FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003803074> ?p ?o ?g. }

• W2003803074 endingPage "S893" @default.
• W2003803074 startingPage "S893" @default.
• W2003803074 abstract "Purpose/Objective(s)Free-breathing and tracking systems are two stereotactic body radiation therapy techniques (SBRT) which can be used for lung treatments. The purpose of this study is to look deeper in the advantages from one technique to the other by a dosimetric parameters comparison.Materials/MethodsFive patients, previously treated using Linac-based SBRT, were selected for this analysis. 4DCT data were acquired for each patient and sorted into 10 phases of breathing cycle such as 0% and 50% phases defined respectively inhalation and exhalation maximum. GTVph, PTVph (= GTVph+3mm) and healthy irradiated lung were contoured on each phase. The prescribed dose was 60Gy in 4 fractions. For tracking technique, 3D conformal SBRT with 9 fields were planned for every phase and were summed. Tracking plans were normalized such as 99% dose covered 99% of PTVph and respected dose constraints of ROSEL study. For free-breathing technique, ITVFB was created from a sum of all GTVph and 3mm margin on ITVFB defined a PTVFB. PTVFB was reported on each respiratory phase images and dose distributions were calculated. The dose normalization and dose constraints were the same as for tracking technique. Finally, 10 plans were summed. This method allowed knowing the dose really received by the GTV (from all GTVph) during a free-breathing irradiation. The 2 modalities were evaluated using dose-volume histograms of each GTVph and PTVph, homogeneity index (HI = (Dmax-Dmin)/Dmean) and the doses to healthy irradiated lung (Dmean and V20Gy).ResultsScientific Abstract 3735; TableDmax (Gy)Dmin (Gy)Dmean (Gy)HIHealthy irradiated lungGTVphPTVphGTVphPTVphGTVphPTVphGTVphPTVphV20Gy (%)Dmean (Gy)Free-breathing82.2868.7657.9277.673.280.170.337.055.4Tracking81.6466.7254.487670.280.20.394.263.84Despite similar maximum doses, free-breathing system improved the target coverage by increasing Dmin and Dmean. Target coverage was slightly more homogeneous with this technique too. On the other hand, the healthy irradiated lung is better protected with tracking technique even if dose constraints were respected in the 2 cases (V20Gy<10%). Open table in a new tab ConclusionsFree-breathing and tracking techniques provide plans with good target coverage and healthy lung protection. While an irradiation with free-breathing increases doses to GTV and PTV, an irradiation with tracking system spares better the healthy lung but can dramatically increase the treatment complexity. Purpose/Objective(s)Free-breathing and tracking systems are two stereotactic body radiation therapy techniques (SBRT) which can be used for lung treatments. The purpose of this study is to look deeper in the advantages from one technique to the other by a dosimetric parameters comparison. Free-breathing and tracking systems are two stereotactic body radiation therapy techniques (SBRT) which can be used for lung treatments. The purpose of this study is to look deeper in the advantages from one technique to the other by a dosimetric parameters comparison. Materials/MethodsFive patients, previously treated using Linac-based SBRT, were selected for this analysis. 4DCT data were acquired for each patient and sorted into 10 phases of breathing cycle such as 0% and 50% phases defined respectively inhalation and exhalation maximum. GTVph, PTVph (= GTVph+3mm) and healthy irradiated lung were contoured on each phase. The prescribed dose was 60Gy in 4 fractions. For tracking technique, 3D conformal SBRT with 9 fields were planned for every phase and were summed. Tracking plans were normalized such as 99% dose covered 99% of PTVph and respected dose constraints of ROSEL study. For free-breathing technique, ITVFB was created from a sum of all GTVph and 3mm margin on ITVFB defined a PTVFB. PTVFB was reported on each respiratory phase images and dose distributions were calculated. The dose normalization and dose constraints were the same as for tracking technique. Finally, 10 plans were summed. This method allowed knowing the dose really received by the GTV (from all GTVph) during a free-breathing irradiation. The 2 modalities were evaluated using dose-volume histograms of each GTVph and PTVph, homogeneity index (HI = (Dmax-Dmin)/Dmean) and the doses to healthy irradiated lung (Dmean and V20Gy). Five patients, previously treated using Linac-based SBRT, were selected for this analysis. 4DCT data were acquired for each patient and sorted into 10 phases of breathing cycle such as 0% and 50% phases defined respectively inhalation and exhalation maximum. GTVph, PTVph (= GTVph+3mm) and healthy irradiated lung were contoured on each phase. The prescribed dose was 60Gy in 4 fractions. For tracking technique, 3D conformal SBRT with 9 fields were planned for every phase and were summed. Tracking plans were normalized such as 99% dose covered 99% of PTVph and respected dose constraints of ROSEL study. For free-breathing technique, ITVFB was created from a sum of all GTVph and 3mm margin on ITVFB defined a PTVFB. PTVFB was reported on each respiratory phase images and dose distributions were calculated. The dose normalization and dose constraints were the same as for tracking technique. Finally, 10 plans were summed. This method allowed knowing the dose really received by the GTV (from all GTVph) during a free-breathing irradiation. The 2 modalities were evaluated using dose-volume histograms of each GTVph and PTVph, homogeneity index (HI = (Dmax-Dmin)/Dmean) and the doses to healthy irradiated lung (Dmean and V20Gy). ResultsScientific Abstract 3735; TableDmax (Gy)Dmin (Gy)Dmean (Gy)HIHealthy irradiated lungGTVphPTVphGTVphPTVphGTVphPTVphGTVphPTVphV20Gy (%)Dmean (Gy)Free-breathing82.2868.7657.9277.673.280.170.337.055.4Tracking81.6466.7254.487670.280.20.394.263.84Despite similar maximum doses, free-breathing system improved the target coverage by increasing Dmin and Dmean. Target coverage was slightly more homogeneous with this technique too. On the other hand, the healthy irradiated lung is better protected with tracking technique even if dose constraints were respected in the 2 cases (V20Gy<10%). Open table in a new tab Despite similar maximum doses, free-breathing system improved the target coverage by increasing Dmin and Dmean. Target coverage was slightly more homogeneous with this technique too. On the other hand, the healthy irradiated lung is better protected with tracking technique even if dose constraints were respected in the 2 cases (V20Gy<10%). ConclusionsFree-breathing and tracking techniques provide plans with good target coverage and healthy lung protection. While an irradiation with free-breathing increases doses to GTV and PTV, an irradiation with tracking system spares better the healthy lung but can dramatically increase the treatment complexity. Free-breathing and tracking techniques provide plans with good target coverage and healthy lung protection. While an irradiation with free-breathing increases doses to GTV and PTV, an irradiation with tracking system spares better the healthy lung but can dramatically increase the treatment complexity." @default.
• W2003803074 created "2016-06-24" @default.
• W2003803074 creator A5031202796 @default.
• W2003803074 creator A5051854092 @default.
• W2003803074 creator A5058256328 @default.
• W2003803074 creator A5062513412 @default.
• W2003803074 creator A5079573063 @default.
• W2003803074 creator A5083326377 @default.
• W2003803074 date "2014-09-01" @default.
• W2003803074 modified "2023-10-10" @default.
• W2003803074 title "Is Tracking Better Than Free Breathing for Lung Stereotactic Treatments?: A Dosimetric Comparison" @default.
• W2003803074 doi "https://doi.org/10.1016/j.ijrobp.2014.05.2543" @default.
• W2003803074 hasPublicationYear "2014" @default.
• W2003803074 type Work @default.
• W2003803074 sameAs 2003803074 @default.
• W2003803074 citedByCount "0" @default.
• W2003803074 crossrefType "journal-article" @default.
• W2003803074 hasAuthorship W2003803074A5031202796 @default.
• W2003803074 hasAuthorship W2003803074A5051854092 @default.
• W2003803074 hasAuthorship W2003803074A5058256328 @default.
• W2003803074 hasAuthorship W2003803074A5062513412 @default.
• W2003803074 hasAuthorship W2003803074A5079573063 @default.
• W2003803074 hasAuthorship W2003803074A5083326377 @default.
• W2003803074 hasBestOaLocation W20038030741 @default.
• W2003803074 hasConcept C126322002 @default.
• W2003803074 hasConcept C126838900 @default.
• W2003803074 hasConcept C15744967 @default.
• W2003803074 hasConcept C19417346 @default.
• W2003803074 hasConcept C19527891 @default.
• W2003803074 hasConcept C2775936607 @default.
• W2003803074 hasConcept C2777714996 @default.
• W2003803074 hasConcept C2780387249 @default.
• W2003803074 hasConcept C2989005 @default.
• W2003803074 hasConcept C2992393070 @default.
• W2003803074 hasConcept C39300077 @default.
• W2003803074 hasConcept C42219234 @default.
• W2003803074 hasConcept C509974204 @default.
• W2003803074 hasConcept C71924100 @default.
• W2003803074 hasConceptScore W2003803074C126322002 @default.
• W2003803074 hasConceptScore W2003803074C126838900 @default.
• W2003803074 hasConceptScore W2003803074C15744967 @default.
• W2003803074 hasConceptScore W2003803074C19417346 @default.
• W2003803074 hasConceptScore W2003803074C19527891 @default.
• W2003803074 hasConceptScore W2003803074C2775936607 @default.
• W2003803074 hasConceptScore W2003803074C2777714996 @default.
• W2003803074 hasConceptScore W2003803074C2780387249 @default.
• W2003803074 hasConceptScore W2003803074C2989005 @default.
• W2003803074 hasConceptScore W2003803074C2992393070 @default.
• W2003803074 hasConceptScore W2003803074C39300077 @default.
• W2003803074 hasConceptScore W2003803074C42219234 @default.
• W2003803074 hasConceptScore W2003803074C509974204 @default.
• W2003803074 hasConceptScore W2003803074C71924100 @default.
• W2003803074 hasIssue "1" @default.
• W2003803074 hasLocation W20038030741 @default.
• W2003803074 hasOpenAccess W2003803074 @default.
• W2003803074 hasPrimaryLocation W20038030741 @default.
• W2003803074 hasRelatedWork W2026946419 @default.
• W2003803074 hasRelatedWork W2034620090 @default.
• W2003803074 hasRelatedWork W2061245727 @default.
• W2003803074 hasRelatedWork W2084539146 @default.
• W2003803074 hasRelatedWork W2109622655 @default.
• W2003803074 hasRelatedWork W2154290239 @default.
• W2003803074 hasRelatedWork W2607200458 @default.
• W2003803074 hasRelatedWork W2810235317 @default.
• W2003803074 hasRelatedWork W3012982787 @default.
• W2003803074 hasRelatedWork W3032745538 @default.
• W2003803074 hasVolume "90" @default.
• W2003803074 isParatext "false" @default.
• W2003803074 isRetracted "false" @default.
• W2003803074 magId "2003803074" @default.
• W2003803074 workType "article" @default.