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• W2003783885 abstract "We compared the effect of alfentanil 10 µg.kg −1 and esmolol 1.5 mg.kg −1 on the cardiovascular responses to laryngoscopy and double‐lumen endobronchial intubation in two groups of 20 ASA 2–3 patients undergoing pulmonary surgery, in a randomised double‐blind study. Arterial pressure and heart rate decreased after induction of anaesthesia and increased after intubation in both groups (p < 0.05) but remained at or below baseline values, and changes were comparable in both groups. Plasma catecholamine concentrations decreased after induction of anaesthesia in both groups (p < 0.05). Epinephrine concentrations increased in the esmolol group after intubation (p < 0.05) but remained below baseline in the alfentanil group (p < 0.05). Norepinephrine concentrations increased significantly in both groups after intubation but were higher in the esmolol group (p < 0.05). Although both esmolol 1.5 mg.kg −1 and alfentanil 10 µg.kg −1 similarly attenuated the arterial pressure and heart rate response to endobronchial intubation, plasma catecholamine concentrations increased in the esmolol group to values greater than previously reported after tracheal intubation." @default.
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• W2003783885 date "2001-04-01" @default.
• W2003783885 modified "2023-10-18" @default.
• W2003783885 title "Comparison of the effects of intravenous alfentanil and esmolol on the cardiovascular response to double-lumen endobronchial intubation" @default.
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• W2003783885 doi "https://doi.org/10.1046/j.1365-2044.2001.01917.x" @default.
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