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• W2003667054 abstract "The significance of epidermal growth factor receptor (EGFR) expression in advanced cutaneous squamous cell carcinoma (SCC) of the head and neck remains poorly understood.We performed a retrospective review of patients with advanced-stage (stage III or stage IV) cutaneous SCC of the head and neck (n = 56).The majority of patients (91%) had stage III disease, with 54% having regional metastasis and 9% with distant metastasis. Two-year survival was 64% and the 5-year survival was 56%. EGFR was found to be overexpressed in 56% of primary tumors and 58% of regional metastatic disease. Overall survival did not correlate with EGFR (p = .47) expression in primary lesions, nor was it associated with an increase in regional (p = .74) or distant metastasis (p = .56). Furthermore, there was no correlation between clinicopathologic characteristics and EGFR expressionThese data do not suggest upregulation of EGFR is associated with poor survival or aggressive disease." @default.
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• W2003667054 date "2011-07-07" @default.
• W2003667054 modified "2023-09-24" @default.
• W2003667054 title "EGFR expression in advanced head and neck cutaneous squamous cell carcinoma" @default.
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• W2003667054 doi "https://doi.org/10.1002/hed.21802" @default.
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