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- W2003683523 abstract "Changes in intracellular Ca2+ concentration were monitored in cultured cortical astrocytes challenged with ryanodine and ATP. Ryanodine elicited a modest, in comparison to ATP, increase in cytosolic Ca2+ concentration in approximately 60% of the cell fields examined. This effect was evident and, in fact, was augmented when incubations were performed in Ca2+ concentration were dose dependent, desensitised rapidly, and could not be mimicked by caffeine. Exposure to ryanodine was without effect on eicosanoid release from these cells nor did it influence Ca2+ mobilisation and eicosanoid release in response to ATP. In contrast, caffeine attenuated part of the ATP-evoked increase in intracellular Ca2+ concentration in the majority of cells tested and abolished its effect on eicosanoid release." @default.
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- W2003683523 title "Ryanodine-induced intracellular calcium mobilisation in cultured astrocytes" @default.
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- W2003683523 doi "https://doi.org/10.1002/glia.440120206" @default.
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