Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003896274> ?p ?o ?g. }
Showing items 1 to 68 of
68
with 100 items per page.
- W2003896274 abstract "Strips of canine saphenous vein, inferior vena cava, and femoral artery were studied isometrically in vitro to compare quantitatively the alpha 1- and postsynaptic alpha 2-adrenoceptor contributions to the contractile force generated by l-norepinephrine (NE). Effects mediated by each receptor type were measured independently by quantitative blockade of virtually all alpha 1-receptors with prazosin, or alpha 2-receptors with rauwolscine. Appropriate concentrations of the antagonists were calculated from dissociation constants previously determined by binding or competition with [3H]prazosin or [3H]rauwolscine in tissue homogenates. The contribution of alpha 1-adrenoceptors was larger than that of alpha 2-receptors in all vessels. The alpha 2-type was responsible for 38% of the maximum unblocked response to NE in saphenous vein, 32% in vena cava, and 28% in femoral artery. The occupation-response relationship for alpha 1-receptors was almost linear, without the marked upward convexity reported in some other vessels. alpha 2-Occupation-response curves were convex towards the occupation axis, with a relatively small response at low levels of occupation." @default.
- W2003896274 created "2016-06-24" @default.
- W2003896274 creator A5048288174 @default.
- W2003896274 creator A5056591460 @default.
- W2003896274 creator A5085767006 @default.
- W2003896274 date "1988-01-01" @default.
- W2003896274 modified "2023-09-27" @default.
- W2003896274 title "Contributions of Alpha<sub>1</sub> and Alpha<sub>2</sub>-Adrenoceptors to Contractile Response in Canine Blood Vessels" @default.
- W2003896274 doi "https://doi.org/10.1159/000158732" @default.
- W2003896274 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2839257" @default.
- W2003896274 hasPublicationYear "1988" @default.
- W2003896274 type Work @default.
- W2003896274 sameAs 2003896274 @default.
- W2003896274 citedByCount "2" @default.
- W2003896274 crossrefType "journal-article" @default.
- W2003896274 hasAuthorship W2003896274A5048288174 @default.
- W2003896274 hasAuthorship W2003896274A5056591460 @default.
- W2003896274 hasAuthorship W2003896274A5085767006 @default.
- W2003896274 hasConcept C105702510 @default.
- W2003896274 hasConcept C126322002 @default.
- W2003896274 hasConcept C13348194 @default.
- W2003896274 hasConcept C134018914 @default.
- W2003896274 hasConcept C141071460 @default.
- W2003896274 hasConcept C170493617 @default.
- W2003896274 hasConcept C185592680 @default.
- W2003896274 hasConcept C2775944032 @default.
- W2003896274 hasConcept C2776504411 @default.
- W2003896274 hasConcept C2776885963 @default.
- W2003896274 hasConcept C2777663904 @default.
- W2003896274 hasConcept C2780648677 @default.
- W2003896274 hasConcept C49453240 @default.
- W2003896274 hasConcept C64943373 @default.
- W2003896274 hasConcept C71924100 @default.
- W2003896274 hasConcept C86803240 @default.
- W2003896274 hasConceptScore W2003896274C105702510 @default.
- W2003896274 hasConceptScore W2003896274C126322002 @default.
- W2003896274 hasConceptScore W2003896274C13348194 @default.
- W2003896274 hasConceptScore W2003896274C134018914 @default.
- W2003896274 hasConceptScore W2003896274C141071460 @default.
- W2003896274 hasConceptScore W2003896274C170493617 @default.
- W2003896274 hasConceptScore W2003896274C185592680 @default.
- W2003896274 hasConceptScore W2003896274C2775944032 @default.
- W2003896274 hasConceptScore W2003896274C2776504411 @default.
- W2003896274 hasConceptScore W2003896274C2776885963 @default.
- W2003896274 hasConceptScore W2003896274C2777663904 @default.
- W2003896274 hasConceptScore W2003896274C2780648677 @default.
- W2003896274 hasConceptScore W2003896274C49453240 @default.
- W2003896274 hasConceptScore W2003896274C64943373 @default.
- W2003896274 hasConceptScore W2003896274C71924100 @default.
- W2003896274 hasConceptScore W2003896274C86803240 @default.
- W2003896274 hasLocation W20038962741 @default.
- W2003896274 hasLocation W20038962742 @default.
- W2003896274 hasOpenAccess W2003896274 @default.
- W2003896274 hasPrimaryLocation W20038962741 @default.
- W2003896274 hasRelatedWork W1983321239 @default.
- W2003896274 hasRelatedWork W1990829367 @default.
- W2003896274 hasRelatedWork W1995970717 @default.
- W2003896274 hasRelatedWork W2008170529 @default.
- W2003896274 hasRelatedWork W2062311706 @default.
- W2003896274 hasRelatedWork W2070845189 @default.
- W2003896274 hasRelatedWork W2239310254 @default.
- W2003896274 hasRelatedWork W2318367145 @default.
- W2003896274 hasRelatedWork W2400916215 @default.
- W2003896274 hasRelatedWork W2419483295 @default.
- W2003896274 isParatext "false" @default.
- W2003896274 isRetracted "false" @default.
- W2003896274 magId "2003896274" @default.
- W2003896274 workType "article" @default.