Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003459196> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2003459196 endingPage "499" @default.
- W2003459196 startingPage "491" @default.
- W2003459196 abstract "The median lethal dose (MLD) of a pathogenic strain of Yersinia pestis was established by three routes of administration in three strains of mouse. There was no significant difference between the MLDs in the different strains of mouse. The MLD by the subcutaneous route in BalbC and an outbred line was approximately 1 c.f.u.; the MLD following intraperitoneal administration was tenfold higher. There were significant differences in the mean times to death after administration of the challenge by different routes. The relative efficacy of a live attenuated vaccine strain of Y. pestis (EV76) was compared with that of the formaldehyde-killed vaccine (Plague vaccine, USP). EV76 protected against high challenge doses (up to 5.75 × 106 MLD), though immunized animals showed side effects of varying severity. The killed vaccine was less effective in terms of dose-protection (deaths occurred after challenge with 4000 MLD) and several of the vaccinated animals suffered sub-lethal, plague-related sequelae to the challenge." @default.
- W2003459196 created "2016-06-24" @default.
- W2003459196 creator A5007325636 @default.
- W2003459196 date "1981-01-01" @default.
- W2003459196 modified "2023-09-23" @default.
- W2003459196 title "Properties and pharmacological action of plague murine toxin" @default.
- W2003459196 cites W120336564 @default.
- W2003459196 cites W1518896112 @default.
- W2003459196 cites W1844758536 @default.
- W2003459196 cites W1942618335 @default.
- W2003459196 cites W1964781345 @default.
- W2003459196 cites W1967352779 @default.
- W2003459196 cites W1981456403 @default.
- W2003459196 cites W1987657681 @default.
- W2003459196 cites W1994289336 @default.
- W2003459196 cites W202219468 @default.
- W2003459196 cites W2042429093 @default.
- W2003459196 cites W2052443123 @default.
- W2003459196 cites W2075676530 @default.
- W2003459196 cites W2124100352 @default.
- W2003459196 cites W2157647835 @default.
- W2003459196 cites W2173978042 @default.
- W2003459196 cites W2187398641 @default.
- W2003459196 cites W2320825261 @default.
- W2003459196 cites W4247078028 @default.
- W2003459196 doi "https://doi.org/10.1016/0163-7258(81)90094-2" @default.
- W2003459196 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7025029" @default.
- W2003459196 hasPublicationYear "1981" @default.
- W2003459196 type Work @default.
- W2003459196 sameAs 2003459196 @default.
- W2003459196 citedByCount "19" @default.
- W2003459196 countsByYear W20034591962013 @default.
- W2003459196 countsByYear W20034591962014 @default.
- W2003459196 crossrefType "journal-article" @default.
- W2003459196 hasAuthorship W2003459196A5007325636 @default.
- W2003459196 hasConcept C104317684 @default.
- W2003459196 hasConcept C126322002 @default.
- W2003459196 hasConcept C142724271 @default.
- W2003459196 hasConcept C159047783 @default.
- W2003459196 hasConcept C167552308 @default.
- W2003459196 hasConcept C2776093070 @default.
- W2003459196 hasConcept C2777367657 @default.
- W2003459196 hasConcept C2777544843 @default.
- W2003459196 hasConcept C2778022156 @default.
- W2003459196 hasConcept C2778059882 @default.
- W2003459196 hasConcept C2778222588 @default.
- W2003459196 hasConcept C29730261 @default.
- W2003459196 hasConcept C33070731 @default.
- W2003459196 hasConcept C55493867 @default.
- W2003459196 hasConcept C60987743 @default.
- W2003459196 hasConcept C71924100 @default.
- W2003459196 hasConcept C86803240 @default.
- W2003459196 hasConcept C89423630 @default.
- W2003459196 hasConcept C98274493 @default.
- W2003459196 hasConceptScore W2003459196C104317684 @default.
- W2003459196 hasConceptScore W2003459196C126322002 @default.
- W2003459196 hasConceptScore W2003459196C142724271 @default.
- W2003459196 hasConceptScore W2003459196C159047783 @default.
- W2003459196 hasConceptScore W2003459196C167552308 @default.
- W2003459196 hasConceptScore W2003459196C2776093070 @default.
- W2003459196 hasConceptScore W2003459196C2777367657 @default.
- W2003459196 hasConceptScore W2003459196C2777544843 @default.
- W2003459196 hasConceptScore W2003459196C2778022156 @default.
- W2003459196 hasConceptScore W2003459196C2778059882 @default.
- W2003459196 hasConceptScore W2003459196C2778222588 @default.
- W2003459196 hasConceptScore W2003459196C29730261 @default.
- W2003459196 hasConceptScore W2003459196C33070731 @default.
- W2003459196 hasConceptScore W2003459196C55493867 @default.
- W2003459196 hasConceptScore W2003459196C60987743 @default.
- W2003459196 hasConceptScore W2003459196C71924100 @default.
- W2003459196 hasConceptScore W2003459196C86803240 @default.
- W2003459196 hasConceptScore W2003459196C89423630 @default.
- W2003459196 hasConceptScore W2003459196C98274493 @default.
- W2003459196 hasIssue "3" @default.
- W2003459196 hasLocation W20034591961 @default.
- W2003459196 hasLocation W20034591962 @default.
- W2003459196 hasOpenAccess W2003459196 @default.
- W2003459196 hasPrimaryLocation W20034591961 @default.
- W2003459196 hasRelatedWork W183030638 @default.
- W2003459196 hasRelatedWork W1978793659 @default.
- W2003459196 hasRelatedWork W1998030193 @default.
- W2003459196 hasRelatedWork W20920239 @default.
- W2003459196 hasRelatedWork W2125373518 @default.
- W2003459196 hasRelatedWork W2280863916 @default.
- W2003459196 hasRelatedWork W2327450496 @default.
- W2003459196 hasRelatedWork W2341013520 @default.
- W2003459196 hasRelatedWork W2414768477 @default.
- W2003459196 hasRelatedWork W5409190 @default.
- W2003459196 hasVolume "12" @default.
- W2003459196 isParatext "false" @default.
- W2003459196 isRetracted "false" @default.
- W2003459196 magId "2003459196" @default.
- W2003459196 workType "article" @default.