FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003451199> ?p ?o ?g. }

• W2003451199 endingPage "347" @default.
• W2003451199 startingPage "338" @default.
• W2003451199 abstract "An optimized phosphorous ((31)P) three-dimensional chemical-shift imaging (3D-CSI) protocol was developed at 4 T to study the phospholipid metabolism from discrete regions in the human brain without the need for (1)H-decoupling or nuclear Overhauser enhancement (NOE). In this study, a spherically bound, weighted average, random point omission 3D-CSI technique was developed and tested, based on methods proposed in the literature. The technique yields a significant (p < 0.001, two-tailed, 5% confidence level) increase in signal-to-noise (SNR) efficiency over conventional 3D-CSI (phantom 32%), without an increase in voxel bleedthrough. An automated time-domain fitting procedure utilizing prior spectral knowledge quantified the individual brain phospholipid metabolites from 15 cm(3) effective (8.0 cm(3) nominal) volumes from the left/right-parieto-occipital cortex and left/right thalamus in 10 normal volunteers. Individual constituents from the phosphomonoester (PME) region; phosphoethanolamine (PEth), phosphocholine (PCh) and the phosphodiester (PDE) region; glycerophosphoethanolamine (GPEth), glycerophosphocholine (GPCh) and membrane phospholipids (MP) were separately quantified to assess the precision of our method at 4 T against previous (1)H-decoupled (31)P-MRS brain studies at lower fields and much larger voxels. Derived concentrations (mM/l tissue) for PEth, PCh, GPEth, GPCh and MP in the left-parieto-occipital cortex were 0.81 +/- 0.21, 0.46 +/- 0.14, 0.74 +/- 0.30, 1.15 +/- 0.43 and 1.54 +/- 0.95 mM, respectively, and 0.94 +/- 0.16, 0.46 +/- 0.17, 0.83 +/- 0.22, 1.14 +/- 0.40 and 1.26 +/- 0.78 mM for the right parieto-occipital cortex. Derived concentrations (mM/l tissue) for PEth, PCh, GPEth, GPCh and MP in the left-thalamus were 0.69 +/- 0.18, 0.42 +/- 0.16, 0.63 +/- 0.20, 1.05 +/- 0.42 and 0.93 +/- 0.56 mM, respectively, and 0.68 +/- 0.24, 0.34 +/- 0.18, 0.60 +/- 0.23, 1.09 +/- 0.36 and 0.74 +/- 0.48 mM for the right-thalamus. This is the first study to our knowledge that has been able to quantify each of these individual phospholipid metabolites from such small voxels in the brain within a clinically reasonable scan time and without (1)H-decoupling or NOE." @default.
• W2003451199 created "2016-06-24" @default.
• W2003451199 creator A5012883431 @default.
• W2003451199 creator A5032740051 @default.
• W2003451199 creator A5049858309 @default.
• W2003451199 creator A5057436523 @default.
• W2003451199 date "2002-01-01" @default.
• W2003451199 modified "2023-10-17" @default.
• W2003451199 title "In vivo brain31P-MRS: measuring the phospholipid resonances at 4 Tesla from small voxels" @default.
• W2003451199 cites W1547168137 @default.
• W2003451199 cites W1964201164 @default.
• W2003451199 cites W1969436242 @default.
• W2003451199 cites W1974462060 @default.
• W2003451199 cites W1984756727 @default.
• W2003451199 cites W1985282676 @default.
• W2003451199 cites W1993853798 @default.
• W2003451199 cites W2010007978 @default.
• W2003451199 cites W2017725775 @default.
• W2003451199 cites W2021331185 @default.
• W2003451199 cites W2039238247 @default.
• W2003451199 cites W2041624772 @default.
• W2003451199 cites W2048516955 @default.
• W2003451199 cites W2060528621 @default.
• W2003451199 cites W2068108406 @default.
• W2003451199 cites W2069468777 @default.
• W2003451199 cites W2070115555 @default.
• W2003451199 cites W2078495335 @default.
• W2003451199 cites W2079385268 @default.
• W2003451199 cites W2080959570 @default.
• W2003451199 cites W2087153832 @default.
• W2003451199 cites W2089685769 @default.
• W2003451199 cites W2093212523 @default.
• W2003451199 cites W2109563420 @default.
• W2003451199 cites W2153816902 @default.
• W2003451199 cites W2170862212 @default.
• W2003451199 cites W2312453935 @default.
• W2003451199 cites W4244572478 @default.
• W2003451199 doi "https://doi.org/10.1002/nbm.776" @default.
• W2003451199 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12203225" @default.
• W2003451199 hasPublicationYear "2002" @default.
• W2003451199 type Work @default.
• W2003451199 sameAs 2003451199 @default.
• W2003451199 citedByCount "64" @default.
• W2003451199 countsByYear W20034511992012 @default.
• W2003451199 countsByYear W20034511992013 @default.
• W2003451199 countsByYear W20034511992014 @default.
• W2003451199 countsByYear W20034511992015 @default.
• W2003451199 countsByYear W20034511992016 @default.
• W2003451199 countsByYear W20034511992018 @default.
• W2003451199 countsByYear W20034511992020 @default.
• W2003451199 countsByYear W20034511992021 @default.
• W2003451199 countsByYear W20034511992022 @default.
• W2003451199 countsByYear W20034511992023 @default.
• W2003451199 crossrefType "journal-article" @default.
• W2003451199 hasAuthorship W2003451199A5012883431 @default.
• W2003451199 hasAuthorship W2003451199A5032740051 @default.
• W2003451199 hasAuthorship W2003451199A5049858309 @default.
• W2003451199 hasAuthorship W2003451199A5057436523 @default.
• W2003451199 hasConcept C121332964 @default.
• W2003451199 hasConcept C126838900 @default.
• W2003451199 hasConcept C169760540 @default.
• W2003451199 hasConcept C185592680 @default.
• W2003451199 hasConcept C2776330855 @default.
• W2003451199 hasConcept C2776923060 @default.
• W2003451199 hasConcept C2777348757 @default.
• W2003451199 hasConcept C2778918659 @default.
• W2003451199 hasConcept C41625074 @default.
• W2003451199 hasConcept C46141821 @default.
• W2003451199 hasConcept C54170458 @default.
• W2003451199 hasConcept C55493867 @default.
• W2003451199 hasConcept C71924100 @default.
• W2003451199 hasConcept C86803240 @default.
• W2003451199 hasConceptScore W2003451199C121332964 @default.
• W2003451199 hasConceptScore W2003451199C126838900 @default.
• W2003451199 hasConceptScore W2003451199C169760540 @default.
• W2003451199 hasConceptScore W2003451199C185592680 @default.
• W2003451199 hasConceptScore W2003451199C2776330855 @default.
• W2003451199 hasConceptScore W2003451199C2776923060 @default.
• W2003451199 hasConceptScore W2003451199C2777348757 @default.
• W2003451199 hasConceptScore W2003451199C2778918659 @default.
• W2003451199 hasConceptScore W2003451199C41625074 @default.
• W2003451199 hasConceptScore W2003451199C46141821 @default.
• W2003451199 hasConceptScore W2003451199C54170458 @default.
• W2003451199 hasConceptScore W2003451199C55493867 @default.
• W2003451199 hasConceptScore W2003451199C71924100 @default.
• W2003451199 hasConceptScore W2003451199C86803240 @default.
• W2003451199 hasIssue "5" @default.
• W2003451199 hasLocation W20034511991 @default.
• W2003451199 hasLocation W20034511992 @default.
• W2003451199 hasOpenAccess W2003451199 @default.
• W2003451199 hasPrimaryLocation W20034511991 @default.
• W2003451199 hasRelatedWork W1965990791 @default.
• W2003451199 hasRelatedWork W1966328705 @default.
• W2003451199 hasRelatedWork W1976772823 @default.
• W2003451199 hasRelatedWork W1979073481 @default.
• W2003451199 hasRelatedWork W2013650172 @default.
• W2003451199 hasRelatedWork W2021682846 @default.
• W2003451199 hasRelatedWork W2042917569 @default.

• next