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- W2003803323 abstract "1. Exposure of mouse DNA-dependent RNA polymerase I and II to 1 × 10−5 M hematoporphyrin and visible light (6328 Å) caused extensive enzyme inactivation. 1 × 10−4M hematoporphyrin inactivated RNA polymerase I and II in the absence of light. 2. Exposure of both RNA polymerase I and II to visible light in the absence of hematoporphyrin caused no detectable inactivation during the course of the experiment. 3. Increasing concentrations of dithiothreitol caused decreased inactivation of both enzymes. 4. Exposure of template DNA to conditions identical to those which caused extensive enzyme inactivation resulted in no significant changes in viscosity and no changes in template activity for the RNA polymerases." @default.
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- W2003803323 title "Photodynamic inactivation of mammalian dna-dependent rna polymerase by hematoporphyrin and visible light" @default.
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- W2003803323 doi "https://doi.org/10.1016/0020-711x(79)90074-0" @default.
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