Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003530632> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2003530632 endingPage "315" @default.
- W2003530632 startingPage "311" @default.
- W2003530632 abstract "Binding sites with high affinity and specificity for [3H]quinuclidinyl benzilate (QNB), a cholinergic muscarinic receptor antagonist, were found in homogenates of rat urinary bladder. Atropine and scopolamine inhibited 50% of the specifically bound [3H]QNB (IC50) at a concentration of approximately 2 nM, whereas the agonist oxotremorine had an IC50 of 580 nM. By contrast, the IC50 for the ganglionic nicotinic antagonist mecamylamine was greater than 100,000 nM. These values are similar to those reported for [3H]QNB binding sites in rat brain. [3H]QNB binding was characterized in rat bladder obtained from animals aged 6, 16, and 26 months. No differences in either the number of binding sites or the affinity constant for the radioligand were noted between these groups, suggesting that there are no agerelated alterations in muscarinic receptor recognition sites in this organ." @default.
- W2003530632 created "2016-06-24" @default.
- W2003530632 creator A5012511945 @default.
- W2003530632 creator A5033429093 @default.
- W2003530632 creator A5073075260 @default.
- W2003530632 date "1983-01-01" @default.
- W2003530632 modified "2023-09-25" @default.
- W2003530632 title "The effect of aging on cholinergic receptor binding in the rat urinary bladder" @default.
- W2003530632 cites W1775749144 @default.
- W2003530632 cites W1963792742 @default.
- W2003530632 cites W1970179449 @default.
- W2003530632 cites W1983649348 @default.
- W2003530632 cites W1995502143 @default.
- W2003530632 cites W1995994070 @default.
- W2003530632 cites W2003814102 @default.
- W2003530632 cites W2059141201 @default.
- W2003530632 cites W2061742018 @default.
- W2003530632 cites W2115250531 @default.
- W2003530632 cites W2414531089 @default.
- W2003530632 cites W2884698769 @default.
- W2003530632 doi "https://doi.org/10.1002/nau.1930020407" @default.
- W2003530632 hasPublicationYear "1983" @default.
- W2003530632 type Work @default.
- W2003530632 sameAs 2003530632 @default.
- W2003530632 citedByCount "11" @default.
- W2003530632 countsByYear W20035306322012 @default.
- W2003530632 crossrefType "journal-article" @default.
- W2003530632 hasAuthorship W2003530632A5012511945 @default.
- W2003530632 hasAuthorship W2003530632A5033429093 @default.
- W2003530632 hasAuthorship W2003530632A5073075260 @default.
- W2003530632 hasConcept C107824862 @default.
- W2003530632 hasConcept C126322002 @default.
- W2003530632 hasConcept C134018914 @default.
- W2003530632 hasConcept C170493617 @default.
- W2003530632 hasConcept C185592680 @default.
- W2003530632 hasConcept C188987157 @default.
- W2003530632 hasConcept C22885893 @default.
- W2003530632 hasConcept C2775859210 @default.
- W2003530632 hasConcept C2776723954 @default.
- W2003530632 hasConcept C2776880047 @default.
- W2003530632 hasConcept C2776885963 @default.
- W2003530632 hasConcept C2778824757 @default.
- W2003530632 hasConcept C2778938600 @default.
- W2003530632 hasConcept C2779762690 @default.
- W2003530632 hasConcept C2908651707 @default.
- W2003530632 hasConcept C33789571 @default.
- W2003530632 hasConcept C55493867 @default.
- W2003530632 hasConcept C67847695 @default.
- W2003530632 hasConcept C71924100 @default.
- W2003530632 hasConceptScore W2003530632C107824862 @default.
- W2003530632 hasConceptScore W2003530632C126322002 @default.
- W2003530632 hasConceptScore W2003530632C134018914 @default.
- W2003530632 hasConceptScore W2003530632C170493617 @default.
- W2003530632 hasConceptScore W2003530632C185592680 @default.
- W2003530632 hasConceptScore W2003530632C188987157 @default.
- W2003530632 hasConceptScore W2003530632C22885893 @default.
- W2003530632 hasConceptScore W2003530632C2775859210 @default.
- W2003530632 hasConceptScore W2003530632C2776723954 @default.
- W2003530632 hasConceptScore W2003530632C2776880047 @default.
- W2003530632 hasConceptScore W2003530632C2776885963 @default.
- W2003530632 hasConceptScore W2003530632C2778824757 @default.
- W2003530632 hasConceptScore W2003530632C2778938600 @default.
- W2003530632 hasConceptScore W2003530632C2779762690 @default.
- W2003530632 hasConceptScore W2003530632C2908651707 @default.
- W2003530632 hasConceptScore W2003530632C33789571 @default.
- W2003530632 hasConceptScore W2003530632C55493867 @default.
- W2003530632 hasConceptScore W2003530632C67847695 @default.
- W2003530632 hasConceptScore W2003530632C71924100 @default.
- W2003530632 hasIssue "4" @default.
- W2003530632 hasLocation W20035306321 @default.
- W2003530632 hasOpenAccess W2003530632 @default.
- W2003530632 hasPrimaryLocation W20035306321 @default.
- W2003530632 hasRelatedWork W1923333584 @default.
- W2003530632 hasRelatedWork W2003530632 @default.
- W2003530632 hasRelatedWork W2025991332 @default.
- W2003530632 hasRelatedWork W2071551266 @default.
- W2003530632 hasRelatedWork W2081147067 @default.
- W2003530632 hasRelatedWork W2081320142 @default.
- W2003530632 hasRelatedWork W2083922834 @default.
- W2003530632 hasRelatedWork W2115250531 @default.
- W2003530632 hasRelatedWork W2417174768 @default.
- W2003530632 hasRelatedWork W187282814 @default.
- W2003530632 hasVolume "2" @default.
- W2003530632 isParatext "false" @default.
- W2003530632 isRetracted "false" @default.
- W2003530632 magId "2003530632" @default.
- W2003530632 workType "article" @default.