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- W2003782647 abstract "A novel series of 6-benzyl substituted 4-aminocarbonyl-1,4-diazepane-2,5-diones were explored as human chymase inhibitors using structure-based drug design according to the X-ray cocrystal structure of chymase and compound 1. The optimization focused on the prime site led to the attainment of compounds that showed potent inhibitory activity, and among them, 18R shows a novel interaction mode." @default.
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- W2003782647 date "2013-07-01" @default.
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- W2003782647 title "Discovery of novel series of 6-benzyl substituted 4-aminocarbonyl-1,4-diazepane-2,5-diones as human chymase inhibitors using structure-based drug design" @default.
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- W2003782647 doi "https://doi.org/10.1016/j.bmc.2013.04.079" @default.
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