FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003847333> ?p ?o ?g. }

• W2003847333 endingPage "62" @default.
• W2003847333 startingPage "54" @default.
• W2003847333 abstract "To assess developmental characteristics of nociceptive responses induced by bee venom (BV) injection in neonatal rats, we exposed pups to intra-plantar injection of various BV concentrations given at different time points between postnatal day 1 and day 28 (P1-P28). Persistent spontaneous nociception (PSN) as well as thermal and mechanical nociceptive response was compared before and after a BV injection. There were distinct age-related changes in the baseline paw withdrawal thermal latency (PWTL) and paw withdrawal mechanical threshold (PWMT) when examined on P1, P4, P7, P14, P21, and P28. The lowest and highest baseline PWTL was shown on P1 and P7, respectively, and PWTL was unchanged from P7 to P28. In contrast, the baseline PWMT remained low before P21 but increased dramatically afterward. Neonatal rats receiving intra-plantar BV injection showed a time-dependent change in nociceptive responses, including (1) a dose-related increase in PSN from P1 to P28; (2) a non-specific decrease (indistinguishable between saline and BV injection) in PWTL and PWMT up to P14 and P21, respectively; and (3) a specific decrease (in response to BV injection only) in PWTL and PWMT after P14 and P21, respectively. These findings indicate that characteristic changes in the baseline and BV-induced nociceptive response are both time-dependent and modality-specific in neonatal rats. The data reveal a critical postnatal period during which nociceptive stimulation could have a significant influence on nociceptive behavior in adult rats and suggest that preclinical models of neonatal nociception should be evaluated according to different postnatal time points." @default.
• W2003847333 created "2016-06-24" @default.
• W2003847333 creator A5004846643 @default.
• W2003847333 creator A5019324414 @default.
• W2003847333 creator A5027386872 @default.
• W2003847333 creator A5070578002 @default.
• W2003847333 creator A5078623648 @default.
• W2003847333 creator A5081960363 @default.
• W2003847333 date "2012-09-01" @default.
• W2003847333 modified "2023-10-18" @default.
• W2003847333 title "Characterization of nociceptive responses to bee venom-induced inflammation in neonatal rats" @default.
• W2003847333 cites W1548172758 @default.
• W2003847333 cites W1562045417 @default.
• W2003847333 cites W1587444494 @default.
• W2003847333 cites W1919014346 @default.
• W2003847333 cites W1966756130 @default.
• W2003847333 cites W1969439040 @default.
• W2003847333 cites W1970879958 @default.
• W2003847333 cites W1974334539 @default.
• W2003847333 cites W1978271409 @default.
• W2003847333 cites W1982879980 @default.
• W2003847333 cites W1984760139 @default.
• W2003847333 cites W1985795242 @default.
• W2003847333 cites W1988230248 @default.
• W2003847333 cites W1990986143 @default.
• W2003847333 cites W1992624389 @default.
• W2003847333 cites W1995963044 @default.
• W2003847333 cites W1998151383 @default.
• W2003847333 cites W2001933690 @default.
• W2003847333 cites W2011540368 @default.
• W2003847333 cites W2016718112 @default.
• W2003847333 cites W2019082225 @default.
• W2003847333 cites W2019208784 @default.
• W2003847333 cites W2022029970 @default.
• W2003847333 cites W2034953779 @default.
• W2003847333 cites W2035523490 @default.
• W2003847333 cites W2037048763 @default.
• W2003847333 cites W2042247566 @default.
• W2003847333 cites W2044686423 @default.
• W2003847333 cites W2045217336 @default.
• W2003847333 cites W2045804560 @default.
• W2003847333 cites W2053105573 @default.
• W2003847333 cites W2059477631 @default.
• W2003847333 cites W2061132063 @default.
• W2003847333 cites W2063170472 @default.
• W2003847333 cites W2069645475 @default.
• W2003847333 cites W2079226821 @default.
• W2003847333 cites W2080076872 @default.
• W2003847333 cites W2080113500 @default.
• W2003847333 cites W2081227041 @default.
• W2003847333 cites W2082477901 @default.
• W2003847333 cites W2087454739 @default.
• W2003847333 cites W2106781193 @default.
• W2003847333 cites W2114455248 @default.
• W2003847333 cites W2128025865 @default.
• W2003847333 cites W2136999245 @default.
• W2003847333 cites W2156791971 @default.
• W2003847333 cites W2157863430 @default.
• W2003847333 cites W2158380688 @default.
• W2003847333 cites W2410912771 @default.
• W2003847333 doi "https://doi.org/10.1016/j.brainres.2012.07.005" @default.
• W2003847333 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22800806" @default.
• W2003847333 hasPublicationYear "2012" @default.
• W2003847333 type Work @default.
• W2003847333 sameAs 2003847333 @default.
• W2003847333 citedByCount "4" @default.
• W2003847333 countsByYear W20038473332014 @default.
• W2003847333 countsByYear W20038473332016 @default.
• W2003847333 countsByYear W20038473332018 @default.
• W2003847333 crossrefType "journal-article" @default.
• W2003847333 hasAuthorship W2003847333A5004846643 @default.
• W2003847333 hasAuthorship W2003847333A5019324414 @default.
• W2003847333 hasAuthorship W2003847333A5027386872 @default.
• W2003847333 hasAuthorship W2003847333A5070578002 @default.
• W2003847333 hasAuthorship W2003847333A5078623648 @default.
• W2003847333 hasAuthorship W2003847333A5081960363 @default.
• W2003847333 hasConcept C126322002 @default.
• W2003847333 hasConcept C134018914 @default.
• W2003847333 hasConcept C15490471 @default.
• W2003847333 hasConcept C170493617 @default.
• W2003847333 hasConcept C24998067 @default.
• W2003847333 hasConcept C2777397205 @default.
• W2003847333 hasConcept C42219234 @default.
• W2003847333 hasConcept C71924100 @default.
• W2003847333 hasConceptScore W2003847333C126322002 @default.
• W2003847333 hasConceptScore W2003847333C134018914 @default.
• W2003847333 hasConceptScore W2003847333C15490471 @default.
• W2003847333 hasConceptScore W2003847333C170493617 @default.
• W2003847333 hasConceptScore W2003847333C24998067 @default.
• W2003847333 hasConceptScore W2003847333C2777397205 @default.
• W2003847333 hasConceptScore W2003847333C42219234 @default.
• W2003847333 hasConceptScore W2003847333C71924100 @default.
• W2003847333 hasFunder F4320321001 @default.
• W2003847333 hasFunder F4320322919 @default.
• W2003847333 hasLocation W20038473331 @default.
• W2003847333 hasLocation W20038473332 @default.
• W2003847333 hasOpenAccess W2003847333 @default.
• W2003847333 hasPrimaryLocation W20038473331 @default.

• next