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- W2003758387 abstract "We studied the postnatal development of the corticopontine tract in mice by the injection of the axon tracer DiI into the visual cortex. In the postnatal day (P) 0.5 mouse, labeled pyramidal tract fibers pass through the internal capsule and cerebral peduncle, grow over the basilar pontine gray, and enter into the medullary pyramid (in this study, P0 refers to the first 24 hours after birth). Small collateral branches arise from these pyramidal tract fibers on P0.5-1.0, and elongate quickly into the basilar pontine gray around P2-4. These collateral branches give off many secondary branches on P4 and form the bright terminal zone in the rostral portion of the lateral basilar pontine gray on P9. In the P16 mouse, this terminal zone is more restricted, suggesting, on the basis of the anterograde DiI labeling technique, that the visual corticopontine projection matures by P16. DiI-labeled pyramidal tract fibers distal to the branching point of the pontine collaterals are found during the postnatal two weeks, but disappear by the later stages. We conclude that the visual corticopontine tract develops as collateral branches of the transient pyramidal tract fibers arising from the visual cortex of the mouse, as just described in the rat (O'Leary and Terashima, Neuron 1:901-910, 1988)." @default.
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- W2003758387 date "1991-01-01" @default.
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- W2003758387 title "Postnatal Development of the Pontine Projections from the Visual Cortex of the Mouse" @default.
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- W2003758387 doi "https://doi.org/10.2535/ofaj1936.67.6_479" @default.
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