FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003254651> ?p ?o ?g. }

• W2003254651 endingPage "882" @default.
• W2003254651 startingPage "867" @default.
• W2003254651 abstract "Primary cell culture was utilized to study the relationships between stress protein induction by zinc in vivo and cadmium toxicity in vitro. Effects of cadmium on cell viability were evaluated by the alamar blue assay, in conjunction with the ultrastructural morphology of cells by transmission electron microscopy. The expression of stress protein gene products was evaluated by 35S two-dimensional gel electrophoresis. The results showed cytotoxicity of CdCl2 at and above 129 μM (14.55 μg cadmium/mL medium) following 4 h of exposure. Prior zinc administration (20 mg zinc/kg, s.c, two daily doses) in vivo significantly protected the cells in vitro as demonstrated by improved cell viability. The 35S labeling of proteins induced by CdCl2 exposure clearly demonstrated for the first time that gene product of the 70-kDa family was induced in cultured rat proximal tubule cells which are the target cells for cadmium toxicity in vivo. Zinc in vivo pretreatment of animals induced proteins in the 90-, 70-, and 38-kDa families, which may act together with metallothionein to protect cells against cadmium toxicity. The results also indicate that the protective effect of zinc remains after the cells have been put in culture and thus provides a system in which we can study the changes that occur as a result of zinc exposure that decreases cadmium toxicity." @default.
• W2003254651 created "2016-06-24" @default.
• W2003254651 creator A5015044782 @default.
• W2003254651 creator A5028674241 @default.
• W2003254651 creator A5052440014 @default.
• W2003254651 creator A5060435800 @default.
• W2003254651 creator A5076332421 @default.
• W2003254651 creator A5090607148 @default.
• W2003254651 date "1996-01-01" @default.
• W2003254651 modified "2023-10-16" @default.
• W2003254651 title "Cytotoxicity, Zinc Protection, and Stress Protein Induction in Rat Proximal Tubule Cells Exposed to Cadmium Chloride in Primary Cell Culture" @default.
• W2003254651 cites W1549277283 @default.
• W2003254651 cites W1606423922 @default.
• W2003254651 cites W1614185919 @default.
• W2003254651 cites W1769448430 @default.
• W2003254651 cites W1970868538 @default.
• W2003254651 cites W1977716290 @default.
• W2003254651 cites W1983865296 @default.
• W2003254651 cites W1985502127 @default.
• W2003254651 cites W1985712270 @default.
• W2003254651 cites W1992800337 @default.
• W2003254651 cites W1994763875 @default.
• W2003254651 cites W2001373068 @default.
• W2003254651 cites W2012683394 @default.
• W2003254651 cites W2013242543 @default.
• W2003254651 cites W2014901209 @default.
• W2003254651 cites W2025562282 @default.
• W2003254651 cites W2028427144 @default.
• W2003254651 cites W2030475813 @default.
• W2003254651 cites W2037779780 @default.
• W2003254651 cites W2040914101 @default.
• W2003254651 cites W2054431943 @default.
• W2003254651 cites W2057830862 @default.
• W2003254651 cites W2060071007 @default.
• W2003254651 cites W2072891772 @default.
• W2003254651 cites W2074123457 @default.
• W2003254651 cites W2078914464 @default.
• W2003254651 cites W2079549399 @default.
• W2003254651 cites W2085925936 @default.
• W2003254651 cites W2086022817 @default.
• W2003254651 cites W2088923618 @default.
• W2003254651 cites W2090900055 @default.
• W2003254651 cites W2162288856 @default.
• W2003254651 cites W2165113979 @default.
• W2003254651 cites W2204252573 @default.
• W2003254651 cites W4293247451 @default.
• W2003254651 cites W4300834200 @default.
• W2003254651 doi "https://doi.org/10.3109/08860229609047713" @default.
• W2003254651 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8948521" @default.
• W2003254651 hasPublicationYear "1996" @default.
• W2003254651 type Work @default.
• W2003254651 sameAs 2003254651 @default.
• W2003254651 citedByCount "24" @default.
• W2003254651 countsByYear W20032546512012 @default.
• W2003254651 countsByYear W20032546512013 @default.
• W2003254651 countsByYear W20032546512014 @default.
• W2003254651 countsByYear W20032546512021 @default.
• W2003254651 crossrefType "journal-article" @default.
• W2003254651 hasAuthorship W2003254651A5015044782 @default.
• W2003254651 hasAuthorship W2003254651A5028674241 @default.
• W2003254651 hasAuthorship W2003254651A5052440014 @default.
• W2003254651 hasAuthorship W2003254651A5060435800 @default.
• W2003254651 hasAuthorship W2003254651A5076332421 @default.
• W2003254651 hasAuthorship W2003254651A5090607148 @default.
• W2003254651 hasConcept C109316439 @default.
• W2003254651 hasConcept C126322002 @default.
• W2003254651 hasConcept C150903083 @default.
• W2003254651 hasConcept C153911025 @default.
• W2003254651 hasConcept C178790620 @default.
• W2003254651 hasConcept C185592680 @default.
• W2003254651 hasConcept C202751555 @default.
• W2003254651 hasConcept C207001950 @default.
• W2003254651 hasConcept C20719415 @default.
• W2003254651 hasConcept C2778643788 @default.
• W2003254651 hasConcept C29730261 @default.
• W2003254651 hasConcept C53227056 @default.
• W2003254651 hasConcept C535196362 @default.
• W2003254651 hasConcept C54355233 @default.
• W2003254651 hasConcept C544657597 @default.
• W2003254651 hasConcept C55493867 @default.
• W2003254651 hasConcept C71924100 @default.
• W2003254651 hasConcept C81885089 @default.
• W2003254651 hasConcept C86803240 @default.
• W2003254651 hasConcept C95444343 @default.
• W2003254651 hasConceptScore W2003254651C109316439 @default.
• W2003254651 hasConceptScore W2003254651C126322002 @default.
• W2003254651 hasConceptScore W2003254651C150903083 @default.
• W2003254651 hasConceptScore W2003254651C153911025 @default.
• W2003254651 hasConceptScore W2003254651C178790620 @default.
• W2003254651 hasConceptScore W2003254651C185592680 @default.
• W2003254651 hasConceptScore W2003254651C202751555 @default.
• W2003254651 hasConceptScore W2003254651C207001950 @default.
• W2003254651 hasConceptScore W2003254651C20719415 @default.
• W2003254651 hasConceptScore W2003254651C2778643788 @default.
• W2003254651 hasConceptScore W2003254651C29730261 @default.
• W2003254651 hasConceptScore W2003254651C53227056 @default.
• W2003254651 hasConceptScore W2003254651C535196362 @default.
• W2003254651 hasConceptScore W2003254651C54355233 @default.

• next