FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003249734> ?p ?o ?g. }

• W2003249734 endingPage "369" @default.
• W2003249734 startingPage "361" @default.
• W2003249734 abstract "Abstract: Purpose : Many risk‐directed therapeutic protocols have been proposed in acute lymphoblastic leukemia (ALL). However, the relapse rates remain high. The effectiveness of each protocol depends on how quickly the clearance of blast cells is achieved. In an attempt to improve survival, by minimizing treatment toxicity and relapse rate, different therapeutic protocols were used every 3 yr in our Unit. Patients and Methods : During 1991–2000, 132 children with ALL were diagnosed in our Unit. Modified and intensified NY II and BFM protocols, in three consecutive periods [(Hematology/Oncology Pediatric Department of the University of Athens) HOPDA‐91, HOPDA‐94, HOPDA‐97] were used. Results : At a median follow‐up time of 96 months, the 8‐year overall survival (OS) was 88% ± 3%, whereas the event‐free survival (EFS) was 85% ± 3%. There was a significant increase of the 5‐year EFS of the high‐risk (HR) group through time (65% in HOPDA‐91 vs. 80% in HOPDA‐97), whereas EFS of the low risk (LR) group in HOPDA‐97 was 96%. Five cases relapsed (3.8%), four of which underwent successful bone marrow transplantation. Fifteen children died (13 diagnosed by 1996, two in the last 4 yr). Conclusion : Modification of the protocols significantly improved survival in both HR and LR groups. The intensified regimen in the LR group did not increase the adverse toxic events, but on the contrary was extremely effective." @default.
• W2003249734 created "2016-06-24" @default.
• W2003249734 creator A5009953499 @default.
• W2003249734 creator A5020858561 @default.
• W2003249734 creator A5029391119 @default.
• W2003249734 creator A5059953286 @default.
• W2003249734 creator A5069420342 @default.
• W2003249734 creator A5072379918 @default.
• W2003249734 creator A5088027451 @default.
• W2003249734 date "2005-09-28" @default.
• W2003249734 modified "2023-09-28" @default.
• W2003249734 title "Could intensified treatment in childhood acute lymphoblastic leukemia improve outcome independently of risk factors?" @default.
• W2003249734 cites W11202050 @default.
• W2003249734 cites W1801876107 @default.
• W2003249734 cites W1911319577 @default.
• W2003249734 cites W1939497674 @default.
• W2003249734 cites W1949104778 @default.
• W2003249734 cites W1966547883 @default.
• W2003249734 cites W1976897003 @default.
• W2003249734 cites W1982938019 @default.
• W2003249734 cites W1987588179 @default.
• W2003249734 cites W2007208181 @default.
• W2003249734 cites W2008735086 @default.
• W2003249734 cites W2015869717 @default.
• W2003249734 cites W2022371214 @default.
• W2003249734 cites W2028881763 @default.
• W2003249734 cites W2039677781 @default.
• W2003249734 cites W2048006890 @default.
• W2003249734 cites W2055406626 @default.
• W2003249734 cites W2057155310 @default.
• W2003249734 cites W2073813202 @default.
• W2003249734 cites W2083089310 @default.
• W2003249734 cites W2127153931 @default.
• W2003249734 cites W2127370636 @default.
• W2003249734 cites W2128546032 @default.
• W2003249734 cites W2138591172 @default.
• W2003249734 cites W2147996630 @default.
• W2003249734 cites W2154941073 @default.
• W2003249734 cites W2158706332 @default.
• W2003249734 cites W2165207521 @default.
• W2003249734 cites W2169291909 @default.
• W2003249734 cites W4376848446 @default.
• W2003249734 doi "https://doi.org/10.1111/j.1600-0609.2005.00527.x" @default.
• W2003249734 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16191084" @default.
• W2003249734 hasPublicationYear "2005" @default.
• W2003249734 type Work @default.
• W2003249734 sameAs 2003249734 @default.
• W2003249734 citedByCount "15" @default.
• W2003249734 countsByYear W20032497342013 @default.
• W2003249734 countsByYear W20032497342014 @default.
• W2003249734 countsByYear W20032497342015 @default.
• W2003249734 crossrefType "journal-article" @default.
• W2003249734 hasAuthorship W2003249734A5009953499 @default.
• W2003249734 hasAuthorship W2003249734A5020858561 @default.
• W2003249734 hasAuthorship W2003249734A5029391119 @default.
• W2003249734 hasAuthorship W2003249734A5059953286 @default.
• W2003249734 hasAuthorship W2003249734A5069420342 @default.
• W2003249734 hasAuthorship W2003249734A5072379918 @default.
• W2003249734 hasAuthorship W2003249734A5088027451 @default.
• W2003249734 hasConcept C126322002 @default.
• W2003249734 hasConcept C143998085 @default.
• W2003249734 hasConcept C187212893 @default.
• W2003249734 hasConcept C194409129 @default.
• W2003249734 hasConcept C197934379 @default.
• W2003249734 hasConcept C2778461978 @default.
• W2003249734 hasConcept C2781413609 @default.
• W2003249734 hasConcept C2909962599 @default.
• W2003249734 hasConcept C2911091166 @default.
• W2003249734 hasConcept C71924100 @default.
• W2003249734 hasConceptScore W2003249734C126322002 @default.
• W2003249734 hasConceptScore W2003249734C143998085 @default.
• W2003249734 hasConceptScore W2003249734C187212893 @default.
• W2003249734 hasConceptScore W2003249734C194409129 @default.
• W2003249734 hasConceptScore W2003249734C197934379 @default.
• W2003249734 hasConceptScore W2003249734C2778461978 @default.
• W2003249734 hasConceptScore W2003249734C2781413609 @default.
• W2003249734 hasConceptScore W2003249734C2909962599 @default.
• W2003249734 hasConceptScore W2003249734C2911091166 @default.
• W2003249734 hasConceptScore W2003249734C71924100 @default.
• W2003249734 hasIssue "5" @default.
• W2003249734 hasLocation W20032497341 @default.
• W2003249734 hasLocation W20032497342 @default.
• W2003249734 hasOpenAccess W2003249734 @default.
• W2003249734 hasPrimaryLocation W20032497341 @default.
• W2003249734 hasRelatedWork W2034542604 @default.
• W2003249734 hasRelatedWork W2065856818 @default.
• W2003249734 hasRelatedWork W2407161884 @default.
• W2003249734 hasRelatedWork W2410889947 @default.
• W2003249734 hasRelatedWork W2472355036 @default.
• W2003249734 hasRelatedWork W2584383839 @default.
• W2003249734 hasRelatedWork W3118107215 @default.
• W2003249734 hasRelatedWork W4231022123 @default.
• W2003249734 hasRelatedWork W4295836826 @default.
• W2003249734 hasRelatedWork W4322706357 @default.
• W2003249734 hasVolume "75" @default.
• W2003249734 isParatext "false" @default.
• W2003249734 isRetracted "false" @default.
• W2003249734 magId "2003249734" @default.

• next