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- W2003327011 abstract "Consciousness mood, identity and personality are all emergent properties from whole-brain organizations; these are typically disturbed in psychiatric disorders. This work proposes that the underlying etiopathology of mental disorders originates from disturbances to global brain dynamics, or Globalopathies that are divided into three major interdependent types (1) Resting-State Networkpathies, in personality disorders, (2) Entropiathies in mood disorders, and (3) Connectopathies in psychosis and schizophrenia spectrum disorders. Novel approaches of processing signals from the brain are beginning to reveal brain organization in health and disease. For example a small world network has been described for optimal brain functions and breakdown of that organization might underlie relevant psychiatric manifestations. A novel diagnostic reformulation can be generated based on pathologies of whole brain organizations, such new brain related diagnostic nosology is testable and thus can be validated. Once validated Globalopathies can provide for Global-therapies i.e., interventions that can reorganize the brain and cure psychiatric disorders. The technology for such interventions is becoming available." @default.
- W2003327011 created "2016-06-24" @default.
- W2003327011 creator A5081057585 @default.
- W2003327011 date "2013-12-01" @default.
- W2003327011 modified "2023-10-01" @default.
- W2003327011 title "Brain “Globalopathies” cause mental disorders" @default.
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- W2003327011 doi "https://doi.org/10.1016/j.mehy.2013.09.032" @default.
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