Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003891653> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W2003891653 endingPage "852" @default.
- W2003891653 startingPage "848" @default.
- W2003891653 abstract "Teboroxime, a new technetium-99m-labeled myocardial perfusion tracer, possesses rapid myocardial kinetics. Whereas this agent is routinely imaged after separate stress and rest injections, experimental data suggest that teboroxime may rapidly redistribute in the myocardium. Accordingly, we assessed 68 exercise teboroxime scintigrams in which immediate poststress, early delay (5 minutes) and rest images were acquired. Studies were categorized visually as ischemia, infarct or normal based on conventional stress-rest comparison. They were then evaluated for rapid teboroxime redistribution by comparing the stress and early delay images. Quantitative analysis was then performed on 537 myocardial segments. Segments were grouped as ischemia, infarct or normal based on stress-rest comparison, and the degree of normalization of stress-induced defects in the early delay images was determined for each group. Rapid teboroxime redistribution was observed in 20 of 46 scintigrams (48%) considered ischemic, and in 2 of 7 and 2 of 15 scintigrams deemed infarct and normal, respectively. The mean segmental intensity ratio (defined relative to the opposite segment) improved from 0.79 at stress to 0.88 at early delay (p < 0.005) in the group with ischemia and from 0.83 to 0.87 in the group with infarction. The most likely explanation for rapid redistribution of teboroxime is differential washout from the myocardium between areas of disparate flow. It is concluded that rapid redistribution of teboroxime occurs within 5 minutes of a stress injection, giving rise to potentially useful clinical information. Thus, teboroxime imaging should be completed expeditiously to detect areas of relative hypoperfusion." @default.
- W2003891653 created "2016-06-24" @default.
- W2003891653 creator A5005058224 @default.
- W2003891653 creator A5035798322 @default.
- W2003891653 creator A5047574519 @default.
- W2003891653 creator A5067977702 @default.
- W2003891653 creator A5091123456 @default.
- W2003891653 date "1993-04-01" @default.
- W2003891653 modified "2023-09-25" @default.
- W2003891653 title "Rapid redistribution of teboroxime" @default.
- W2003891653 cites W1845324092 @default.
- W2003891653 cites W1904207040 @default.
- W2003891653 cites W1912935968 @default.
- W2003891653 cites W1979140957 @default.
- W2003891653 cites W1985865925 @default.
- W2003891653 cites W2019126485 @default.
- W2003891653 cites W2062328089 @default.
- W2003891653 cites W2076871795 @default.
- W2003891653 cites W2113133543 @default.
- W2003891653 cites W2139160364 @default.
- W2003891653 cites W2186422146 @default.
- W2003891653 cites W2291863174 @default.
- W2003891653 cites W2412782191 @default.
- W2003891653 doi "https://doi.org/10.1016/0002-9149(93)90835-z" @default.
- W2003891653 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8456765" @default.
- W2003891653 hasPublicationYear "1993" @default.
- W2003891653 type Work @default.
- W2003891653 sameAs 2003891653 @default.
- W2003891653 citedByCount "10" @default.
- W2003891653 countsByYear W20038916532014 @default.
- W2003891653 countsByYear W20038916532020 @default.
- W2003891653 countsByYear W20038916532022 @default.
- W2003891653 crossrefType "journal-article" @default.
- W2003891653 hasAuthorship W2003891653A5005058224 @default.
- W2003891653 hasAuthorship W2003891653A5035798322 @default.
- W2003891653 hasAuthorship W2003891653A5047574519 @default.
- W2003891653 hasAuthorship W2003891653A5067977702 @default.
- W2003891653 hasAuthorship W2003891653A5091123456 @default.
- W2003891653 hasConcept C126322002 @default.
- W2003891653 hasConcept C146957229 @default.
- W2003891653 hasConcept C164705383 @default.
- W2003891653 hasConcept C199360897 @default.
- W2003891653 hasConcept C2777798775 @default.
- W2003891653 hasConcept C2779902710 @default.
- W2003891653 hasConcept C2989005 @default.
- W2003891653 hasConcept C41008148 @default.
- W2003891653 hasConcept C500558357 @default.
- W2003891653 hasConcept C541997718 @default.
- W2003891653 hasConcept C71924100 @default.
- W2003891653 hasConcept C7515471 @default.
- W2003891653 hasConceptScore W2003891653C126322002 @default.
- W2003891653 hasConceptScore W2003891653C146957229 @default.
- W2003891653 hasConceptScore W2003891653C164705383 @default.
- W2003891653 hasConceptScore W2003891653C199360897 @default.
- W2003891653 hasConceptScore W2003891653C2777798775 @default.
- W2003891653 hasConceptScore W2003891653C2779902710 @default.
- W2003891653 hasConceptScore W2003891653C2989005 @default.
- W2003891653 hasConceptScore W2003891653C41008148 @default.
- W2003891653 hasConceptScore W2003891653C500558357 @default.
- W2003891653 hasConceptScore W2003891653C541997718 @default.
- W2003891653 hasConceptScore W2003891653C71924100 @default.
- W2003891653 hasConceptScore W2003891653C7515471 @default.
- W2003891653 hasIssue "10" @default.
- W2003891653 hasLocation W20038916531 @default.
- W2003891653 hasLocation W20038916532 @default.
- W2003891653 hasOpenAccess W2003891653 @default.
- W2003891653 hasPrimaryLocation W20038916531 @default.
- W2003891653 hasRelatedWork W1497823195 @default.
- W2003891653 hasRelatedWork W2008851126 @default.
- W2003891653 hasRelatedWork W2015763030 @default.
- W2003891653 hasRelatedWork W2028222475 @default.
- W2003891653 hasRelatedWork W2049397185 @default.
- W2003891653 hasRelatedWork W2093502227 @default.
- W2003891653 hasRelatedWork W2371846023 @default.
- W2003891653 hasRelatedWork W2399063111 @default.
- W2003891653 hasRelatedWork W2417928660 @default.
- W2003891653 hasRelatedWork W2130232188 @default.
- W2003891653 hasVolume "71" @default.
- W2003891653 isParatext "false" @default.
- W2003891653 isRetracted "false" @default.
- W2003891653 magId "2003891653" @default.
- W2003891653 workType "article" @default.