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- W2003562021 abstract "The recently discovered peptide urocortin-I, which is present in animal and human blood, is elevated in subjects with heart failure. In an experimental animal heart-failure model, urocortin-I had a sustained and beneficial effect on haemodynamic, endocrine and renal parameters. Urocortins (UCN) I, II and III have also been shown to prevent cell death when administered to primary cardiac myocyte cultures before or even after ischemic injury. This raises the possibility of using the urocortin family of peptides or urocortin-like agonists in the therapy of heart failure and as cardioprotective agents." @default.
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- W2003562021 date "2004-10-01" @default.
- W2003562021 modified "2023-10-16" @default.
- W2003562021 title "Urocortin in cardiovascular disease: pathophysiology and therapeutic potential" @default.
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- W2003562021 doi "https://doi.org/10.1016/j.ddstr.2004.08.007" @default.
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