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- W2003261172 abstract "Forty-eight patients scheduled to undergo spinal anaesthesia were allocated to three groups of 16 each according to ASA classification I-II-III. Each patient received a fluid load of 7 ml kg-1 and either ephedrine 12.5 mg i.v. and 37.5 mg i.m., or placebo. Twelve patients in the placebo groups developed a maximal decrease in mean arterial pressure exceeding 20%. Five of these (one in ASA II and four in ASA III) developed a decrease exceeding 33% and required treatment. In ASA risk group III, all patients in the placebo group had a decrease in mean arterial pressure exceeding 20%; in 50% of these patients, the decrease exceeded 33%. We conclude that prophylactic ephedrine is desirable for spinal anaesthesia, especially in ASA III patients." @default.
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- W2003261172 date "1989-09-01" @default.
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- W2003261172 title "PROPHYLACTIC EPHEDRINE DURING SPINAL ANAESTHESIA: DOUBLE-BLIND STUDY IN PATIENTS IN ASA GROUPS I–III" @default.
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- W2003261172 doi "https://doi.org/10.1093/bja/63.3.340" @default.
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