Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003443527> ?p ?o ?g. }
- W2003443527 endingPage "227" @default.
- W2003443527 startingPage "208" @default.
- W2003443527 abstract "Many Americans use complementary and alternative medicine (CAM) to prevent or alleviate common illnesses, and these medicines are commonly used by individuals with cancer.These medicines or botanicals share the same metabolic and transport proteins, including cytochrome P450 enzymes (CYP), glucuronosyltransferases (UGTs), and P-glycoprotein (Pgp), with over-the-counter and prescription medicines increasing the likelihood of drug—botanical interactions.This review provides a brief description of the different proteins, such as CYPs, UGTs, and Pgp.The potential effects of drug—botanical interactions on the pharmacokinetics and pharmacodynamics of the drug or botanical and a summary of the more common models used to study drug metabolism are described.The remaining portion of this review summarizes the data extracted from several laboratory, animal, and clinical studies that describe the metabolism, transport, and potential interactions of 8 selected botanicals. The 8 botanicals include black cohosh, Echinacea, garlic, Gingko biloba, green tea, kava, milk thistle, and St John’s wort; these botanicals are among some of the more common botanicals taken by individuals with cancer.These examples are included to demonstrate how to interpret the different studies and how to use these data to predict the likelihood of a clinically significant drug—botanical interaction." @default.
- W2003443527 created "2016-06-24" @default.
- W2003443527 creator A5065397717 @default.
- W2003443527 creator A5075260289 @default.
- W2003443527 creator A5091341478 @default.
- W2003443527 date "2009-08-11" @default.
- W2003443527 modified "2023-10-09" @default.
- W2003443527 title "Drug—Botanical Interactions: A Review of the Laboratory, Animal, and Human Data for 8 Common Botanicals" @default.
- W2003443527 cites W100877704 @default.
- W2003443527 cites W1481796632 @default.
- W2003443527 cites W1505525797 @default.
- W2003443527 cites W1548404106 @default.
- W2003443527 cites W1650615725 @default.
- W2003443527 cites W1785872465 @default.
- W2003443527 cites W1938174098 @default.
- W2003443527 cites W1965610744 @default.
- W2003443527 cites W1966006812 @default.
- W2003443527 cites W1967782384 @default.
- W2003443527 cites W1968593374 @default.
- W2003443527 cites W1968661696 @default.
- W2003443527 cites W1969477792 @default.
- W2003443527 cites W1971041530 @default.
- W2003443527 cites W1973784661 @default.
- W2003443527 cites W1977526476 @default.
- W2003443527 cites W1978472590 @default.
- W2003443527 cites W1980552125 @default.
- W2003443527 cites W1982593480 @default.
- W2003443527 cites W1984173811 @default.
- W2003443527 cites W1984277226 @default.
- W2003443527 cites W1984802375 @default.
- W2003443527 cites W1985410301 @default.
- W2003443527 cites W1986357882 @default.
- W2003443527 cites W1986683769 @default.
- W2003443527 cites W1987802481 @default.
- W2003443527 cites W1989242891 @default.
- W2003443527 cites W1990164354 @default.
- W2003443527 cites W1992250421 @default.
- W2003443527 cites W1992334728 @default.
- W2003443527 cites W1992907029 @default.
- W2003443527 cites W1994585405 @default.
- W2003443527 cites W1995167508 @default.
- W2003443527 cites W1995407409 @default.
- W2003443527 cites W1997271604 @default.
- W2003443527 cites W1997577356 @default.
- W2003443527 cites W1997678718 @default.
- W2003443527 cites W1999014683 @default.
- W2003443527 cites W1999041958 @default.
- W2003443527 cites W1999390288 @default.
- W2003443527 cites W2000261986 @default.
- W2003443527 cites W2004281677 @default.
- W2003443527 cites W2004670440 @default.
- W2003443527 cites W2006233586 @default.
- W2003443527 cites W2006268588 @default.
- W2003443527 cites W2006532982 @default.
- W2003443527 cites W2007848784 @default.
- W2003443527 cites W2009002701 @default.
- W2003443527 cites W2009864991 @default.
- W2003443527 cites W2009952114 @default.
- W2003443527 cites W2012396546 @default.
- W2003443527 cites W2013020516 @default.
- W2003443527 cites W2013356649 @default.
- W2003443527 cites W2016219959 @default.
- W2003443527 cites W2017189393 @default.
- W2003443527 cites W2018904930 @default.
- W2003443527 cites W2019388528 @default.
- W2003443527 cites W2020245539 @default.
- W2003443527 cites W2020265334 @default.
- W2003443527 cites W2020914491 @default.
- W2003443527 cites W2021275946 @default.
- W2003443527 cites W2021781593 @default.
- W2003443527 cites W2021993096 @default.
- W2003443527 cites W2022541836 @default.
- W2003443527 cites W2025576842 @default.
- W2003443527 cites W2025663121 @default.
- W2003443527 cites W2026107285 @default.
- W2003443527 cites W2026330543 @default.
- W2003443527 cites W2027077891 @default.
- W2003443527 cites W2027306908 @default.
- W2003443527 cites W2027561440 @default.
- W2003443527 cites W2028091438 @default.
- W2003443527 cites W2028536981 @default.
- W2003443527 cites W2028623197 @default.
- W2003443527 cites W2029310284 @default.
- W2003443527 cites W2030873577 @default.
- W2003443527 cites W2031345014 @default.
- W2003443527 cites W2031661886 @default.
- W2003443527 cites W2032531780 @default.
- W2003443527 cites W2033686460 @default.
- W2003443527 cites W2034400329 @default.
- W2003443527 cites W2035662347 @default.
- W2003443527 cites W2035989002 @default.
- W2003443527 cites W2038014794 @default.
- W2003443527 cites W2038811203 @default.
- W2003443527 cites W2039309193 @default.
- W2003443527 cites W2039495159 @default.
- W2003443527 cites W2040106948 @default.
- W2003443527 cites W2041801408 @default.
- W2003443527 cites W2041813321 @default.