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- W2003244535 abstract "The pyruvic acid thiosemicarbazone was found to inhibitin vitro the soluble ornithine carbamoyl transferase as well as the enzyme in a mitochondria-rich cell fraction. For proving the inhibition of ornithine carbamoyl transferase in mitochondria-rich fraction a new method for DEAE-thin-layer chromatography of radiocarbon labelled citrulline and ornithine was used. The mitochondria prepared by discontinuous sucrose density gradient centrifugation are physiologically active and oxidized succinate under state 3 conditions. The respiratory control ratio was determined to 3.3. The results obtained show that this analogue of pyruvic acid is an inhibitor of ornithine carbamoyl transferase." @default.
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- W2003244535 date "1986-05-01" @default.
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- W2003244535 title "The effect of pyruvic acid thiosemicarbazone on ornithine carbamoyl transferase ofLycopersicon esculentum Mill" @default.
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- W2003244535 doi "https://doi.org/10.1007/bf02894593" @default.
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