Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003454982> ?p ?o ?g. }
- W2003454982 endingPage "26" @default.
- W2003454982 startingPage "18" @default.
- W2003454982 abstract "Psychological and physical stressors best exemplify the intercommunication of the immune and the nervous systems. It has been shown that stress significantly impacts leukocyte cellularity and immune responses and alters susceptibility to various diseases. While acute stress has been shown to enhance immune responses, chronic stress often leads to immunosuppression. Among many criteria examined upon exposure to chronic stress, the reduction in lymphocyte mitogenic response and lymphocyte cellularity are commonly assessed. We have reported that chronic restraint stress could induce lymphocyte reduction, an effect dependent on endogenous opioids. Interestingly, the effect of endogenous opioids was found to be exerted through increasing the expression of a cell death receptor, Fas, and an increased sensitivity of lymphocytes to apoptosis. Stress-induced lymphocyte reduction was not affected by adrenalectomy. In this review, based on available literature and our recent data, we will discuss the role of the hypothalamic-pituitary-adrenal axis and endogenous opioids and examine the mechanisms by which chronic stress modulates lymphocyte apoptosis." @default.
- W2003454982 created "2016-06-24" @default.
- W2003454982 creator A5009087892 @default.
- W2003454982 creator A5029437364 @default.
- W2003454982 creator A5060061088 @default.
- W2003454982 creator A5062682623 @default.
- W2003454982 creator A5065727282 @default.
- W2003454982 creator A5082257904 @default.
- W2003454982 date "2003-02-01" @default.
- W2003454982 modified "2023-10-18" @default.
- W2003454982 title "Stressed to death: Implication of lymphocyte apoptosis for psychoneuroimmunology" @default.
- W2003454982 cites W1515064408 @default.
- W2003454982 cites W1538345593 @default.
- W2003454982 cites W1571529930 @default.
- W2003454982 cites W1606295911 @default.
- W2003454982 cites W1661967651 @default.
- W2003454982 cites W1920167267 @default.
- W2003454982 cites W1964241765 @default.
- W2003454982 cites W1964518559 @default.
- W2003454982 cites W1965117083 @default.
- W2003454982 cites W1968248096 @default.
- W2003454982 cites W1972017211 @default.
- W2003454982 cites W1973792489 @default.
- W2003454982 cites W1977247384 @default.
- W2003454982 cites W1978062690 @default.
- W2003454982 cites W1985342460 @default.
- W2003454982 cites W1991915145 @default.
- W2003454982 cites W1992386229 @default.
- W2003454982 cites W1993983321 @default.
- W2003454982 cites W1997282991 @default.
- W2003454982 cites W1999216264 @default.
- W2003454982 cites W2000204883 @default.
- W2003454982 cites W2002733542 @default.
- W2003454982 cites W2003356209 @default.
- W2003454982 cites W2003501749 @default.
- W2003454982 cites W2004257203 @default.
- W2003454982 cites W2010645451 @default.
- W2003454982 cites W2012031475 @default.
- W2003454982 cites W2013074022 @default.
- W2003454982 cites W2015902645 @default.
- W2003454982 cites W2017663673 @default.
- W2003454982 cites W2018523904 @default.
- W2003454982 cites W2021941814 @default.
- W2003454982 cites W2024207873 @default.
- W2003454982 cites W2029234888 @default.
- W2003454982 cites W2030104393 @default.
- W2003454982 cites W2030411726 @default.
- W2003454982 cites W2033360952 @default.
- W2003454982 cites W2033362419 @default.
- W2003454982 cites W2036773924 @default.
- W2003454982 cites W2039470219 @default.
- W2003454982 cites W2048953132 @default.
- W2003454982 cites W2049026112 @default.
- W2003454982 cites W2054818875 @default.
- W2003454982 cites W2060203869 @default.
- W2003454982 cites W2060567554 @default.
- W2003454982 cites W2062200593 @default.
- W2003454982 cites W2065317641 @default.
- W2003454982 cites W2065413461 @default.
- W2003454982 cites W2069402089 @default.
- W2003454982 cites W2073242056 @default.
- W2003454982 cites W2076229621 @default.
- W2003454982 cites W2076779192 @default.
- W2003454982 cites W2081326101 @default.
- W2003454982 cites W2084609653 @default.
- W2003454982 cites W2090897194 @default.
- W2003454982 cites W2091694332 @default.
- W2003454982 cites W2094628847 @default.
- W2003454982 cites W2096715450 @default.
- W2003454982 cites W2117026081 @default.
- W2003454982 cites W2123807794 @default.
- W2003454982 cites W2124622759 @default.
- W2003454982 cites W2131608155 @default.
- W2003454982 cites W2132294734 @default.
- W2003454982 cites W2137577469 @default.
- W2003454982 cites W2137694849 @default.
- W2003454982 cites W2140955159 @default.
- W2003454982 cites W2147340819 @default.
- W2003454982 cites W2152213870 @default.
- W2003454982 cites W2159531745 @default.
- W2003454982 cites W2164859220 @default.
- W2003454982 cites W2175283437 @default.
- W2003454982 cites W2409378398 @default.
- W2003454982 cites W242053753 @default.
- W2003454982 cites W4240026283 @default.
- W2003454982 cites W4254983070 @default.
- W2003454982 cites W91705921 @default.
- W2003454982 cites W2010356459 @default.
- W2003454982 doi "https://doi.org/10.1016/s0889-1591(02)00062-4" @default.
- W2003454982 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12615182" @default.
- W2003454982 hasPublicationYear "2003" @default.
- W2003454982 type Work @default.
- W2003454982 sameAs 2003454982 @default.
- W2003454982 citedByCount "80" @default.
- W2003454982 countsByYear W20034549822012 @default.
- W2003454982 countsByYear W20034549822013 @default.
- W2003454982 countsByYear W20034549822014 @default.
- W2003454982 countsByYear W20034549822015 @default.