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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003904213> ?p ?o ?g. }

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• W2003904213 abstract "Herein we report the discovery, synthesis, and evaluation of a series of N-(4-acetamido)-phenylpicolinamides as positive allosteric modulators of mGlu(4). Compounds from the series show submicromolar potency at both human and rat mGlu(4). In addition, pharmacokinetic studies utilizing subcutaneous dosing demonstrated good brain exposure in rats." @default.
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• W2003904213 date "2011-01-19" @default.
• W2003904213 modified "2023-10-14" @default.
• W2003904213 title "Discovery, Synthesis, and Structure−Activity Relationship Development of a Series of <i>N</i>-(4-Acetamido)phenylpicolinamides as Positive Allosteric Modulators of Metabotropic Glutamate Receptor 4 (mGlu₄) with CNS Exposure in Rats" @default.
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• W2003904213 doi "https://doi.org/10.1021/jm101271s" @default.
• W2003904213 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3166797" @default.
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