FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003708944> ?p ?o ?g. }

• W2003708944 endingPage "272" @default.
• W2003708944 startingPage "263" @default.
• W2003708944 abstract "Isolated mammary nuclei were incubated in the presence of HgCTP and the neosynthesized RNA was isolated with a SH-Sepharose column. The concentration of beta-casein mRNA and 28-S ribosomal RNA in the neosynthesized RNA fractions was evaluated using [3H]DNA probes complementary to beta-casein mRNA and 28-S rRNA respectively. In the unstimulated pseudopregnant rabbit, the transcription of both genes was easily detectable. Injections of prolactin progressively enhanced the transcription rate of both genes and preferentially the beta-casein gene. A comparison between the transcription rates and the accumulation of the corresponding gene products in the cell revealed that there is a good correlation between these two parameters for the 28-S rRNA gene. By contrast, the acceleration of beta-casein gene transcription by prolactin is unable to account for the simultaneous accumulation of beta-casein mRNA, indicating that prolactin is a potent stabilizer of casein mRNA. Injections of CB154 into lactating rabbits (a drug which suppresses the secretion of prolactin by hypophysis), induced a rapid drop of beta-casein mRNA concentration and a slow decline of beta-casein gene transcription. Simultaneously the drug was responsible for a marked and rapid decrease of 28-S rRNA gene transcription, while the concentration of the rRNA remained elevated. During weaning the transcription of the beta-casein gene and, to a lower degree, the transcripton of the 28-S rRNA gene proceeded more slowly and this phenomenon was accompanied by a progressive decline of the RNA concentrations." @default.
• W2003708944 created "2016-06-24" @default.
• W2003708944 creator A5029262018 @default.
• W2003708944 creator A5039010213 @default.
• W2003708944 date "1980-09-01" @default.
• W2003708944 modified "2023-09-30" @default.
• W2003708944 title "Role of Prolactin in the Transcription of beta-Casein and 28-S Ribosomal Genes in the Rabbit Mammary Gland" @default.
• W2003708944 cites W1496960451 @default.
• W2003708944 cites W1564149955 @default.
• W2003708944 cites W1598530978 @default.
• W2003708944 cites W1603065538 @default.
• W2003708944 cites W1635738393 @default.
• W2003708944 cites W1906197854 @default.
• W2003708944 cites W1967142578 @default.
• W2003708944 cites W1967747448 @default.
• W2003708944 cites W1970754615 @default.
• W2003708944 cites W1976658927 @default.
• W2003708944 cites W1980325766 @default.
• W2003708944 cites W1981173096 @default.
• W2003708944 cites W1983520193 @default.
• W2003708944 cites W1986810471 @default.
• W2003708944 cites W1989429216 @default.
• W2003708944 cites W1989497552 @default.
• W2003708944 cites W1996100048 @default.
• W2003708944 cites W1996263306 @default.
• W2003708944 cites W1998750490 @default.
• W2003708944 cites W2000941741 @default.
• W2003708944 cites W2002055583 @default.
• W2003708944 cites W2006506558 @default.
• W2003708944 cites W2006633837 @default.
• W2003708944 cites W2007205949 @default.
• W2003708944 cites W2009691249 @default.
• W2003708944 cites W2014940983 @default.
• W2003708944 cites W2015151228 @default.
• W2003708944 cites W2016203765 @default.
• W2003708944 cites W2026833305 @default.
• W2003708944 cites W2030540572 @default.
• W2003708944 cites W2032454324 @default.
• W2003708944 cites W2036917468 @default.
• W2003708944 cites W2036941847 @default.
• W2003708944 cites W2044525314 @default.
• W2003708944 cites W2047419115 @default.
• W2003708944 cites W2056680966 @default.
• W2003708944 cites W2056948458 @default.
• W2003708944 cites W2057752705 @default.
• W2003708944 cites W2057939756 @default.
• W2003708944 cites W2058274163 @default.
• W2003708944 cites W2060894279 @default.
• W2003708944 cites W2061032145 @default.
• W2003708944 cites W2066462610 @default.
• W2003708944 cites W2072633380 @default.
• W2003708944 cites W2076510744 @default.
• W2003708944 cites W2076741253 @default.
• W2003708944 cites W2077735596 @default.
• W2003708944 cites W2078045347 @default.
• W2003708944 cites W2080759619 @default.
• W2003708944 cites W2081830584 @default.
• W2003708944 cites W2082831376 @default.
• W2003708944 cites W2083138958 @default.
• W2003708944 cites W2089031185 @default.
• W2003708944 cites W2103667953 @default.
• W2003708944 cites W2142889112 @default.
• W2003708944 cites W2150056153 @default.
• W2003708944 cites W2151211512 @default.
• W2003708944 cites W2326359222 @default.
• W2003708944 cites W62080596 @default.
• W2003708944 doi "https://doi.org/10.1111/j.1432-1033.1980.tb04864.x" @default.
• W2003708944 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7192213" @default.
• W2003708944 hasPublicationYear "1980" @default.
• W2003708944 type Work @default.
• W2003708944 sameAs 2003708944 @default.
• W2003708944 citedByCount "34" @default.
• W2003708944 countsByYear W20037089442016 @default.
• W2003708944 countsByYear W20037089442019 @default.
• W2003708944 crossrefType "journal-article" @default.
• W2003708944 hasAuthorship W2003708944A5029262018 @default.
• W2003708944 hasAuthorship W2003708944A5039010213 @default.
• W2003708944 hasBestOaLocation W20037089441 @default.
• W2003708944 hasConcept C104317684 @default.
• W2003708944 hasConcept C105580179 @default.
• W2003708944 hasConcept C134018914 @default.
• W2003708944 hasConcept C138885662 @default.
• W2003708944 hasConcept C150194340 @default.
• W2003708944 hasConcept C153911025 @default.
• W2003708944 hasConcept C179926584 @default.
• W2003708944 hasConcept C2776142715 @default.
• W2003708944 hasConcept C2779064019 @default.
• W2003708944 hasConcept C41895202 @default.
• W2003708944 hasConcept C55493867 @default.
• W2003708944 hasConcept C67705224 @default.
• W2003708944 hasConcept C67905577 @default.
• W2003708944 hasConcept C71315377 @default.
• W2003708944 hasConcept C86803240 @default.
• W2003708944 hasConceptScore W2003708944C104317684 @default.
• W2003708944 hasConceptScore W2003708944C105580179 @default.
• W2003708944 hasConceptScore W2003708944C134018914 @default.
• W2003708944 hasConceptScore W2003708944C138885662 @default.
• W2003708944 hasConceptScore W2003708944C150194340 @default.

• next