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- W2003706107 abstract "We would like to draw attention to arthritis and arthralgia as monosymptomatic forms of CD. There are few reports on this association in the literature and in paediatric patients the coexistens of CD and arthritis has not been documented. After finding four index cases we have screened children with joint symptoms for antireticulin antibodies (ARA). During the years 1982-86 ARA were tested whenever an antinuclear antibody test was requested. Small bowel biopsy was performed in 10 of 11 children positive for ARA. All the 7 children 4 to 16 years of age positive for IgA-ARA (titres 1:100 to 1:4000) had small, flat intestinal mucosa (SVA). Three of them had also IgG-ARA detectable in their serum. Three children with IgG-ARA only were normal on biopsy. During gluten-free diet disappearance of ARA in the children with SVA correlated well with mucosal recovery on control biopsy. We conclude that IgA-ARA is suitable for screening CD among children with arthritis. The role of IgG-class ARA in children with joint complaints and normal intestinal mucosa is unknown. Arthritis and arthralgia should be included in the list of monosymptomatic forms of CD." @default.
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- W2003706107 date "1987-07-01" @default.
- W2003706107 modified "2023-10-16" @default.
- W2003706107 title "34. ARTHRITIS IN CHILDHOOD COELIAC DISEASE (CD)" @default.
- W2003706107 doi "https://doi.org/10.1203/00006450-198707000-00055" @default.
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