FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003715208> ?p ?o ?g. }

• W2003715208 endingPage "653" @default.
• W2003715208 startingPage "647" @default.
• W2003715208 abstract "Purpose We assessed clinical outcome and long-term tumor control after fractionated stereotactic radiotherapy (FSRT) for unilateral schwannoma. Methods and Materials Between 1995 and 2007, 496 patients were treated with fractionated stereotactic radiotherapy at Johns Hopkins Hospital (Baltimore, MD); 385 patients had radiologic follow-up that met the inclusion criteria. The primary endpoint was treatment failure. Secondary endpoints were radiologic progression and clinical outcome. Logistic regression analysis assessed the association of age, race, tumor side, sex, and pretreatment symptoms. Results In 11 patients (3%) treatment failed, and they required salvage (microsurgical) treatment. Radiologic progression was observed in 116 patients (30.0%), including 35 patients (9%) in whom the treatment volume more than doubled during the follow-up period, although none required surgical resection. Tumors with baseline volumes of less than 1 cm3 were 18.02 times more likely to progress than those with tumor volumes of 1 cm3 or greater (odds ratio, 18.02; 95% confidence interval, 4.25–76.32). Treatment-induced neurologic morbidity included 8 patients (1.6%) with new facial weakness, 12 patients (2.8%) with new trigeminal paresthesias, 4 patients (0.9%) with hydrocephalus (1 communicating and 3 obstructive), and 2 patients (0.5%) with possibly radiation-induced neoplasia. Conclusions Although the rate of treatment failure is low (3%), careful follow-up shows that radiologic progression occurs frequently. When reporting outcome, the “no salvage surgery needed” and “no additional treatment needed” criteria for treatment success need to be complemented by the radiologic data. We assessed clinical outcome and long-term tumor control after fractionated stereotactic radiotherapy (FSRT) for unilateral schwannoma. Between 1995 and 2007, 496 patients were treated with fractionated stereotactic radiotherapy at Johns Hopkins Hospital (Baltimore, MD); 385 patients had radiologic follow-up that met the inclusion criteria. The primary endpoint was treatment failure. Secondary endpoints were radiologic progression and clinical outcome. Logistic regression analysis assessed the association of age, race, tumor side, sex, and pretreatment symptoms. In 11 patients (3%) treatment failed, and they required salvage (microsurgical) treatment. Radiologic progression was observed in 116 patients (30.0%), including 35 patients (9%) in whom the treatment volume more than doubled during the follow-up period, although none required surgical resection. Tumors with baseline volumes of less than 1 cm3 were 18.02 times more likely to progress than those with tumor volumes of 1 cm3 or greater (odds ratio, 18.02; 95% confidence interval, 4.25–76.32). Treatment-induced neurologic morbidity included 8 patients (1.6%) with new facial weakness, 12 patients (2.8%) with new trigeminal paresthesias, 4 patients (0.9%) with hydrocephalus (1 communicating and 3 obstructive), and 2 patients (0.5%) with possibly radiation-induced neoplasia. Although the rate of treatment failure is low (3%), careful follow-up shows that radiologic progression occurs frequently. When reporting outcome, the “no salvage surgery needed” and “no additional treatment needed” criteria for treatment success need to be complemented by the radiologic data." @default.
• W2003715208 created "2016-06-24" @default.
• W2003715208 creator A5003663698 @default.
• W2003715208 creator A5010803921 @default.
• W2003715208 creator A5020333115 @default.
• W2003715208 creator A5021607259 @default.
• W2003715208 creator A5026013783 @default.
• W2003715208 creator A5033231728 @default.
• W2003715208 creator A5072491825 @default.
• W2003715208 creator A5074625426 @default.
• W2003715208 creator A5075186834 @default.
• W2003715208 creator A5075546201 @default.
• W2003715208 creator A5085502405 @default.
• W2003715208 creator A5088344413 @default.
• W2003715208 date "2011-11-01" @default.
• W2003715208 modified "2023-10-12" @default.
• W2003715208 title "Long-Term Outcomes of Vestibular Schwannomas Treated With Fractionated Stereotactic Radiotherapy: An Institutional Experience" @default.
• W2003715208 cites W1482296083 @default.
• W2003715208 cites W1963689145 @default.
• W2003715208 cites W1977752341 @default.
• W2003715208 cites W1986315283 @default.
• W2003715208 cites W2005433545 @default.
• W2003715208 cites W2011680861 @default.
• W2003715208 cites W2027974765 @default.
• W2003715208 cites W2041569058 @default.
• W2003715208 cites W2046643663 @default.
• W2003715208 cites W2048977508 @default.
• W2003715208 cites W2059612995 @default.
• W2003715208 cites W2059635690 @default.
• W2003715208 cites W2071436507 @default.
• W2003715208 cites W2087788207 @default.
• W2003715208 cites W2088441548 @default.
• W2003715208 cites W2090407171 @default.
• W2003715208 cites W2097830687 @default.
• W2003715208 cites W2104910075 @default.
• W2003715208 cites W2130317227 @default.
• W2003715208 cites W2143622647 @default.
• W2003715208 cites W2153662176 @default.
• W2003715208 cites W2158837088 @default.
• W2003715208 cites W2159309879 @default.
• W2003715208 cites W2334769366 @default.
• W2003715208 cites W4247302141 @default.
• W2003715208 cites W4252793238 @default.
• W2003715208 doi "https://doi.org/10.1016/j.ijrobp.2010.06.006" @default.
• W2003715208 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4042401" @default.
• W2003715208 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20884130" @default.
• W2003715208 hasPublicationYear "2011" @default.
• W2003715208 type Work @default.
• W2003715208 sameAs 2003715208 @default.
• W2003715208 citedByCount "49" @default.
• W2003715208 countsByYear W20037152082012 @default.
• W2003715208 countsByYear W20037152082013 @default.
• W2003715208 countsByYear W20037152082014 @default.
• W2003715208 countsByYear W20037152082015 @default.
• W2003715208 countsByYear W20037152082016 @default.
• W2003715208 countsByYear W20037152082017 @default.
• W2003715208 countsByYear W20037152082018 @default.
• W2003715208 countsByYear W20037152082019 @default.
• W2003715208 countsByYear W20037152082021 @default.
• W2003715208 countsByYear W20037152082022 @default.
• W2003715208 countsByYear W20037152082023 @default.
• W2003715208 crossrefType "journal-article" @default.
• W2003715208 hasAuthorship W2003715208A5003663698 @default.
• W2003715208 hasAuthorship W2003715208A5010803921 @default.
• W2003715208 hasAuthorship W2003715208A5020333115 @default.
• W2003715208 hasAuthorship W2003715208A5021607259 @default.
• W2003715208 hasAuthorship W2003715208A5026013783 @default.
• W2003715208 hasAuthorship W2003715208A5033231728 @default.
• W2003715208 hasAuthorship W2003715208A5072491825 @default.
• W2003715208 hasAuthorship W2003715208A5074625426 @default.
• W2003715208 hasAuthorship W2003715208A5075186834 @default.
• W2003715208 hasAuthorship W2003715208A5075546201 @default.
• W2003715208 hasAuthorship W2003715208A5085502405 @default.
• W2003715208 hasAuthorship W2003715208A5088344413 @default.
• W2003715208 hasBestOaLocation W20037152082 @default.
• W2003715208 hasConcept C126322002 @default.
• W2003715208 hasConcept C126838900 @default.
• W2003715208 hasConcept C141071460 @default.
• W2003715208 hasConcept C156957248 @default.
• W2003715208 hasConcept C168563851 @default.
• W2003715208 hasConcept C203092338 @default.
• W2003715208 hasConcept C2776694085 @default.
• W2003715208 hasConcept C2780387249 @default.
• W2003715208 hasConcept C2780775027 @default.
• W2003715208 hasConcept C2781447767 @default.
• W2003715208 hasConcept C2992393070 @default.
• W2003715208 hasConcept C44249647 @default.
• W2003715208 hasConcept C509974204 @default.
• W2003715208 hasConcept C71924100 @default.
• W2003715208 hasConceptScore W2003715208C126322002 @default.
• W2003715208 hasConceptScore W2003715208C126838900 @default.
• W2003715208 hasConceptScore W2003715208C141071460 @default.
• W2003715208 hasConceptScore W2003715208C156957248 @default.
• W2003715208 hasConceptScore W2003715208C168563851 @default.
• W2003715208 hasConceptScore W2003715208C203092338 @default.
• W2003715208 hasConceptScore W2003715208C2776694085 @default.
• W2003715208 hasConceptScore W2003715208C2780387249 @default.
• W2003715208 hasConceptScore W2003715208C2780775027 @default.

• next