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- W2003965278 abstract "Numerous articles and commentaries in the health literature recently have questioned the emergence of race as an increasingly powerful organizing principle in clinical medicine and pharmaceutical development [ 1 Braun L. et al. Racial categories in medical practice: how useful are they?. PLoS Med. 2007; 4: e271https://doi.org/10.1371/journal.pmed.0040271http://medicine.plosjournals.org Crossref PubMed Scopus (151) Google Scholar , 2 Lee S.S. Racializing drug design: implications of pharmacogenomics for health disparities. Am. J. Public Health. 2005; 95: 2133-2138 Crossref PubMed Scopus (87) Google Scholar ]. Yet proposals for regulatory reform remain thin. Debate over race-based medicine crystallized around the FDA's June 2005 approval of BiDil, a drug approved to treat African-Americans with heart failure. Some saw BiDil as a dangerous example of marketing trumping science [ 3 Kahn J. How a drug becomes ethnic: law, commerce, and the production of racial categories in medicine. Yale J. Health Policy Law Ethics. 2004; 4: 1-46 PubMed Google Scholar ], whereas others heralded BiDil as a step towards eliminating racial disparities in health care [ 4 Puckrein G. BiDil: from another vantage point. Health Aff. 2006; https://doi.org/10.1377/hlthaff.25.w368http://healthaffairs.org Crossref Scopus (18) Google Scholar ]. One thing is clear: the BiDil debate has left major questions about how clinical trial design and drug regulation should engage this trend [ 5 Temple R. Stockbridge N.L. BiDil for heart failure in black patients: The U.S. Food and Drug Administration perspective. Ann. Intern. Med. 2007; 146: 57-61 Crossref PubMed Scopus (88) Google Scholar ]." @default.
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- W2003965278 date "2008-06-01" @default.
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- W2003965278 title "Race-specific drugs: regulatory trends and public policy" @default.
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- W2003965278 doi "https://doi.org/10.1016/j.tips.2008.03.008" @default.
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