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- W2003244414 abstract "In the current study we investigated the role of dopamine in attentional and socio-emotional functioning by examining effects of withdrawing dopaminergic medication in patients with Parkinson's disease (PD). Patients on medication exhibited abnormal betting strategies on a task of decision-making, reflecting impulsive behaviour and/or delay aversion, whilst the same patients off medication exhibited abnormally increased switch costs when switching between two tasks, reflecting attentional inflexibility. Hence, these data replicate and extend previous findings that dopaminergic medication improves or impairs cognitive performance depending on the nature of the task and the basal level of dopamine function in underlying cortico-striatal circuitry." @default.
- W2003244414 created "2016-06-24" @default.
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- W2003244414 date "2003-01-01" @default.
- W2003244414 modified "2023-09-30" @default.
- W2003244414 title "l-Dopa medication remediates cognitive inflexibility, but increases impulsivity in patients with Parkinson’s disease" @default.
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- W2003244414 doi "https://doi.org/10.1016/s0028-3932(03)00117-9" @default.
- W2003244414 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12849761" @default.
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