Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003285867> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2003285867 endingPage "184" @default.
- W2003285867 startingPage "177" @default.
- W2003285867 abstract "Propionic acidemia occasionally produces a toxic encephalopathy resembling Reye's syndrome, indicating disruption of mitochondrial metabolism. Liver mitochondria respiratory control ratios were reduced 46% by 5 mM propionate; inhibition correlated with matrix propionyl-CoA levels. L-Malate prevented the toxic effect of propionate and reduced the propionyl-CoA matrix concentration by 62%. The beneficial effect of L-malate is apparently due to stimulation of succinate efflux because the effect is blocked by benzylmalonate, an inhibitor of the dicarboxylate carrier. Matrix concentration of label from [1-14C]propionate was not affected by L-malate and/or benzylmalonate. L-Malate may be useful in the treatment of patients with propionic acidemia." @default.
- W2003285867 created "2016-06-24" @default.
- W2003285867 creator A5011403518 @default.
- W2003285867 creator A5025284161 @default.
- W2003285867 creator A5050312801 @default.
- W2003285867 date "1991-10-01" @default.
- W2003285867 modified "2023-09-27" @default.
- W2003285867 title "The effect of malate on propionate mitochondrial toxicity" @default.
- W2003285867 cites W1550542945 @default.
- W2003285867 cites W1775749144 @default.
- W2003285867 cites W1963599172 @default.
- W2003285867 cites W1969814448 @default.
- W2003285867 cites W1970751523 @default.
- W2003285867 cites W1972021086 @default.
- W2003285867 cites W1973799750 @default.
- W2003285867 cites W1986990864 @default.
- W2003285867 cites W1992285776 @default.
- W2003285867 cites W2003274002 @default.
- W2003285867 cites W2005838942 @default.
- W2003285867 cites W2008341411 @default.
- W2003285867 cites W2008946840 @default.
- W2003285867 cites W2010696845 @default.
- W2003285867 cites W2015519267 @default.
- W2003285867 cites W2033732709 @default.
- W2003285867 cites W2053625997 @default.
- W2003285867 cites W2068832345 @default.
- W2003285867 cites W2070660966 @default.
- W2003285867 cites W2228372945 @default.
- W2003285867 cites W2921018620 @default.
- W2003285867 cites W40640842 @default.
- W2003285867 doi "https://doi.org/10.1016/0885-4505(91)90065-s" @default.
- W2003285867 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1782009" @default.
- W2003285867 hasPublicationYear "1991" @default.
- W2003285867 type Work @default.
- W2003285867 sameAs 2003285867 @default.
- W2003285867 citedByCount "8" @default.
- W2003285867 countsByYear W20032858672013 @default.
- W2003285867 countsByYear W20032858672016 @default.
- W2003285867 crossrefType "journal-article" @default.
- W2003285867 hasAuthorship W2003285867A5011403518 @default.
- W2003285867 hasAuthorship W2003285867A5025284161 @default.
- W2003285867 hasAuthorship W2003285867A5050312801 @default.
- W2003285867 hasConcept C11701378 @default.
- W2003285867 hasConcept C126322002 @default.
- W2003285867 hasConcept C132901563 @default.
- W2003285867 hasConcept C134018914 @default.
- W2003285867 hasConcept C181199279 @default.
- W2003285867 hasConcept C185592680 @default.
- W2003285867 hasConcept C200082930 @default.
- W2003285867 hasConcept C24998067 @default.
- W2003285867 hasConcept C2780014933 @default.
- W2003285867 hasConcept C28859421 @default.
- W2003285867 hasConcept C29730261 @default.
- W2003285867 hasConcept C55493867 @default.
- W2003285867 hasConcept C62231903 @default.
- W2003285867 hasConcept C71924100 @default.
- W2003285867 hasConcept C86803240 @default.
- W2003285867 hasConcept C98274493 @default.
- W2003285867 hasConcept C98539663 @default.
- W2003285867 hasConceptScore W2003285867C11701378 @default.
- W2003285867 hasConceptScore W2003285867C126322002 @default.
- W2003285867 hasConceptScore W2003285867C132901563 @default.
- W2003285867 hasConceptScore W2003285867C134018914 @default.
- W2003285867 hasConceptScore W2003285867C181199279 @default.
- W2003285867 hasConceptScore W2003285867C185592680 @default.
- W2003285867 hasConceptScore W2003285867C200082930 @default.
- W2003285867 hasConceptScore W2003285867C24998067 @default.
- W2003285867 hasConceptScore W2003285867C2780014933 @default.
- W2003285867 hasConceptScore W2003285867C28859421 @default.
- W2003285867 hasConceptScore W2003285867C29730261 @default.
- W2003285867 hasConceptScore W2003285867C55493867 @default.
- W2003285867 hasConceptScore W2003285867C62231903 @default.
- W2003285867 hasConceptScore W2003285867C71924100 @default.
- W2003285867 hasConceptScore W2003285867C86803240 @default.
- W2003285867 hasConceptScore W2003285867C98274493 @default.
- W2003285867 hasConceptScore W2003285867C98539663 @default.
- W2003285867 hasIssue "2" @default.
- W2003285867 hasLocation W20032858671 @default.
- W2003285867 hasLocation W20032858672 @default.
- W2003285867 hasOpenAccess W2003285867 @default.
- W2003285867 hasPrimaryLocation W20032858671 @default.
- W2003285867 hasRelatedWork W1984619393 @default.
- W2003285867 hasRelatedWork W2034768996 @default.
- W2003285867 hasRelatedWork W2041949500 @default.
- W2003285867 hasRelatedWork W2042786471 @default.
- W2003285867 hasRelatedWork W2054992011 @default.
- W2003285867 hasRelatedWork W2060618991 @default.
- W2003285867 hasRelatedWork W2064416809 @default.
- W2003285867 hasRelatedWork W2092630182 @default.
- W2003285867 hasRelatedWork W2163700154 @default.
- W2003285867 hasRelatedWork W2419480917 @default.
- W2003285867 hasVolume "46" @default.
- W2003285867 isParatext "false" @default.
- W2003285867 isRetracted "false" @default.
- W2003285867 magId "2003285867" @default.
- W2003285867 workType "article" @default.