites W1622461349 @default.
• W2003227842 cites W1814235153 @default.
• W2003227842 cites W1968703258 @default.
• W2003227842 cites W1970329407 @default.
• W2003227842 cites W1970474244 @default.
• W2003227842 cites W1979201752 @default.
• W2003227842 cites W1979761686 @default.
• W2003227842 cites W1980222251 @default.
• W2003227842 cites W1985865142 @default.
• W2003227842 cites W1987269203 @default.
• W2003227842 cites W1991293484 @default.
• W2003227842 cites W1992806705 @default.
• W2003227842 cites W1993132549 @default.
• W2003227842 cites W1995754186 @default.
• W2003227842 cites W2001260034 @default.
• W2003227842 cites W2002032260 @default.
• W2003227842 cites W2004352153 @default.
• W2003227842 cites W2005051319 @default.
• W2003227842 cites W2006602286 @default.
• W2003227842 cites W2011467252 @default.
• W2003227842 cites W2011982810 @default.
• W2003227842 cites W2017918116 @default.
• W2003227842 cites W2021857647 @default.
• W2003227842 cites W2022891913 @default.
• W2003227842 cites W2026140820 @default.
• W2003227842 cites W2031147021 @default.
• W2003227842 cites W2032505867 @default.
• W2003227842 cites W2035815778 @default.
• W2003227842 cites W2036084641 @default.
• W2003227842 cites W2040872150 @default.
• W2003227842 cites W2042901562 @default.
• W2003227842 cites W2059388722 @default.
• W2003227842 cites W2059415631 @default.
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• W2003227842 cites W2065485581 @default.
• W2003227842 cites W2066092624 @default.
• W2003227842 cites W2066837860 @default.
• W2003227842 cites W2070136069 @default.
• W2003227842 cites W2071802200 @default.
• W2003227842 cites W2075232957 @default.
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• W2003227842 cites W2147596285 @default.
• W2003227842 cites W2147627625 @default.
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• W2003227842 cites W2399414035 @default.
• W2003227842 cites W4234609843 @default.
• W2003227842 cites W4235010327 @default.
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• W2003227842 doi "https://doi.org/10.1155/2009/925309" @default.
• W2003227842 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2801013" @default.
• W2003227842 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20052392" @default.
• W2003227842 hasPublicationYear "2009" @default.
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