Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003924932> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W2003924932 endingPage "937" @default.
- W2003924932 startingPage "932" @default.
- W2003924932 abstract "Proteasomes play a key role in the degradation of abnormal proteins, of short-lived regulatory proteins and in antigen processing. Evidence is accumulating that the 20 S proteasome represents the proteolytic core of the 26 S protease complex (26 S proteasome) which contains several additional subunits implicated in regulation and substrate recognition. Using electron microscopy and digital image analysis we obtained first insights into the structure of this complex which has an estimated molecular weight of approximately 2000 kDa. Two highly asymmetric masses which presumably contain the regulatory subunits of the 26 S complex are attached to both ends of the dimeric 20 S proteasome clearly reflecting its C2 symmetry. The structural uniformity of the complex, i.e. the absence of significant inter-image variations, has important implications for the structure of the latter: It indicates that, in spite of their sequence similarities, the various alpha-type and beta-type subunits of the 20 S proteasome are not promiscuous but occupy precisely defined positions." @default.
- W2003924932 created "2016-06-24" @default.
- W2003924932 creator A5022934794 @default.
- W2003924932 creator A5029559203 @default.
- W2003924932 creator A5055191083 @default.
- W2003924932 creator A5059766769 @default.
- W2003924932 creator A5063194678 @default.
- W2003924932 date "1993-12-01" @default.
- W2003924932 modified "2023-10-17" @default.
- W2003924932 title "Structural Features of the 26 S Proteasome Complex" @default.
- W2003924932 doi "https://doi.org/10.1006/jmbi.1993.1646" @default.
- W2003924932 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8263938" @default.
- W2003924932 hasPublicationYear "1993" @default.
- W2003924932 type Work @default.
- W2003924932 sameAs 2003924932 @default.
- W2003924932 citedByCount "245" @default.
- W2003924932 countsByYear W20039249322012 @default.
- W2003924932 countsByYear W20039249322013 @default.
- W2003924932 countsByYear W20039249322014 @default.
- W2003924932 countsByYear W20039249322015 @default.
- W2003924932 countsByYear W20039249322016 @default.
- W2003924932 countsByYear W20039249322017 @default.
- W2003924932 countsByYear W20039249322018 @default.
- W2003924932 countsByYear W20039249322019 @default.
- W2003924932 countsByYear W20039249322020 @default.
- W2003924932 countsByYear W20039249322021 @default.
- W2003924932 countsByYear W20039249322023 @default.
- W2003924932 crossrefType "journal-article" @default.
- W2003924932 hasAuthorship W2003924932A5022934794 @default.
- W2003924932 hasAuthorship W2003924932A5029559203 @default.
- W2003924932 hasAuthorship W2003924932A5055191083 @default.
- W2003924932 hasAuthorship W2003924932A5059766769 @default.
- W2003924932 hasAuthorship W2003924932A5063194678 @default.
- W2003924932 hasConcept C104292427 @default.
- W2003924932 hasConcept C104317684 @default.
- W2003924932 hasConcept C12554922 @default.
- W2003924932 hasConcept C181199279 @default.
- W2003924932 hasConcept C185592680 @default.
- W2003924932 hasConcept C27740335 @default.
- W2003924932 hasConcept C2776714187 @default.
- W2003924932 hasConcept C2781307694 @default.
- W2003924932 hasConcept C2992195973 @default.
- W2003924932 hasConcept C55493867 @default.
- W2003924932 hasConcept C70721500 @default.
- W2003924932 hasConcept C8010536 @default.
- W2003924932 hasConcept C86803240 @default.
- W2003924932 hasConcept C95444343 @default.
- W2003924932 hasConceptScore W2003924932C104292427 @default.
- W2003924932 hasConceptScore W2003924932C104317684 @default.
- W2003924932 hasConceptScore W2003924932C12554922 @default.
- W2003924932 hasConceptScore W2003924932C181199279 @default.
- W2003924932 hasConceptScore W2003924932C185592680 @default.
- W2003924932 hasConceptScore W2003924932C27740335 @default.
- W2003924932 hasConceptScore W2003924932C2776714187 @default.
- W2003924932 hasConceptScore W2003924932C2781307694 @default.
- W2003924932 hasConceptScore W2003924932C2992195973 @default.
- W2003924932 hasConceptScore W2003924932C55493867 @default.
- W2003924932 hasConceptScore W2003924932C70721500 @default.
- W2003924932 hasConceptScore W2003924932C8010536 @default.
- W2003924932 hasConceptScore W2003924932C86803240 @default.
- W2003924932 hasConceptScore W2003924932C95444343 @default.
- W2003924932 hasIssue "4" @default.
- W2003924932 hasLocation W20039249321 @default.
- W2003924932 hasLocation W20039249322 @default.
- W2003924932 hasOpenAccess W2003924932 @default.
- W2003924932 hasPrimaryLocation W20039249321 @default.
- W2003924932 hasRelatedWork W1521361692 @default.
- W2003924932 hasRelatedWork W1999823311 @default.
- W2003924932 hasRelatedWork W2051335601 @default.
- W2003924932 hasRelatedWork W2052908468 @default.
- W2003924932 hasRelatedWork W2067156769 @default.
- W2003924932 hasRelatedWork W2067788866 @default.
- W2003924932 hasRelatedWork W2104084141 @default.
- W2003924932 hasRelatedWork W2429296518 @default.
- W2003924932 hasRelatedWork W3102935653 @default.
- W2003924932 hasRelatedWork W4250379661 @default.
- W2003924932 hasVolume "234" @default.
- W2003924932 isParatext "false" @default.
- W2003924932 isRetracted "false" @default.
- W2003924932 magId "2003924932" @default.
- W2003924932 workType "article" @default.