FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003626688> ?p ?o ?g. }

• W2003626688 endingPage "6964" @default.
• W2003626688 startingPage "6954" @default.
• W2003626688 abstract "ABSTRACT Genetic characterization was performed for 10 group I Clostridium botulinum strains isolated from botulism cases in Japan between 2006 and 2011. Of these, 1 was type A, 2 were type B, and 7 were type A(B) {carrying a silent bont / B [ bont / (B) ] gene} serotype strains, based on botulinum neurotoxin (BoNT) production. The type A strain harbored the subtype A1 BoNT gene ( bont / A1 ), which is associated with the ha gene cluster. The type B strains carried bont / B5 or bont / B6 subtype genes. The type A(B) strains carried bont / A1 identical to that of type A(B) strain NCTC2916. However, bont / (B) genes in these strains showed single-nucleotide polymorphisms (SNPs) among strains. SNPs at 2 nucleotide positions of bont / (B) enabled classification of the type A(B) strains into 3 groups. Pulsed-field gel electrophoresis (PFGE) and multiple-locus variable-number tandem-repeat analysis (MLVA) also provided consistent separation results. In addition, the type A(B) strains were separated into 2 lineages based on their plasmid profiles. One lineage carried a small plasmid (5.9 kb), and another harbored 21-kb plasmids. To obtain more detailed genetic information about the 10 strains, we sequenced their genomes and compared them with 13 group I C. botulinum genomes in a database using whole-genome SNP analysis. This analysis provided high-resolution strain discrimination and enabled us to generate a refined phylogenetic tree that provides effective traceability of botulism cases, as well as bioterrorism materials. In the phylogenetic tree, the subtype B6 strains, Okayama2011 and Osaka05, were distantly separated from the other strains, indicating genomic divergence of subtype B6 strains among group I strains." @default.
• W2003626688 created "2016-06-24" @default.
• W2003626688 creator A5026878477 @default.
• W2003626688 creator A5050341079 @default.
• W2003626688 creator A5053108028 @default.
• W2003626688 creator A5054880833 @default.
• W2003626688 creator A5062026602 @default.
• W2003626688 creator A5062077739 @default.
• W2003626688 creator A5062642490 @default.
• W2003626688 creator A5077934644 @default.
• W2003626688 creator A5084126478 @default.
• W2003626688 creator A5088323724 @default.
• W2003626688 date "2014-11-15" @default.
• W2003626688 modified "2023-10-15" @default.
• W2003626688 title "Genetic Characterization and Comparison of Clostridium botulinum Isolates from Botulism Cases in Japan between 2006 and 2011" @default.
• W2003626688 cites W1483437518 @default.
• W2003626688 cites W1525284140 @default.
• W2003626688 cites W1528622602 @default.
• W2003626688 cites W1563585372 @default.
• W2003626688 cites W1805929641 @default.
• W2003626688 cites W1968279876 @default.
• W2003626688 cites W1969789782 @default.
• W2003626688 cites W1971028747 @default.
• W2003626688 cites W1973218548 @default.
• W2003626688 cites W1990770950 @default.
• W2003626688 cites W1994026714 @default.
• W2003626688 cites W1995508818 @default.
• W2003626688 cites W1998258963 @default.
• W2003626688 cites W2006762969 @default.
• W2003626688 cites W2013351499 @default.
• W2003626688 cites W2021232562 @default.
• W2003626688 cites W2024995596 @default.
• W2003626688 cites W2027872729 @default.
• W2003626688 cites W2040988277 @default.
• W2003626688 cites W2065909915 @default.
• W2003626688 cites W2078122171 @default.
• W2003626688 cites W2080475115 @default.
• W2003626688 cites W2083978706 @default.
• W2003626688 cites W2085135960 @default.
• W2003626688 cites W2096738649 @default.
• W2003626688 cites W2101211619 @default.
• W2003626688 cites W2108780469 @default.
• W2003626688 cites W2111510216 @default.
• W2003626688 cites W2112113834 @default.
• W2003626688 cites W2113755409 @default.
• W2003626688 cites W2119231718 @default.
• W2003626688 cites W2123599153 @default.
• W2003626688 cites W2126213235 @default.
• W2003626688 cites W2128777196 @default.
• W2003626688 cites W2132973687 @default.
• W2003626688 cites W2133479189 @default.
• W2003626688 cites W2133895941 @default.
• W2003626688 cites W2134455425 @default.
• W2003626688 cites W2136239379 @default.
• W2003626688 cites W2137889830 @default.
• W2003626688 cites W2141006452 @default.
• W2003626688 cites W2150131459 @default.
• W2003626688 cites W2154703885 @default.
• W2003626688 cites W2161815151 @default.
• W2003626688 cites W2165833997 @default.
• W2003626688 cites W2166228597 @default.
• W2003626688 cites W2166808362 @default.
• W2003626688 cites W2168696662 @default.
• W2003626688 cites W2325556576 @default.
• W2003626688 cites W4238831315 @default.
• W2003626688 cites W4247053599 @default.
• W2003626688 cites W4252071217 @default.
• W2003626688 doi "https://doi.org/10.1128/aem.02134-14" @default.
• W2003626688 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4249013" @default.
• W2003626688 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25192986" @default.
• W2003626688 hasPublicationYear "2014" @default.
• W2003626688 type Work @default.
• W2003626688 sameAs 2003626688 @default.
• W2003626688 citedByCount "23" @default.
• W2003626688 countsByYear W20036266882015 @default.
• W2003626688 countsByYear W20036266882016 @default.
• W2003626688 countsByYear W20036266882017 @default.
• W2003626688 countsByYear W20036266882018 @default.
• W2003626688 countsByYear W20036266882019 @default.
• W2003626688 countsByYear W20036266882020 @default.
• W2003626688 countsByYear W20036266882021 @default.
• W2003626688 countsByYear W20036266882022 @default.
• W2003626688 crossrefType "journal-article" @default.
• W2003626688 hasAuthorship W2003626688A5026878477 @default.
• W2003626688 hasAuthorship W2003626688A5050341079 @default.
• W2003626688 hasAuthorship W2003626688A5053108028 @default.
• W2003626688 hasAuthorship W2003626688A5054880833 @default.
• W2003626688 hasAuthorship W2003626688A5062026602 @default.
• W2003626688 hasAuthorship W2003626688A5062077739 @default.
• W2003626688 hasAuthorship W2003626688A5062642490 @default.
• W2003626688 hasAuthorship W2003626688A5077934644 @default.
• W2003626688 hasAuthorship W2003626688A5084126478 @default.
• W2003626688 hasAuthorship W2003626688A5088323724 @default.
• W2003626688 hasBestOaLocation W20036266881 @default.
• W2003626688 hasConcept C10389963 @default.
• W2003626688 hasConcept C104317684 @default.
• W2003626688 hasConcept C135763542 @default.
• W2003626688 hasConcept C141231307 @default.

• next