Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003639153> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2003639153 endingPage "62" @default.
- W2003639153 startingPage "53" @default.
- W2003639153 abstract "Purpose: The purpose of this article is to describe new methodology, antimicrobial efficacy endpoint methodology to determine compatibility of contact lens solutions, lens cases and hydrogel lenses for disinfection (AEEMC), to evaluate the effect of a contact lens and a lens case on disinfection efficacy, and to present the ring test used to justify the use of the method in multiple laboratories. Materials and Methods: A prototype solution containing chlorhexidine as the disinfecting agent and four representative lens types (group I and IV hydrogels and two silicone hydrogels) were used in these ring tests. Five laboratories participated in the chemical and microbiologic analyses. The residual chlorhexidine in lens cases containing the contact lenses was determined using high-performance liquid chromatography; uptake by the lenses was then determined by extrapolation. For the microbiologic part of the study, a contact lens was placed in the well of the lens case, inoculated at 105 to 106 cfu (colony forming units) per lens with microorganisms in 10% organic soil. The microorganisms, Pseudomonas aeruginosa, Serratia marcescens, Staphylococcus aureus, Candida albicans, and Fusarium solani, were prepared as in International Organization for Standardization (ISO) 14729. After a 3- to 10-min exposure time, the prototype solution was dispensed into each well. Aliquots of the inoculated solutions were removed at 4 and 24 hrs and 7 and 30 days and cultured in neutralizing media for determination of survivors; lenses were also cultured for survivors. Results: Chemical uptake data confirmed the differences observed in kill of the challenge organisms according to lens type. It was observed that the culturing of the solution provided adequate data to show the effect of a lens on disinfection efficacy of a lens care product. The findings of the ring test indicated that the separate culturing of the contact lenses is not necessary for routine assessment. Conclusions: The methodology in the November 12, 2008, draft standard (AEEMC), meets the stated objective of demonstrating the effect of a contact lens on the disinfection efficacy of a simulated lens care product. This method, used in combination with the methodology in ISO 14729, should provide for a more robust evaluation of applicable contact lens care disinfecting products." @default.
- W2003639153 created "2016-06-24" @default.
- W2003639153 creator A5033942912 @default.
- W2003639153 creator A5044660595 @default.
- W2003639153 creator A5048556389 @default.
- W2003639153 creator A5076504896 @default.
- W2003639153 creator A5077822041 @default.
- W2003639153 date "2012-01-01" @default.
- W2003639153 modified "2023-09-27" @default.
- W2003639153 title "A New Method for Evaluation of Compatibility of Contact Lenses and Lens Cases With Contact Lens Disinfecting Solutions" @default.
- W2003639153 cites W1976448260 @default.
- W2003639153 cites W1977502680 @default.
- W2003639153 cites W2007511867 @default.
- W2003639153 cites W2116582646 @default.
- W2003639153 cites W2149336702 @default.
- W2003639153 doi "https://doi.org/10.1097/icl.0b013e3182411fba" @default.
- W2003639153 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22178791" @default.
- W2003639153 hasPublicationYear "2012" @default.
- W2003639153 type Work @default.
- W2003639153 sameAs 2003639153 @default.
- W2003639153 citedByCount "8" @default.
- W2003639153 countsByYear W20036391532012 @default.
- W2003639153 countsByYear W20036391532013 @default.
- W2003639153 countsByYear W20036391532015 @default.
- W2003639153 countsByYear W20036391532018 @default.
- W2003639153 countsByYear W20036391532021 @default.
- W2003639153 crossrefType "journal-article" @default.
- W2003639153 hasAuthorship W2003639153A5033942912 @default.
- W2003639153 hasAuthorship W2003639153A5044660595 @default.
- W2003639153 hasAuthorship W2003639153A5048556389 @default.
- W2003639153 hasAuthorship W2003639153A5076504896 @default.
- W2003639153 hasAuthorship W2003639153A5077822041 @default.
- W2003639153 hasConcept C108586683 @default.
- W2003639153 hasConcept C118487528 @default.
- W2003639153 hasConcept C120665830 @default.
- W2003639153 hasConcept C121332964 @default.
- W2003639153 hasConcept C136229726 @default.
- W2003639153 hasConcept C15336307 @default.
- W2003639153 hasConcept C185592680 @default.
- W2003639153 hasConcept C188027245 @default.
- W2003639153 hasConcept C192562407 @default.
- W2003639153 hasConcept C199343813 @default.
- W2003639153 hasConcept C2777084678 @default.
- W2003639153 hasConcept C2780917455 @default.
- W2003639153 hasConcept C2986805488 @default.
- W2003639153 hasConcept C43617362 @default.
- W2003639153 hasConcept C4937899 @default.
- W2003639153 hasConcept C71924100 @default.
- W2003639153 hasConcept C86803240 @default.
- W2003639153 hasConcept C89423630 @default.
- W2003639153 hasConceptScore W2003639153C108586683 @default.
- W2003639153 hasConceptScore W2003639153C118487528 @default.
- W2003639153 hasConceptScore W2003639153C120665830 @default.
- W2003639153 hasConceptScore W2003639153C121332964 @default.
- W2003639153 hasConceptScore W2003639153C136229726 @default.
- W2003639153 hasConceptScore W2003639153C15336307 @default.
- W2003639153 hasConceptScore W2003639153C185592680 @default.
- W2003639153 hasConceptScore W2003639153C188027245 @default.
- W2003639153 hasConceptScore W2003639153C192562407 @default.
- W2003639153 hasConceptScore W2003639153C199343813 @default.
- W2003639153 hasConceptScore W2003639153C2777084678 @default.
- W2003639153 hasConceptScore W2003639153C2780917455 @default.
- W2003639153 hasConceptScore W2003639153C2986805488 @default.
- W2003639153 hasConceptScore W2003639153C43617362 @default.
- W2003639153 hasConceptScore W2003639153C4937899 @default.
- W2003639153 hasConceptScore W2003639153C71924100 @default.
- W2003639153 hasConceptScore W2003639153C86803240 @default.
- W2003639153 hasConceptScore W2003639153C89423630 @default.
- W2003639153 hasIssue "1" @default.
- W2003639153 hasLocation W20036391531 @default.
- W2003639153 hasLocation W20036391532 @default.
- W2003639153 hasOpenAccess W2003639153 @default.
- W2003639153 hasPrimaryLocation W20036391531 @default.
- W2003639153 hasRelatedWork W1982347671 @default.
- W2003639153 hasRelatedWork W1987805284 @default.
- W2003639153 hasRelatedWork W2027843124 @default.
- W2003639153 hasRelatedWork W2156160379 @default.
- W2003639153 hasRelatedWork W2322960368 @default.
- W2003639153 hasRelatedWork W2755435813 @default.
- W2003639153 hasRelatedWork W2947654540 @default.
- W2003639153 hasRelatedWork W2958656260 @default.
- W2003639153 hasRelatedWork W3104356446 @default.
- W2003639153 hasRelatedWork W4380904795 @default.
- W2003639153 hasVolume "38" @default.
- W2003639153 isParatext "false" @default.
- W2003639153 isRetracted "false" @default.
- W2003639153 magId "2003639153" @default.
- W2003639153 workType "article" @default.