Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003267245> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W2003267245 abstract "The HMGA architectural nuclear factors are involved in chromatin dynamics and their overexpression has been strongly linked to the neoplastic transformation process. Here we investigate the expression and post-translational modifications (PTMs) of HMGA proteins (HMGA1a, HMGA1b and HMGA2) in the rat prostatic cancer Dunning model (G, AT-1, and MAT-Ly-Lu cell lines). We demonstrate the expression of HMGA2, in addition to HMGA1a and HMGA1b, in both the anaplastic cell lines AT-1 and MAT-Ly-Lu and an extremely specific HMGA1a mono-methylation only in the most metastatic cell line MAT-Ly-Lu. The HMGA ectopic expression in HMGA-negative Dunning G cells does not significantly alter their growth ability, suggesting that, although HMGA expression is necessary for the progression of neoplastic transformation in several cellular models, in these cells it is not sufficient. These data suggest exploring HMGA2 as a potential marker in human prostate tumor and moreover indicate PTMs as an additional tool in the staging of tumor progression." @default.
- W2003267245 created "2016-06-24" @default.
- W2003267245 creator A5002287446 @default.
- W2003267245 creator A5007157411 @default.
- W2003267245 creator A5013122680 @default.
- W2003267245 creator A5052385516 @default.
- W2003267245 creator A5071139479 @default.
- W2003267245 creator A5091124826 @default.
- W2003267245 creator A5091590601 @default.
- W2003267245 creator A5091627936 @default.
- W2003267245 date "2005-02-01" @default.
- W2003267245 modified "2023-09-25" @default.
- W2003267245 title "Differential HMGA expression and post-translational modifications in prostatic tumor cells" @default.
- W2003267245 doi "https://doi.org/10.3892/ijo.26.2.515" @default.
- W2003267245 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15645138" @default.
- W2003267245 hasPublicationYear "2005" @default.
- W2003267245 type Work @default.
- W2003267245 sameAs 2003267245 @default.
- W2003267245 citedByCount "5" @default.
- W2003267245 countsByYear W20032672452012 @default.
- W2003267245 countsByYear W20032672452013 @default.
- W2003267245 crossrefType "journal-article" @default.
- W2003267245 hasAuthorship W2003267245A5002287446 @default.
- W2003267245 hasAuthorship W2003267245A5007157411 @default.
- W2003267245 hasAuthorship W2003267245A5013122680 @default.
- W2003267245 hasAuthorship W2003267245A5052385516 @default.
- W2003267245 hasAuthorship W2003267245A5071139479 @default.
- W2003267245 hasAuthorship W2003267245A5091124826 @default.
- W2003267245 hasAuthorship W2003267245A5091590601 @default.
- W2003267245 hasAuthorship W2003267245A5091627936 @default.
- W2003267245 hasConcept C104317684 @default.
- W2003267245 hasConcept C121608353 @default.
- W2003267245 hasConcept C145059251 @default.
- W2003267245 hasConcept C1491633281 @default.
- W2003267245 hasConcept C153911025 @default.
- W2003267245 hasConcept C2529059 @default.
- W2003267245 hasConcept C2781018059 @default.
- W2003267245 hasConcept C29537977 @default.
- W2003267245 hasConcept C2993273003 @default.
- W2003267245 hasConcept C31033888 @default.
- W2003267245 hasConcept C502942594 @default.
- W2003267245 hasConcept C54355233 @default.
- W2003267245 hasConcept C555283112 @default.
- W2003267245 hasConcept C81885089 @default.
- W2003267245 hasConcept C86803240 @default.
- W2003267245 hasConcept C95444343 @default.
- W2003267245 hasConcept C97037327 @default.
- W2003267245 hasConceptScore W2003267245C104317684 @default.
- W2003267245 hasConceptScore W2003267245C121608353 @default.
- W2003267245 hasConceptScore W2003267245C145059251 @default.
- W2003267245 hasConceptScore W2003267245C1491633281 @default.
- W2003267245 hasConceptScore W2003267245C153911025 @default.
- W2003267245 hasConceptScore W2003267245C2529059 @default.
- W2003267245 hasConceptScore W2003267245C2781018059 @default.
- W2003267245 hasConceptScore W2003267245C29537977 @default.
- W2003267245 hasConceptScore W2003267245C2993273003 @default.
- W2003267245 hasConceptScore W2003267245C31033888 @default.
- W2003267245 hasConceptScore W2003267245C502942594 @default.
- W2003267245 hasConceptScore W2003267245C54355233 @default.
- W2003267245 hasConceptScore W2003267245C555283112 @default.
- W2003267245 hasConceptScore W2003267245C81885089 @default.
- W2003267245 hasConceptScore W2003267245C86803240 @default.
- W2003267245 hasConceptScore W2003267245C95444343 @default.
- W2003267245 hasConceptScore W2003267245C97037327 @default.
- W2003267245 hasLocation W20032672451 @default.
- W2003267245 hasLocation W20032672452 @default.
- W2003267245 hasOpenAccess W2003267245 @default.
- W2003267245 hasPrimaryLocation W20032672451 @default.
- W2003267245 hasRelatedWork W1104561468 @default.
- W2003267245 hasRelatedWork W1976172407 @default.
- W2003267245 hasRelatedWork W2026029310 @default.
- W2003267245 hasRelatedWork W2109383678 @default.
- W2003267245 hasRelatedWork W2124598671 @default.
- W2003267245 hasRelatedWork W2407280763 @default.
- W2003267245 hasRelatedWork W2535807463 @default.
- W2003267245 hasRelatedWork W2601368393 @default.
- W2003267245 hasRelatedWork W2791925378 @default.
- W2003267245 hasRelatedWork W3212083035 @default.
- W2003267245 isParatext "false" @default.
- W2003267245 isRetracted "false" @default.
- W2003267245 magId "2003267245" @default.
- W2003267245 workType "article" @default.