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- W2003368093 abstract "Background: This study has two goals: 1) to establish a generalizable model of the symptoms observed in outpatients with major depressive disorder (MDD); and 2) to compare symptom coverage of the Inventory of Depressive Symptomatology, Clinician-Rated (IDS-C) and Self-Report (IDS-SR) to that of the Hamilton Depression Rating Scale (HDRS) and Beck Depression Inventory (BDI).Methods: A factor analysis of IDS-C, IDS-SR, HDRS, and BDI items was carried out on 324 adult outpatients with MDD. Patients with coexisting Axis I or III illness or those taking psychotropic medication were excluded.Results: Ten primary factors were identified, six of which were substantially intercorrelated, defining a second-order factor of general depression severity. Schmid–Leiman orthogonalization identified the symptoms most associated with general severity.Conclusions: The IDS provided more complete factor coverage than did the HDRS or BDI and thus may be more useful in research on symptom profiles." @default.
- W2003368093 created "2016-06-24" @default.
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- W2003368093 date "2008-08-01" @default.
- W2003368093 modified "2023-09-25" @default.
- W2003368093 title "C.07.03 Latest developments in the management of major depressive disorder" @default.
- W2003368093 doi "https://doi.org/10.1016/s0924-977x(08)70920-9" @default.
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