Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003408315> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W2003408315 endingPage "70" @default.
- W2003408315 startingPage "64" @default.
- W2003408315 abstract "125I-nerve growth factor (NGF) was found to be internalized and translocated to the nucleus of SKBr5 breast carcinoma cells. The cytoplasm and chromatin isolated from nonmitotic cells accumulated two- and five-fold, respectively, more of 125I-NGF than the cells undergoing mitosis. MAb 20.4 developed against the NGF cell surface receptor immunoprecipitated the 80,000 M(r) receptor from plasma membrane and two protein species from the chromatin; 90,000 M(r) (major band) and 200,000 M(r) (minor band). In SKBr5 cells, binding of NGF to the chromatin did not affect synthesis of rRNA. Proliferation of SKBr5 cells was slightly stimulated by NGF. In control melanoma A875 cells, which express the 230,000 M(r) chromatin receptor, NGF inhibited both rRNA synthesis and cell proliferation. We suggest that the 90,000 M(r) chromatin receptor expressed by SKBr5 cells represents a nonactive, ligand-binding subunit of the high molecular weight receptor for NGF. The critical role of the chromatin receptor for NGF in rRNA-dependent cell proliferation is discussed." @default.
- W2003408315 created "2016-06-24" @default.
- W2003408315 creator A5072952313 @default.
- W2003408315 date "1993-01-01" @default.
- W2003408315 modified "2023-09-26" @default.
- W2003408315 title "Identification of the cell surface and nuclear receptors for NGF in a breast carcinoma cell line" @default.
- W2003408315 cites W1270455421 @default.
- W2003408315 cites W1521573047 @default.
- W2003408315 cites W186804289 @default.
- W2003408315 cites W1967454225 @default.
- W2003408315 cites W1970903579 @default.
- W2003408315 cites W1985822867 @default.
- W2003408315 cites W1987395633 @default.
- W2003408315 cites W1998103617 @default.
- W2003408315 cites W2002472058 @default.
- W2003408315 cites W2018847325 @default.
- W2003408315 cites W2020333978 @default.
- W2003408315 cites W2021939146 @default.
- W2003408315 cites W2040421525 @default.
- W2003408315 cites W2069748621 @default.
- W2003408315 cites W2073611916 @default.
- W2003408315 cites W2076203359 @default.
- W2003408315 cites W2091309613 @default.
- W2003408315 cites W2100837269 @default.
- W2003408315 cites W2109661363 @default.
- W2003408315 cites W2154105002 @default.
- W2003408315 cites W2164658118 @default.
- W2003408315 doi "https://doi.org/10.1002/jcp.1041540109" @default.
- W2003408315 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7678267" @default.
- W2003408315 hasPublicationYear "1993" @default.
- W2003408315 type Work @default.
- W2003408315 sameAs 2003408315 @default.
- W2003408315 citedByCount "7" @default.
- W2003408315 crossrefType "journal-article" @default.
- W2003408315 hasAuthorship W2003408315A5072952313 @default.
- W2003408315 hasConcept C1491633281 @default.
- W2003408315 hasConcept C153911025 @default.
- W2003408315 hasConcept C170493617 @default.
- W2003408315 hasConcept C190062978 @default.
- W2003408315 hasConcept C197462201 @default.
- W2003408315 hasConcept C2778423431 @default.
- W2003408315 hasConcept C54355233 @default.
- W2003408315 hasConcept C552990157 @default.
- W2003408315 hasConcept C55493867 @default.
- W2003408315 hasConcept C62112901 @default.
- W2003408315 hasConcept C81885089 @default.
- W2003408315 hasConcept C83640560 @default.
- W2003408315 hasConcept C86803240 @default.
- W2003408315 hasConcept C93304396 @default.
- W2003408315 hasConcept C95444343 @default.
- W2003408315 hasConceptScore W2003408315C1491633281 @default.
- W2003408315 hasConceptScore W2003408315C153911025 @default.
- W2003408315 hasConceptScore W2003408315C170493617 @default.
- W2003408315 hasConceptScore W2003408315C190062978 @default.
- W2003408315 hasConceptScore W2003408315C197462201 @default.
- W2003408315 hasConceptScore W2003408315C2778423431 @default.
- W2003408315 hasConceptScore W2003408315C54355233 @default.
- W2003408315 hasConceptScore W2003408315C552990157 @default.
- W2003408315 hasConceptScore W2003408315C55493867 @default.
- W2003408315 hasConceptScore W2003408315C62112901 @default.
- W2003408315 hasConceptScore W2003408315C81885089 @default.
- W2003408315 hasConceptScore W2003408315C83640560 @default.
- W2003408315 hasConceptScore W2003408315C86803240 @default.
- W2003408315 hasConceptScore W2003408315C93304396 @default.
- W2003408315 hasConceptScore W2003408315C95444343 @default.
- W2003408315 hasIssue "1" @default.
- W2003408315 hasLocation W20034083151 @default.
- W2003408315 hasLocation W20034083152 @default.
- W2003408315 hasOpenAccess W2003408315 @default.
- W2003408315 hasPrimaryLocation W20034083151 @default.
- W2003408315 hasRelatedWork W1557687412 @default.
- W2003408315 hasRelatedWork W1985526447 @default.
- W2003408315 hasRelatedWork W1993524104 @default.
- W2003408315 hasRelatedWork W2067501728 @default.
- W2003408315 hasRelatedWork W2082235956 @default.
- W2003408315 hasRelatedWork W2084640688 @default.
- W2003408315 hasRelatedWork W2278670241 @default.
- W2003408315 hasRelatedWork W2363880822 @default.
- W2003408315 hasRelatedWork W2473201704 @default.
- W2003408315 hasRelatedWork W4232284067 @default.
- W2003408315 hasVolume "154" @default.
- W2003408315 isParatext "false" @default.
- W2003408315 isRetracted "false" @default.
- W2003408315 magId "2003408315" @default.
- W2003408315 workType "article" @default.