Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003687462> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W2003687462 endingPage "356" @default.
- W2003687462 startingPage "345" @default.
- W2003687462 abstract "Lobulated fibers have been observed in biopsies of 13 patients with various neuromuscular disorders including limb-girdle muscular dystrophy (3), distal myopathy (2), scapuloperoneal muscular dystrophy (2), congenital myopathy, Kugelberg-Welander syndrome, hypothyroidism, steroid myopathy, osteomalacia and systemic lupus erythematosus (on steroids). In all cases there were fibers characterised by small subsarcolemmal triangular aggregates or more diffuse collections extending into the interior of the muscle fiber. These were strongly reactive with oxidative enzymes, acid phosphatase, periodic acid-Schiff (PAS), Verhoeff-van Gieson (VVG) and also stained red with the Gomori trichrome technique. In 5 cases core-like fibers were also seen. Morphometric analysis of the NADH-tetrazolium reductase (NADH-TR) preparations in 11 cases showed atrophy of the lobulated fibers. Ultrastructural studies of lobulated fibers disclosed large peripheral mitochondrial aggregates and focal areas with Z-line streaming and disrupted myofibrils. We consider this structural change of the muscle fiber as a reflection of muscle cell disruption and suggest that they may progress from lobulated fibers to more atrophic core-like fibers." @default.
- W2003687462 created "2016-06-24" @default.
- W2003687462 creator A5024645490 @default.
- W2003687462 creator A5029621491 @default.
- W2003687462 creator A5068487089 @default.
- W2003687462 date "1985-07-01" @default.
- W2003687462 modified "2023-09-23" @default.
- W2003687462 title "Lobulated fibers in neuromuscular diseases" @default.
- W2003687462 cites W2038595235 @default.
- W2003687462 cites W2080378715 @default.
- W2003687462 cites W2115702745 @default.
- W2003687462 cites W2237199369 @default.
- W2003687462 cites W4232928223 @default.
- W2003687462 doi "https://doi.org/10.1016/0022-510x(85)90145-5" @default.
- W2003687462 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3162002" @default.
- W2003687462 hasPublicationYear "1985" @default.
- W2003687462 type Work @default.
- W2003687462 sameAs 2003687462 @default.
- W2003687462 citedByCount "28" @default.
- W2003687462 countsByYear W20036874622012 @default.
- W2003687462 countsByYear W20036874622013 @default.
- W2003687462 countsByYear W20036874622015 @default.
- W2003687462 countsByYear W20036874622018 @default.
- W2003687462 crossrefType "journal-article" @default.
- W2003687462 hasAuthorship W2003687462A5024645490 @default.
- W2003687462 hasAuthorship W2003687462A5029621491 @default.
- W2003687462 hasAuthorship W2003687462A5068487089 @default.
- W2003687462 hasConcept C105702510 @default.
- W2003687462 hasConcept C126322002 @default.
- W2003687462 hasConcept C134018914 @default.
- W2003687462 hasConcept C142724271 @default.
- W2003687462 hasConcept C163031210 @default.
- W2003687462 hasConcept C185592680 @default.
- W2003687462 hasConcept C2777300911 @default.
- W2003687462 hasConcept C2779030066 @default.
- W2003687462 hasConcept C2781172350 @default.
- W2003687462 hasConcept C71924100 @default.
- W2003687462 hasConcept C7301908 @default.
- W2003687462 hasConcept C74864618 @default.
- W2003687462 hasConcept C86803240 @default.
- W2003687462 hasConceptScore W2003687462C105702510 @default.
- W2003687462 hasConceptScore W2003687462C126322002 @default.
- W2003687462 hasConceptScore W2003687462C134018914 @default.
- W2003687462 hasConceptScore W2003687462C142724271 @default.
- W2003687462 hasConceptScore W2003687462C163031210 @default.
- W2003687462 hasConceptScore W2003687462C185592680 @default.
- W2003687462 hasConceptScore W2003687462C2777300911 @default.
- W2003687462 hasConceptScore W2003687462C2779030066 @default.
- W2003687462 hasConceptScore W2003687462C2781172350 @default.
- W2003687462 hasConceptScore W2003687462C71924100 @default.
- W2003687462 hasConceptScore W2003687462C7301908 @default.
- W2003687462 hasConceptScore W2003687462C74864618 @default.
- W2003687462 hasConceptScore W2003687462C86803240 @default.
- W2003687462 hasIssue "3" @default.
- W2003687462 hasLocation W20036874621 @default.
- W2003687462 hasLocation W20036874622 @default.
- W2003687462 hasOpenAccess W2003687462 @default.
- W2003687462 hasPrimaryLocation W20036874621 @default.
- W2003687462 hasRelatedWork W143271202 @default.
- W2003687462 hasRelatedWork W1517343105 @default.
- W2003687462 hasRelatedWork W1978132373 @default.
- W2003687462 hasRelatedWork W198204066 @default.
- W2003687462 hasRelatedWork W2082916096 @default.
- W2003687462 hasRelatedWork W2093887910 @default.
- W2003687462 hasRelatedWork W2105548788 @default.
- W2003687462 hasRelatedWork W2330685837 @default.
- W2003687462 hasRelatedWork W2396118028 @default.
- W2003687462 hasRelatedWork W4239689251 @default.
- W2003687462 hasVolume "69" @default.
- W2003687462 isParatext "false" @default.
- W2003687462 isRetracted "false" @default.
- W2003687462 magId "2003687462" @default.
- W2003687462 workType "article" @default.