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- W2003865982 abstract "It has recently become clear that cyclin-dependent kinase (cdk) complex regulates the cell cycle by phosphorylating Rb protein, a tumor suppressor protein. It is likely that this complex is a target of various growth factors and anti-growth factors (UV, TGF-beta etc.) in keratinocyte (KC). It has also been suggested that abnormalities in the cell cycle regulating mechanism such as increased activity of cyclin-cdk due to mutation of p53, a tumor suppressor gene, and overexpression of cyclin D may be concerned with carcinogenesis of KC. Thus, recent studies indicate that the cyclin-cdk complex is a common target of proliferation and carcinogenesis in KC." @default.
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- W2003865982 date "1995-02-01" @default.
- W2003865982 modified "2023-10-02" @default.
- W2003865982 title "Cell cycle regulators in the keratinocyte (cyclin-cdk)" @default.
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- W2003865982 doi "https://doi.org/10.1111/j.1600-0625.1995.tb00215.x" @default.
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