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- W2003241496 abstract "A series of water-soluble dicationic dibenzotetraaza[14]annulenes have been prepared in order to examine their interactions with nucleic acids. Pendant water-solubilizing N-pyridinium, 4,4′-bipyridinium and N-methyl pyridinium moieties have been attached to the central core via linkers generated by direct N-alkylations and ester creating couplings, respectively. The crystal structures of derivatives equipped with 3-(N-pyridinium-1-yl)propyl and 3-(4,4′-bipyridinium-1-yl)propyl substituents have been determined. Interactions with ct-DNA have been studied and evidenced by means of spectrophotometric titrations with Scatchard analysis and thermal denaturation experiments." @default.
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- W2003241496 date "2006-09-01" @default.
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- W2003241496 title "Synthesis, crystal structures and the preliminary evaluation of the new dibenzotetraaza[14]annulene-based DNA/RNA binding agents" @default.
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- W2003241496 doi "https://doi.org/10.1016/j.tet.2006.07.045" @default.
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