FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003459734> ?p ?o ?g. }

• W2003459734 endingPage "1623" @default.
• W2003459734 startingPage "1615" @default.
• W2003459734 abstract "We report here about the relationship between the destabilization of the lipid organization induced by praziquantel and derivatives and their mode of insertion into the lipid matrix. Measurements of lipid transition temperature and efflux of 6-carboxyfluorescein encapsulated in liposomes establish the lipid destabilizing capacity of praziquantel as compared to praziquantel derivatives. IR spectroscopy (attenuated total reflection technique) applied to oriented lipid bilayers indicates that praziquantel or derivatives do not modify significantly the lipid structure. In order to give a molecular description of the position of the drug into the lipid bilayer, we applied a conformational analysis procedure making it possible to calculate the structure of amphiphilic molecules assembled in aggregates and the mode of insertion of amphiphilic drugs into a lipid layer. The praziquantel lipid destabilizing capacity is explained in terms of the high praziquantel-lipid interaction and the large area occupied per drug molecule in the lipid layer." @default.
• W2003459734 created "2016-06-24" @default.
• W2003459734 creator A5000980598 @default.
• W2003459734 creator A5012395286 @default.
• W2003459734 creator A5023233738 @default.
• W2003459734 creator A5050533193 @default.
• W2003459734 creator A5060600820 @default.
• W2003459734 date "1988-04-01" @default.
• W2003459734 modified "2023-10-01" @default.
• W2003459734 title "Mode of insertion of praziquantel and derivatives into lipid membranes" @default.
• W2003459734 cites W1534025508 @default.
• W2003459734 cites W1549258404 @default.
• W2003459734 cites W1993816034 @default.
• W2003459734 cites W1995440582 @default.
• W2003459734 cites W2016170602 @default.
• W2003459734 cites W2025883388 @default.
• W2003459734 cites W2044566030 @default.
• W2003459734 cites W2054873814 @default.
• W2003459734 cites W2061866123 @default.
• W2003459734 cites W2064997365 @default.
• W2003459734 cites W2075736809 @default.
• W2003459734 cites W2085631553 @default.
• W2003459734 cites W2094906575 @default.
• W2003459734 cites W2095176630 @default.
• W2003459734 cites W2171074980 @default.
• W2003459734 cites W2315475510 @default.
• W2003459734 cites W2332732631 @default.
• W2003459734 cites W4211145066 @default.
• W2003459734 doi "https://doi.org/10.1016/0006-2952(88)90026-3" @default.
• W2003459734 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3358791" @default.
• W2003459734 hasPublicationYear "1988" @default.
• W2003459734 type Work @default.
• W2003459734 sameAs 2003459734 @default.
• W2003459734 citedByCount "38" @default.
• W2003459734 countsByYear W20034597342012 @default.
• W2003459734 countsByYear W20034597342013 @default.
• W2003459734 countsByYear W20034597342015 @default.
• W2003459734 countsByYear W20034597342016 @default.
• W2003459734 countsByYear W20034597342017 @default.
• W2003459734 countsByYear W20034597342019 @default.
• W2003459734 countsByYear W20034597342020 @default.
• W2003459734 countsByYear W20034597342022 @default.
• W2003459734 crossrefType "journal-article" @default.
• W2003459734 hasAuthorship W2003459734A5000980598 @default.
• W2003459734 hasAuthorship W2003459734A5012395286 @default.
• W2003459734 hasAuthorship W2003459734A5023233738 @default.
• W2003459734 hasAuthorship W2003459734A5050533193 @default.
• W2003459734 hasAuthorship W2003459734A5060600820 @default.
• W2003459734 hasConcept C12554922 @default.
• W2003459734 hasConcept C15920480 @default.
• W2003459734 hasConcept C165901193 @default.
• W2003459734 hasConcept C178790620 @default.
• W2003459734 hasConcept C185154212 @default.
• W2003459734 hasConcept C185592680 @default.
• W2003459734 hasConcept C192157962 @default.
• W2003459734 hasConcept C203014093 @default.
• W2003459734 hasConcept C2776225656 @default.
• W2003459734 hasConcept C2779744950 @default.
• W2003459734 hasConcept C32909587 @default.
• W2003459734 hasConcept C39944091 @default.
• W2003459734 hasConcept C41625074 @default.
• W2003459734 hasConcept C521977710 @default.
• W2003459734 hasConcept C55493867 @default.
• W2003459734 hasConcept C67407626 @default.
• W2003459734 hasConcept C71240020 @default.
• W2003459734 hasConcept C76564549 @default.
• W2003459734 hasConcept C86803240 @default.
• W2003459734 hasConceptScore W2003459734C12554922 @default.
• W2003459734 hasConceptScore W2003459734C15920480 @default.
• W2003459734 hasConceptScore W2003459734C165901193 @default.
• W2003459734 hasConceptScore W2003459734C178790620 @default.
• W2003459734 hasConceptScore W2003459734C185154212 @default.
• W2003459734 hasConceptScore W2003459734C185592680 @default.
• W2003459734 hasConceptScore W2003459734C192157962 @default.
• W2003459734 hasConceptScore W2003459734C203014093 @default.
• W2003459734 hasConceptScore W2003459734C2776225656 @default.
• W2003459734 hasConceptScore W2003459734C2779744950 @default.
• W2003459734 hasConceptScore W2003459734C32909587 @default.
• W2003459734 hasConceptScore W2003459734C39944091 @default.
• W2003459734 hasConceptScore W2003459734C41625074 @default.
• W2003459734 hasConceptScore W2003459734C521977710 @default.
• W2003459734 hasConceptScore W2003459734C55493867 @default.
• W2003459734 hasConceptScore W2003459734C67407626 @default.
• W2003459734 hasConceptScore W2003459734C71240020 @default.
• W2003459734 hasConceptScore W2003459734C76564549 @default.
• W2003459734 hasConceptScore W2003459734C86803240 @default.
• W2003459734 hasIssue "8" @default.
• W2003459734 hasLocation W20034597341 @default.
• W2003459734 hasLocation W20034597342 @default.
• W2003459734 hasOpenAccess W2003459734 @default.
• W2003459734 hasPrimaryLocation W20034597341 @default.
• W2003459734 hasRelatedWork W1990199411 @default.
• W2003459734 hasRelatedWork W2004998570 @default.
• W2003459734 hasRelatedWork W2026073350 @default.
• W2003459734 hasRelatedWork W2044693202 @default.
• W2003459734 hasRelatedWork W2278025227 @default.
• W2003459734 hasRelatedWork W2324918440 @default.
• W2003459734 hasRelatedWork W2594002376 @default.

• next