FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003239719> ?p ?o ?g. }

• W2003239719 endingPage "369" @default.
• W2003239719 startingPage "361" @default.
• W2003239719 abstract "The metabolism of apolipoproteins (apo) (a) and B-100 within plasma lipoprotein (a) [Lp(a)] was examined in the fed state in 23 subjects aged 41 to 79 years who received a primed-constant infusion of [5,5,5-2H3] leucine over 15 hours. Lipoprotein (a) was isolated from the whole plasma using a lectin affinity-based method. Apolipoprotein (a) and apoB-100 were separated by gel electrophoresis, and tracer enrichment of each apolipoprotein was measured using gas chromatography/mass spectrometry. Data were fit to a multicompartmental model to determine fractional catabolic rates (FCRs) and secretion rates (SRs). The FCRs of apo(a) and apoB-100 (mean +/- SEM) within plasma Lp(a) were significantly different (0.220 +/- 0.030 pool/d and 0.416 +/- 0.040 pool/d, respectively; P < .001). Apolipoprotein (a) SR (0.50 +/- 0.08 mg/[kg per d]) was significantly lower than that of apoB-100 SR (1.53 +/- 0.22 mg/[kg per d]; P < .001) of Lp(a). Plasma concentrations of Lp(a) were correlated significantly with both apo(a) SR and apoB-100 SR (r = 0.837 and r = 0.789, respectively; P < .001) and negatively with apo(a) FCR and Lp(a) apoB-100 FCR (r = -0.547 and r = -0.717, respectively; P < .01). These data implicate different metabolic fates for apo(a) and apoB-100 within Lp(a) in the fed state. We therefore hypothesize that apo(a) does not remain covalently linked to a single apoB-100 lipoprotein but that it rather reassociates at least once with another apoB-100 particle, probably newly synthesized, during its plasma metabolism." @default.
• W2003239719 created "2016-06-24" @default.
• W2003239719 creator A5016419487 @default.
• W2003239719 creator A5020765050 @default.
• W2003239719 creator A5055281543 @default.
• W2003239719 creator A5058290335 @default.
• W2003239719 creator A5061455831 @default.
• W2003239719 creator A5064285461 @default.
• W2003239719 creator A5067464347 @default.
• W2003239719 creator A5074343044 @default.
• W2003239719 creator A5081502914 @default.
• W2003239719 creator A5081810419 @default.
• W2003239719 creator A5087239434 @default.
• W2003239719 date "2005-03-01" @default.
• W2003239719 modified "2023-10-14" @default.
• W2003239719 title "The metabolism of apolipoproteins (a) and B-100 within plasma lipoprotein (a) in human beings" @default.
• W2003239719 cites W1669661359 @default.
• W2003239719 cites W1848836653 @default.
• W2003239719 cites W1860487341 @default.
• W2003239719 cites W1876370444 @default.
• W2003239719 cites W1902354643 @default.
• W2003239719 cites W1923408704 @default.
• W2003239719 cites W1929632323 @default.
• W2003239719 cites W1964777313 @default.
• W2003239719 cites W1975168532 @default.
• W2003239719 cites W1975678175 @default.
• W2003239719 cites W1977684642 @default.
• W2003239719 cites W1983762801 @default.
• W2003239719 cites W1987023197 @default.
• W2003239719 cites W1998030902 @default.
• W2003239719 cites W2001255603 @default.
• W2003239719 cites W2015664419 @default.
• W2003239719 cites W2016026919 @default.
• W2003239719 cites W2027406869 @default.
• W2003239719 cites W2029076884 @default.
• W2003239719 cites W2053607106 @default.
• W2003239719 cites W2055776201 @default.
• W2003239719 cites W2056546387 @default.
• W2003239719 cites W2062899313 @default.
• W2003239719 cites W2067318301 @default.
• W2003239719 cites W2068733672 @default.
• W2003239719 cites W2071679006 @default.
• W2003239719 cites W2074767397 @default.
• W2003239719 cites W2081395015 @default.
• W2003239719 cites W2092304672 @default.
• W2003239719 cites W2092506349 @default.
• W2003239719 cites W2093535758 @default.
• W2003239719 cites W2117245915 @default.
• W2003239719 cites W2117264692 @default.
• W2003239719 cites W2121966013 @default.
• W2003239719 cites W2125271508 @default.
• W2003239719 cites W2130483103 @default.
• W2003239719 cites W2133499309 @default.
• W2003239719 cites W2135503869 @default.
• W2003239719 cites W2136307469 @default.
• W2003239719 cites W2154251179 @default.
• W2003239719 cites W2167033150 @default.
• W2003239719 cites W2169761191 @default.
• W2003239719 cites W2344529588 @default.
• W2003239719 cites W2368946932 @default.
• W2003239719 cites W4236170856 @default.
• W2003239719 cites W4248613067 @default.
• W2003239719 doi "https://doi.org/10.1016/j.metabol.2004.10.001" @default.
• W2003239719 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15736114" @default.
• W2003239719 hasPublicationYear "2005" @default.
• W2003239719 type Work @default.
• W2003239719 sameAs 2003239719 @default.
• W2003239719 citedByCount "60" @default.
• W2003239719 countsByYear W20032397192012 @default.
• W2003239719 countsByYear W20032397192013 @default.
• W2003239719 countsByYear W20032397192014 @default.
• W2003239719 countsByYear W20032397192015 @default.
• W2003239719 countsByYear W20032397192016 @default.
• W2003239719 countsByYear W20032397192017 @default.
• W2003239719 countsByYear W20032397192018 @default.
• W2003239719 countsByYear W20032397192019 @default.
• W2003239719 countsByYear W20032397192020 @default.
• W2003239719 countsByYear W20032397192022 @default.
• W2003239719 countsByYear W20032397192023 @default.
• W2003239719 crossrefType "journal-article" @default.
• W2003239719 hasAuthorship W2003239719A5016419487 @default.
• W2003239719 hasAuthorship W2003239719A5020765050 @default.
• W2003239719 hasAuthorship W2003239719A5055281543 @default.
• W2003239719 hasAuthorship W2003239719A5058290335 @default.
• W2003239719 hasAuthorship W2003239719A5061455831 @default.
• W2003239719 hasAuthorship W2003239719A5064285461 @default.
• W2003239719 hasAuthorship W2003239719A5067464347 @default.
• W2003239719 hasAuthorship W2003239719A5074343044 @default.
• W2003239719 hasAuthorship W2003239719A5081502914 @default.
• W2003239719 hasAuthorship W2003239719A5081810419 @default.
• W2003239719 hasAuthorship W2003239719A5087239434 @default.
• W2003239719 hasConcept C126322002 @default.
• W2003239719 hasConcept C134018914 @default.
• W2003239719 hasConcept C185592680 @default.
• W2003239719 hasConcept C2776104379 @default.
• W2003239719 hasConcept C2778163477 @default.
• W2003239719 hasConcept C2780072125 @default.
• W2003239719 hasConcept C55493867 @default.

• next