FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003236441> ?p ?o ?g. }

• W2003236441 endingPage "511" @default.
• W2003236441 startingPage "503" @default.
• W2003236441 abstract "Long QT syndrome (LQTS) is a congenital disorder accompanied by a high incidence of sudden cardiac death. beta-Adrenergic blockade is the therapy of choice, and it is successful in 75-80% of patients. For those in whom cardiac events (syncope or cardiac arrest) are not prevented by beta-blockade, experimental studies suggest that left cardiac sympathetic denervation (LCSD) may be useful.We identified 85 LQTS patients worldwide who underwent LCSD, and we provide here the first large-scale evaluation of its efficacy. The time interval between the first cardiac event and LCSD and the follow-up period after LCSD were similar (5.6 +/- 6.1 versus 5.9 +/- 5.7 years). The mean age of the patients at surgery was 20 +/- 13 years. LCSD was followed by highly significant (p less than 0.0001) decreases in the number of patients with cardiac events (from 99% to 45%), in the number of cardiac events per patient (from 22 +/- 32 to 1 +/- 3), and in the number of patients with five or more cardiac events (from 71% to 10%). There were seven sudden deaths (8%), and the 5-year survival rate was 94%. The marked reduction in the incidence of tachyarrhythmic syncope suggests that LCSD has also reduced the risk for sudden death in this high-risk population.The present findings demonstrate that for LQTS patients who continue with syncope or cardiac arrest despite the use of beta-blockers, LCSD is a very effective therapy." @default.
• W2003236441 created "2016-06-24" @default.
• W2003236441 creator A5013224321 @default.
• W2003236441 creator A5015949505 @default.
• W2003236441 creator A5049150501 @default.
• W2003236441 creator A5076034611 @default.
• W2003236441 creator A5076422519 @default.
• W2003236441 creator A5081803323 @default.
• W2003236441 date "1991-08-01" @default.
• W2003236441 modified "2023-10-12" @default.
• W2003236441 title "Left cardiac sympathetic denervation in the therapy of congenital long QT syndrome. A worldwide report." @default.
• W2003236441 cites W1981098216 @default.
• W2003236441 cites W1986926972 @default.
• W2003236441 cites W1987568857 @default.
• W2003236441 cites W1988318482 @default.
• W2003236441 cites W1995033447 @default.
• W2003236441 cites W2001160633 @default.
• W2003236441 cites W2001715969 @default.
• W2003236441 cites W2005240974 @default.
• W2003236441 cites W2012808111 @default.
• W2003236441 cites W2013866684 @default.
• W2003236441 cites W2014530124 @default.
• W2003236441 cites W2014696415 @default.
• W2003236441 cites W2035961334 @default.
• W2003236441 cites W2044526535 @default.
• W2003236441 cites W2052593384 @default.
• W2003236441 cites W2059336887 @default.
• W2003236441 cites W2077540740 @default.
• W2003236441 cites W2106147539 @default.
• W2003236441 cites W2111121698 @default.
• W2003236441 cites W2132160350 @default.
• W2003236441 cites W2150000105 @default.
• W2003236441 cites W2156381642 @default.
• W2003236441 cites W2162979922 @default.
• W2003236441 cites W2166770783 @default.
• W2003236441 cites W2254662319 @default.
• W2003236441 cites W2330406605 @default.
• W2003236441 cites W2398189163 @default.
• W2003236441 cites W2399431059 @default.
• W2003236441 cites W608615961 @default.
• W2003236441 doi "https://doi.org/10.1161/01.cir.84.2.503" @default.
• W2003236441 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1860195" @default.
• W2003236441 hasPublicationYear "1991" @default.
• W2003236441 type Work @default.
• W2003236441 sameAs 2003236441 @default.
• W2003236441 citedByCount "316" @default.
• W2003236441 countsByYear W20032364412012 @default.
• W2003236441 countsByYear W20032364412013 @default.
• W2003236441 countsByYear W20032364412014 @default.
• W2003236441 countsByYear W20032364412015 @default.
• W2003236441 countsByYear W20032364412016 @default.
• W2003236441 countsByYear W20032364412017 @default.
• W2003236441 countsByYear W20032364412018 @default.
• W2003236441 countsByYear W20032364412019 @default.
• W2003236441 countsByYear W20032364412020 @default.
• W2003236441 countsByYear W20032364412021 @default.
• W2003236441 countsByYear W20032364412022 @default.
• W2003236441 countsByYear W20032364412023 @default.
• W2003236441 crossrefType "journal-article" @default.
• W2003236441 hasAuthorship W2003236441A5013224321 @default.
• W2003236441 hasAuthorship W2003236441A5015949505 @default.
• W2003236441 hasAuthorship W2003236441A5049150501 @default.
• W2003236441 hasAuthorship W2003236441A5076034611 @default.
• W2003236441 hasAuthorship W2003236441A5076422519 @default.
• W2003236441 hasAuthorship W2003236441A5081803323 @default.
• W2003236441 hasBestOaLocation W20032364411 @default.
• W2003236441 hasConcept C118441451 @default.
• W2003236441 hasConcept C120665830 @default.
• W2003236441 hasConcept C121332964 @default.
• W2003236441 hasConcept C126322002 @default.
• W2003236441 hasConcept C164705383 @default.
• W2003236441 hasConcept C2775935837 @default.
• W2003236441 hasConcept C2776805190 @default.
• W2003236441 hasConcept C2779703243 @default.
• W2003236441 hasConcept C2908647359 @default.
• W2003236441 hasConcept C2909070644 @default.
• W2003236441 hasConcept C42219234 @default.
• W2003236441 hasConcept C61511704 @default.
• W2003236441 hasConcept C71924100 @default.
• W2003236441 hasConcept C99454951 @default.
• W2003236441 hasConceptScore W2003236441C118441451 @default.
• W2003236441 hasConceptScore W2003236441C120665830 @default.
• W2003236441 hasConceptScore W2003236441C121332964 @default.
• W2003236441 hasConceptScore W2003236441C126322002 @default.
• W2003236441 hasConceptScore W2003236441C164705383 @default.
• W2003236441 hasConceptScore W2003236441C2775935837 @default.
• W2003236441 hasConceptScore W2003236441C2776805190 @default.
• W2003236441 hasConceptScore W2003236441C2779703243 @default.
• W2003236441 hasConceptScore W2003236441C2908647359 @default.
• W2003236441 hasConceptScore W2003236441C2909070644 @default.
• W2003236441 hasConceptScore W2003236441C42219234 @default.
• W2003236441 hasConceptScore W2003236441C61511704 @default.
• W2003236441 hasConceptScore W2003236441C71924100 @default.
• W2003236441 hasConceptScore W2003236441C99454951 @default.
• W2003236441 hasIssue "2" @default.
• W2003236441 hasLocation W20032364411 @default.
• W2003236441 hasLocation W20032364412 @default.
• W2003236441 hasOpenAccess W2003236441 @default.

• next