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• W2003418092 abstract "Precise editing of human genomes in pluripotent stem cells by homology-driven repair of targeted nuclease-induced cleavage has been hindered by the difficulty of isolating rare clones. We developed an efficient method to capture rare mutational events, enabling isolation of mutant lines with single-base substitutions without antibiotic selection. This method facilitates efficient induction or reversion of mutations associated with human disease in isogenic human induced pluripotent stem cells." @default.
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• W2003418092 date "2014-02-09" @default.
• W2003418092 modified "2023-10-10" @default.
• W2003418092 title "Isolation of single-base genome-edited human iPS cells without antibiotic selection" @default.
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• W2003418092 doi "https://doi.org/10.1038/nmeth.2840" @default.
• W2003418092 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4063274" @default.
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