Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003757291> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W2003757291 abstract "The survival of UV-irradiated Simian virus 40 (SV40) in CV-1P African green monkey kidney cells treated with (+/-)7 beta, 8 alpha-dihydroxy-9 alpha, 10 alpha epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene (BP-diol epoxide I) was studied. Enhanced survival of UV damaged SV40 was detected when CV-1P cells were treated with dose levels of BP-diol epoxide I corresponding to the exponential portion (0.33-1.11 microM) of a CV-1P cell survival curve. Dose levels of BP-diol epoxide I corresponding to the shoulder region (less than or equal to 0.16 microM) of a CV-1P survival curve did not induce viral reactivation. The shoulder region concentrations of BP-diol epoxide I selectively inhibited DNA initiation while the concentrations on the exponential portion of the curve preferentially inhibited DNA elongation. It was shown in a time course of enhanced viral survival at 0.66 microM BP-diol epoxide I that the reactivation response was fully induced by 24 h. In conclusion, the viral reactivation response was associated with concentrations of BP-diol epoxide I which induced lethal damage and preferentially inhibited DNA elongation." @default.
- W2003757291 created "2016-06-24" @default.
- W2003757291 creator A5055376182 @default.
- W2003757291 creator A5068265645 @default.
- W2003757291 creator A5075326202 @default.
- W2003757291 date "1986-01-01" @default.
- W2003757291 modified "2023-10-17" @default.
- W2003757291 title "Benzo[a]pyrene diol epoxide induces viral reactivation at concentrations that block dna elongation in mammalian cells" @default.
- W2003757291 cites W1552078262 @default.
- W2003757291 cites W1976917904 @default.
- W2003757291 cites W1979888163 @default.
- W2003757291 cites W1980011976 @default.
- W2003757291 cites W1981218329 @default.
- W2003757291 cites W1996127066 @default.
- W2003757291 cites W2013341053 @default.
- W2003757291 cites W2036302298 @default.
- W2003757291 cites W2053831943 @default.
- W2003757291 cites W2067893419 @default.
- W2003757291 cites W2077325314 @default.
- W2003757291 cites W2088136616 @default.
- W2003757291 cites W2118128934 @default.
- W2003757291 cites W2152715413 @default.
- W2003757291 cites W2410555917 @default.
- W2003757291 cites W2797953954 @default.
- W2003757291 cites W951790091 @default.
- W2003757291 doi "https://doi.org/10.1016/s0009-2797(86)80107-7" @default.
- W2003757291 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3017584" @default.
- W2003757291 hasPublicationYear "1986" @default.
- W2003757291 type Work @default.
- W2003757291 sameAs 2003757291 @default.
- W2003757291 citedByCount "3" @default.
- W2003757291 crossrefType "journal-article" @default.
- W2003757291 hasAuthorship W2003757291A5055376182 @default.
- W2003757291 hasAuthorship W2003757291A5068265645 @default.
- W2003757291 hasAuthorship W2003757291A5075326202 @default.
- W2003757291 hasConcept C112950240 @default.
- W2003757291 hasConcept C153911025 @default.
- W2003757291 hasConcept C161790260 @default.
- W2003757291 hasConcept C178790620 @default.
- W2003757291 hasConcept C185592680 @default.
- W2003757291 hasConcept C191897082 @default.
- W2003757291 hasConcept C192562407 @default.
- W2003757291 hasConcept C2776920199 @default.
- W2003757291 hasConcept C2777538855 @default.
- W2003757291 hasConcept C2778951431 @default.
- W2003757291 hasConcept C2779515768 @default.
- W2003757291 hasConcept C33947775 @default.
- W2003757291 hasConcept C552990157 @default.
- W2003757291 hasConcept C55493867 @default.
- W2003757291 hasConcept C71240020 @default.
- W2003757291 hasConcept C86803240 @default.
- W2003757291 hasConceptScore W2003757291C112950240 @default.
- W2003757291 hasConceptScore W2003757291C153911025 @default.
- W2003757291 hasConceptScore W2003757291C161790260 @default.
- W2003757291 hasConceptScore W2003757291C178790620 @default.
- W2003757291 hasConceptScore W2003757291C185592680 @default.
- W2003757291 hasConceptScore W2003757291C191897082 @default.
- W2003757291 hasConceptScore W2003757291C192562407 @default.
- W2003757291 hasConceptScore W2003757291C2776920199 @default.
- W2003757291 hasConceptScore W2003757291C2777538855 @default.
- W2003757291 hasConceptScore W2003757291C2778951431 @default.
- W2003757291 hasConceptScore W2003757291C2779515768 @default.
- W2003757291 hasConceptScore W2003757291C33947775 @default.
- W2003757291 hasConceptScore W2003757291C552990157 @default.
- W2003757291 hasConceptScore W2003757291C55493867 @default.
- W2003757291 hasConceptScore W2003757291C71240020 @default.
- W2003757291 hasConceptScore W2003757291C86803240 @default.
- W2003757291 hasLocation W20037572911 @default.
- W2003757291 hasLocation W20037572912 @default.
- W2003757291 hasOpenAccess W2003757291 @default.
- W2003757291 hasPrimaryLocation W20037572911 @default.
- W2003757291 hasRelatedWork W1992829789 @default.
- W2003757291 hasRelatedWork W1998268094 @default.
- W2003757291 hasRelatedWork W2000618108 @default.
- W2003757291 hasRelatedWork W2019605110 @default.
- W2003757291 hasRelatedWork W2025055646 @default.
- W2003757291 hasRelatedWork W2055645726 @default.
- W2003757291 hasRelatedWork W206888205 @default.
- W2003757291 hasRelatedWork W2070572646 @default.
- W2003757291 hasRelatedWork W2950285661 @default.
- W2003757291 hasRelatedWork W2950941227 @default.
- W2003757291 isParatext "false" @default.
- W2003757291 isRetracted "false" @default.
- W2003757291 magId "2003757291" @default.
- W2003757291 workType "article" @default.