Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003548652> ?p ?o ?g. }
- W2003548652 endingPage "99" @default.
- W2003548652 startingPage "90" @default.
- W2003548652 abstract "Recent reports have suggested that orexins, also known as hypocretins, play an important role in the modulation of respiratory control in mammals, but there are no data available describing the role of the orexinergic system in the peripheral and central chemoreception of non-mammalian vertebrates. Therefore, the present study was designed to examine the localization of orexin-immunoreactive neurons in the brain of toads (Rhinella schneideri) and to investigate the contribution of orexin receptor-1 (OX1R) to the hypoxic and hypercarbic ventilatory responses of these animals during light and dark phases. Our results demonstrated that the orexinergic neurons of R. schneideri are located in the suprachiasmatic nucleus of the diencephalon. Additionally, the intracerebroventricular injection of SB-334867 (OX1R selective antagonist) attenuated the ventilatory response to hypercarbia during the dark phase by acting on tidal volume and breathing frequency, while during the light phase, SB-334867 attenuated the ventilatory response to hypoxia by acting on tidal volume only. We conclude that in the toad R. schneideri, orexinergic neurons are located in the suprachiasmatic nucleus and that OX1R contributes to hypercarbic and hypoxic chemoreflexes." @default.
- W2003548652 created "2016-06-24" @default.
- W2003548652 creator A5000194947 @default.
- W2003548652 creator A5029649532 @default.
- W2003548652 creator A5039698330 @default.
- W2003548652 creator A5085561355 @default.
- W2003548652 date "2016-04-01" @default.
- W2003548652 modified "2023-10-18" @default.
- W2003548652 title "Orexin in the toad Rhinella schneideri: The location of orexinergic neurons and the role of orexin in ventilatory responses to hypercarbia and hypoxia" @default.
- W2003548652 cites W1484259031 @default.
- W2003548652 cites W1484997088 @default.
- W2003548652 cites W151111574 @default.
- W2003548652 cites W1627229807 @default.
- W2003548652 cites W1965055739 @default.
- W2003548652 cites W1965872583 @default.
- W2003548652 cites W1975787367 @default.
- W2003548652 cites W1978656148 @default.
- W2003548652 cites W1980264074 @default.
- W2003548652 cites W1990953173 @default.
- W2003548652 cites W1997541372 @default.
- W2003548652 cites W1998187085 @default.
- W2003548652 cites W2007105648 @default.
- W2003548652 cites W2012304873 @default.
- W2003548652 cites W2012934518 @default.
- W2003548652 cites W2019464797 @default.
- W2003548652 cites W2020056002 @default.
- W2003548652 cites W2024348439 @default.
- W2003548652 cites W2024364379 @default.
- W2003548652 cites W2025651646 @default.
- W2003548652 cites W2027740042 @default.
- W2003548652 cites W2033571311 @default.
- W2003548652 cites W2036325467 @default.
- W2003548652 cites W2039184458 @default.
- W2003548652 cites W2042179780 @default.
- W2003548652 cites W2046716099 @default.
- W2003548652 cites W2049082572 @default.
- W2003548652 cites W2056020598 @default.
- W2003548652 cites W2067712019 @default.
- W2003548652 cites W2067872050 @default.
- W2003548652 cites W2070006613 @default.
- W2003548652 cites W2071544976 @default.
- W2003548652 cites W2075627078 @default.
- W2003548652 cites W2085712847 @default.
- W2003548652 cites W2088537924 @default.
- W2003548652 cites W2095329930 @default.
- W2003548652 cites W2098176043 @default.
- W2003548652 cites W2100743305 @default.
- W2003548652 cites W2102111460 @default.
- W2003548652 cites W2103415266 @default.
- W2003548652 cites W2113440620 @default.
- W2003548652 cites W2116488454 @default.
- W2003548652 cites W2121945202 @default.
- W2003548652 cites W2129451654 @default.
- W2003548652 cites W2129491952 @default.
- W2003548652 cites W2130717252 @default.
- W2003548652 cites W2148913502 @default.
- W2003548652 cites W2150132984 @default.
- W2003548652 cites W2152211310 @default.
- W2003548652 cites W2163737374 @default.
- W2003548652 cites W2344181987 @default.
- W2003548652 cites W2405221596 @default.
- W2003548652 cites W56856045 @default.
- W2003548652 doi "https://doi.org/10.1016/j.resp.2014.11.014" @default.
- W2003548652 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25434286" @default.
- W2003548652 hasPublicationYear "2016" @default.
- W2003548652 type Work @default.
- W2003548652 sameAs 2003548652 @default.
- W2003548652 citedByCount "9" @default.
- W2003548652 countsByYear W20035486522016 @default.
- W2003548652 countsByYear W20035486522018 @default.
- W2003548652 countsByYear W20035486522019 @default.
- W2003548652 countsByYear W20035486522020 @default.
- W2003548652 countsByYear W20035486522021 @default.
- W2003548652 countsByYear W20035486522022 @default.
- W2003548652 countsByYear W20035486522023 @default.
- W2003548652 crossrefType "journal-article" @default.
- W2003548652 hasAuthorship W2003548652A5000194947 @default.
- W2003548652 hasAuthorship W2003548652A5029649532 @default.
- W2003548652 hasAuthorship W2003548652A5039698330 @default.
- W2003548652 hasAuthorship W2003548652A5085561355 @default.
- W2003548652 hasConcept C118303440 @default.
- W2003548652 hasConcept C126322002 @default.
- W2003548652 hasConcept C134018914 @default.
- W2003548652 hasConcept C169760540 @default.
- W2003548652 hasConcept C170493617 @default.
- W2003548652 hasConcept C178790620 @default.
- W2003548652 hasConcept C185592680 @default.
- W2003548652 hasConcept C2775969318 @default.
- W2003548652 hasConcept C2777003273 @default.
- W2003548652 hasConcept C2778166480 @default.
- W2003548652 hasConcept C2778553927 @default.
- W2003548652 hasConcept C2779317972 @default.
- W2003548652 hasConcept C2779680196 @default.
- W2003548652 hasConcept C2780714764 @default.
- W2003548652 hasConcept C2909479059 @default.
- W2003548652 hasConcept C2910823151 @default.
- W2003548652 hasConcept C540031477 @default.
- W2003548652 hasConcept C71924100 @default.