FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003476486> ?p ?o ?g. }

• W2003476486 endingPage "737" @default.
• W2003476486 startingPage "730" @default.
• W2003476486 abstract "Sjögren's syndrome is an autoimmune disease affecting the exocrine glands; it is thought to result from T-cell-mediated damage. In the labial glands of 20 patients with Sjögren's syndrome, infiltrating T cells were immunohistochemically characterized, and T-cell receptor (TCR) gene expression was examined with a method based on polymerase chain reaction. Most of these lymphocytes expressed CD3, CD4, CD45RO, and TCRαβ, whereas less than 5% of them expressed CD25 and CD69. The TCR Vα and Vβ genes expressed in peripheral blood mononuclear cells were diverse, whereas the TCR Vα and Vβ repertoires in the labial glands were more restricted but were still heterogeneous. The predominantly used Vα and Vβ families in the labial glands, when compared with those in peripheral blood mononuclear cells, were found to vary in individual patients and also to differ from patient to patient. Thus the T-cell population in the labial glands was polyclonal but showed a more restricted pattern than that seen in peripheral blood mononuclear cells. Sjögren's syndrome is an autoimmune disease affecting the exocrine glands; it is thought to result from T-cell-mediated damage. In the labial glands of 20 patients with Sjögren's syndrome, infiltrating T cells were immunohistochemically characterized, and T-cell receptor (TCR) gene expression was examined with a method based on polymerase chain reaction. Most of these lymphocytes expressed CD3, CD4, CD45RO, and TCRαβ, whereas less than 5% of them expressed CD25 and CD69. The TCR Vα and Vβ genes expressed in peripheral blood mononuclear cells were diverse, whereas the TCR Vα and Vβ repertoires in the labial glands were more restricted but were still heterogeneous. The predominantly used Vα and Vβ families in the labial glands, when compared with those in peripheral blood mononuclear cells, were found to vary in individual patients and also to differ from patient to patient. Thus the T-cell population in the labial glands was polyclonal but showed a more restricted pattern than that seen in peripheral blood mononuclear cells." @default.
• W2003476486 created "2016-06-24" @default.
• W2003476486 creator A5008480678 @default.
• W2003476486 creator A5009325297 @default.
• W2003476486 creator A5012066844 @default.
• W2003476486 creator A5014270152 @default.
• W2003476486 creator A5031836628 @default.
• W2003476486 creator A5032549835 @default.
• W2003476486 creator A5085142320 @default.
• W2003476486 date "1995-06-01" @default.
• W2003476486 modified "2023-10-15" @default.
• W2003476486 title "T-cell receptor Vα and Vβ gene use by infiltrating T cells in labial glands of patients with Sjögren's syndrome" @default.
• W2003476486 cites W1558221257 @default.
• W2003476486 cites W1599545720 @default.
• W2003476486 cites W1610023233 @default.
• W2003476486 cites W1965559674 @default.
• W2003476486 cites W1968164935 @default.
• W2003476486 cites W1973210432 @default.
• W2003476486 cites W1982917969 @default.
• W2003476486 cites W1993733461 @default.
• W2003476486 cites W1998531275 @default.
• W2003476486 cites W2004989086 @default.
• W2003476486 cites W2008647959 @default.
• W2003476486 cites W2015508829 @default.
• W2003476486 cites W2016096642 @default.
• W2003476486 cites W2016792965 @default.
• W2003476486 cites W2019238917 @default.
• W2003476486 cites W2021951643 @default.
• W2003476486 cites W2028093567 @default.
• W2003476486 cites W2040113869 @default.
• W2003476486 cites W2044316391 @default.
• W2003476486 cites W2050062252 @default.
• W2003476486 cites W2053840189 @default.
• W2003476486 cites W2071743575 @default.
• W2003476486 cites W2087939306 @default.
• W2003476486 cites W2088477504 @default.
• W2003476486 cites W2113161608 @default.
• W2003476486 cites W2117420131 @default.
• W2003476486 cites W2120773157 @default.
• W2003476486 cites W2123517465 @default.
• W2003476486 cites W2126527831 @default.
• W2003476486 cites W4294216491 @default.
• W2003476486 doi "https://doi.org/10.1016/s1079-2104(05)80308-7" @default.
• W2003476486 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7621031" @default.
• W2003476486 hasPublicationYear "1995" @default.
• W2003476486 type Work @default.
• W2003476486 sameAs 2003476486 @default.
• W2003476486 citedByCount "23" @default.
• W2003476486 countsByYear W20034764862012 @default.
• W2003476486 countsByYear W20034764862016 @default.
• W2003476486 countsByYear W20034764862017 @default.
• W2003476486 countsByYear W20034764862018 @default.
• W2003476486 countsByYear W20034764862022 @default.
• W2003476486 crossrefType "journal-article" @default.
• W2003476486 hasAuthorship W2003476486A5008480678 @default.
• W2003476486 hasAuthorship W2003476486A5009325297 @default.
• W2003476486 hasAuthorship W2003476486A5012066844 @default.
• W2003476486 hasAuthorship W2003476486A5014270152 @default.
• W2003476486 hasAuthorship W2003476486A5031836628 @default.
• W2003476486 hasAuthorship W2003476486A5032549835 @default.
• W2003476486 hasAuthorship W2003476486A5085142320 @default.
• W2003476486 hasConcept C114684123 @default.
• W2003476486 hasConcept C134018914 @default.
• W2003476486 hasConcept C137061746 @default.
• W2003476486 hasConcept C142724271 @default.
• W2003476486 hasConcept C147483822 @default.
• W2003476486 hasConcept C153911025 @default.
• W2003476486 hasConcept C159654299 @default.
• W2003476486 hasConcept C167672396 @default.
• W2003476486 hasConcept C19317047 @default.
• W2003476486 hasConcept C202751555 @default.
• W2003476486 hasConcept C203014093 @default.
• W2003476486 hasConcept C2776090121 @default.
• W2003476486 hasConcept C2778214642 @default.
• W2003476486 hasConcept C2779075594 @default.
• W2003476486 hasConcept C49039625 @default.
• W2003476486 hasConcept C55493867 @default.
• W2003476486 hasConcept C71924100 @default.
• W2003476486 hasConcept C79484868 @default.
• W2003476486 hasConcept C86803240 @default.
• W2003476486 hasConcept C8891405 @default.
• W2003476486 hasConceptScore W2003476486C114684123 @default.
• W2003476486 hasConceptScore W2003476486C134018914 @default.
• W2003476486 hasConceptScore W2003476486C137061746 @default.
• W2003476486 hasConceptScore W2003476486C142724271 @default.
• W2003476486 hasConceptScore W2003476486C147483822 @default.
• W2003476486 hasConceptScore W2003476486C153911025 @default.
• W2003476486 hasConceptScore W2003476486C159654299 @default.
• W2003476486 hasConceptScore W2003476486C167672396 @default.
• W2003476486 hasConceptScore W2003476486C19317047 @default.
• W2003476486 hasConceptScore W2003476486C202751555 @default.
• W2003476486 hasConceptScore W2003476486C203014093 @default.
• W2003476486 hasConceptScore W2003476486C2776090121 @default.
• W2003476486 hasConceptScore W2003476486C2778214642 @default.
• W2003476486 hasConceptScore W2003476486C2779075594 @default.
• W2003476486 hasConceptScore W2003476486C49039625 @default.
• W2003476486 hasConceptScore W2003476486C55493867 @default.
• W2003476486 hasConceptScore W2003476486C71924100 @default.

• next