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- W2003481851 abstract "In three patients acute arthritis developed during the course of generalized herpes virus infections. Two patients with no known immunologic impairment had disseminated herpes simplex disease, and one patient, a renal transplant recipient, had cytomegalovirus infection. Patient 1 presented with diffuse vesicular rash and a painful, swollen right knee. Herpes simplex type 1 was isolated from vesicles present on the chest and in synovial fluid from the right knee. Patient 2 presented with right ankle pain and swelling, sore throat, fever and a diffuse vesicular rash. Herpes simplex type 1 was isolated from vesicles on the arms and chest and from a throat culture. The joint disease subsided within two weeks in Patient 1, and four months in Patient 2. In Patient 3 fever, and right hip and knee pain developed as well as urinary retention three months following renal transplantation. The right knee was erythematous, warm and swollen. Cytomegalovirus was isolated from the synovial fluid in the right knee, buffy coat, urine and throat cultures, and viral-like particles were seen within synovial fluid cells by electron microscopy. This patient died without resolution of the joint disease. The demonstration of acute arthritis during herpes simplex virus and cytomegalovirus infection adds a newly recognized feature to the protean manifestations of these viral infections and enlarges the spectrum of viral agents known to be associated with arthritis." @default.
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- W2003481851 date "1980-08-01" @default.
- W2003481851 modified "2023-10-12" @default.
- W2003481851 title "Acute monoarticular arthritis caused by herpes simplex virus and cytomegalovirus" @default.
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- W2003481851 doi "https://doi.org/10.1016/0002-9343(80)90384-8" @default.
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