Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003291630> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2003291630 endingPage "114" @default.
- W2003291630 startingPage "99" @default.
- W2003291630 abstract "1. In fifteen experiments, single microvessels in the exposed mesenteries of pithed frogs were perfused with Ringer solutions containing bovine serum albumin (40 mg ml-1). For each vessel, the hydraulic permeability of its walls (Lp) and effective osmotic pressure exerted across them (sigma delta pi) were determined from measurements of fluid filtration rates at two capillary pressures (Michel, Mason, Curry, Tooke & Hunter, 1974) before and at predetermined times after the tissue temperature had been raised abruptly from approximately 15 degrees C to 30-35 degrees C. Temperatures greater than 30 degrees C appear to damage the tissues of frogs acclimatized to temperatures of 5-10 degrees C. 2. In fourteen out of fifteen experiments Lp rose when the temperature was raised to 30-35 degrees C. In twelve of these experiments the increase in Lp was greater than expected from the fall in water viscosity with temperature, and was progressive. In five vessels where measurements were made 1-2 min after tissue temperature was raised, Lp increased from an initial mean value (+/- S.E.M.) of 3.76 (+/- 0.54) x 10(-3) micron s-1 cmH2O-1 to one of 8.72 (+/- 1.68) x 10(-3) micron s-1 cmH2O-1. In nine vessels where measurements were made at 10 min after tissue temperature was raised, Lp increased from an initial mean value of 4.03 (+/- 0.72) x 10(-3) micron s-1 cmH2O-1 to one of 16.9 (+/- 3.5) x 10(-3) micron s-1 cmH2O-1. Further increases in Lp were seen at 15 and 20 min. 3. The changes in the effective osmotic pressure opposing filtration, sigma delta pi, were very variable. Out of the twelve vessels which showed large changes in Lp with tissue heating, four showed no reduction in sigma delta pi after 10 min, though sigma delta pi fell in three of these vessels at 15 min. In the other eight vessels, sigma delta pi fell as Lp rose. A quantitative theory developed in this paper allowed the changes in sigma delta pi to be analysed in terms of a component across the regions of vessel wall of increased permeability (sigma H delta pi H) and a component across regions where Lp was unchanged. In six vessels sigma H delta pi H approximated to zero; in two vessels sigma H delta pi H was 6.2 and 4.5 cmH2O.(ABSTRACT TRUNCATED AT 400 WORDS)" @default.
- W2003291630 created "2016-06-24" @default.
- W2003291630 creator A5004825763 @default.
- W2003291630 creator A5015829085 @default.
- W2003291630 creator A5089100867 @default.
- W2003291630 date "1988-01-01" @default.
- W2003291630 modified "2023-09-23" @default.
- W2003291630 title "Inflammatory changes in permeability and ultrastructure of single vessels in the frog mesenteric microcirculation." @default.
- W2003291630 cites W1625366430 @default.
- W2003291630 cites W1965018133 @default.
- W2003291630 cites W1966196236 @default.
- W2003291630 cites W1975239830 @default.
- W2003291630 cites W1989678248 @default.
- W2003291630 cites W1997271305 @default.
- W2003291630 cites W2004554331 @default.
- W2003291630 cites W2011766447 @default.
- W2003291630 cites W2016571976 @default.
- W2003291630 cites W2036721009 @default.
- W2003291630 cites W2091166697 @default.
- W2003291630 cites W2137845396 @default.
- W2003291630 cites W2137847399 @default.
- W2003291630 cites W2170200362 @default.
- W2003291630 cites W2395585766 @default.
- W2003291630 cites W2410850149 @default.
- W2003291630 cites W2581605534 @default.
- W2003291630 doi "https://doi.org/10.1113/jphysiol.1988.sp016910" @default.
- W2003291630 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1191985" @default.
- W2003291630 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3261792" @default.
- W2003291630 hasPublicationYear "1988" @default.
- W2003291630 type Work @default.
- W2003291630 sameAs 2003291630 @default.
- W2003291630 citedByCount "52" @default.
- W2003291630 countsByYear W20032916302012 @default.
- W2003291630 countsByYear W20032916302013 @default.
- W2003291630 countsByYear W20032916302014 @default.
- W2003291630 countsByYear W20032916302017 @default.
- W2003291630 countsByYear W20032916302018 @default.
- W2003291630 countsByYear W20032916302022 @default.
- W2003291630 crossrefType "journal-article" @default.
- W2003291630 hasAuthorship W2003291630A5004825763 @default.
- W2003291630 hasAuthorship W2003291630A5015829085 @default.
- W2003291630 hasAuthorship W2003291630A5089100867 @default.
- W2003291630 hasBestOaLocation W20032916302 @default.
- W2003291630 hasConcept C105702510 @default.
- W2003291630 hasConcept C113045295 @default.
- W2003291630 hasConcept C113196181 @default.
- W2003291630 hasConcept C120882062 @default.
- W2003291630 hasConcept C126322002 @default.
- W2003291630 hasConcept C12722491 @default.
- W2003291630 hasConcept C134018914 @default.
- W2003291630 hasConcept C147789679 @default.
- W2003291630 hasConcept C185592680 @default.
- W2003291630 hasConcept C192562407 @default.
- W2003291630 hasConcept C2778872873 @default.
- W2003291630 hasConcept C2910118531 @default.
- W2003291630 hasConcept C41625074 @default.
- W2003291630 hasConcept C43617362 @default.
- W2003291630 hasConcept C55493867 @default.
- W2003291630 hasConcept C71924100 @default.
- W2003291630 hasConcept C86803240 @default.
- W2003291630 hasConceptScore W2003291630C105702510 @default.
- W2003291630 hasConceptScore W2003291630C113045295 @default.
- W2003291630 hasConceptScore W2003291630C113196181 @default.
- W2003291630 hasConceptScore W2003291630C120882062 @default.
- W2003291630 hasConceptScore W2003291630C126322002 @default.
- W2003291630 hasConceptScore W2003291630C12722491 @default.
- W2003291630 hasConceptScore W2003291630C134018914 @default.
- W2003291630 hasConceptScore W2003291630C147789679 @default.
- W2003291630 hasConceptScore W2003291630C185592680 @default.
- W2003291630 hasConceptScore W2003291630C192562407 @default.
- W2003291630 hasConceptScore W2003291630C2778872873 @default.
- W2003291630 hasConceptScore W2003291630C2910118531 @default.
- W2003291630 hasConceptScore W2003291630C41625074 @default.
- W2003291630 hasConceptScore W2003291630C43617362 @default.
- W2003291630 hasConceptScore W2003291630C55493867 @default.
- W2003291630 hasConceptScore W2003291630C71924100 @default.
- W2003291630 hasConceptScore W2003291630C86803240 @default.
- W2003291630 hasIssue "1" @default.
- W2003291630 hasLocation W20032916301 @default.
- W2003291630 hasLocation W20032916302 @default.
- W2003291630 hasLocation W20032916303 @default.
- W2003291630 hasOpenAccess W2003291630 @default.
- W2003291630 hasPrimaryLocation W20032916301 @default.
- W2003291630 hasRelatedWork W1796520925 @default.
- W2003291630 hasRelatedWork W1969838599 @default.
- W2003291630 hasRelatedWork W2006555460 @default.
- W2003291630 hasRelatedWork W2022395297 @default.
- W2003291630 hasRelatedWork W2088159286 @default.
- W2003291630 hasRelatedWork W2318142750 @default.
- W2003291630 hasRelatedWork W2503979065 @default.
- W2003291630 hasRelatedWork W2899084033 @default.
- W2003291630 hasRelatedWork W3021189511 @default.
- W2003291630 hasRelatedWork W3101690170 @default.
- W2003291630 hasVolume "395" @default.
- W2003291630 isParatext "false" @default.
- W2003291630 isRetracted "false" @default.
- W2003291630 magId "2003291630" @default.
- W2003291630 workType "article" @default.