Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003993002> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2003993002 endingPage "11" @default.
- W2003993002 startingPage "3" @default.
- W2003993002 abstract "Oral bisphosphonates are first-line therapy for the prevention and treatment of osteoporosis in postmenopausal women. Although bisphosphonate treatment has been shown to reduce fractures in randomized, controlled trials, the number of women treated and fractures prevented over the years have not been determined. This study estimated the numbers of women treated and fractures reduced with oral bisphosphonates in the United States from 2001 through 2008. Two medical claims databases for 2001–2008 were combined to determine numbers of women aged 45 years and older filling prescriptions for bisphosphonates by time-dependent medication possession ratios (MPRs): <50%, 50% to 79%, and ≥80%. Fracture incidence was compared for each cohort by MPR category relative to the referent cohort with <50% MPR. Fracture rates were extrapolated to the US female population treated with oral bisphosphonates by MPR category over this 8-year period. From 2001 through 2008, 460,584 women in the databases initiated treatment with oral bisphosphonates, with an average follow-up time of 2.4 years. Overall fracture rates declined with improved MPR from 1.52% for the lowest MPR category to 1.18% for the highest MPR category for ages 45 to 64 years and from 5.12% to 3.75% for those aged 65 years or older. Extrapolating to the US population of female bisphosphonate users, we estimate over 27.9 million person-years of bisphosphonate treatment with MPR 50% or greater and 144,670 fractures prevented. Treatment with oral bisphosphonates has prevented a substantial number of fractures. Even more fractures would have been prevented if recognition, treatment, and compliance were improved. © 2011 American Society for Bone and Mineral Research." @default.
- W2003993002 created "2016-06-24" @default.
- W2003993002 creator A5013956632 @default.
- W2003993002 creator A5045663774 @default.
- W2003993002 creator A5082138574 @default.
- W2003993002 creator A5090665248 @default.
- W2003993002 date "2010-07-26" @default.
- W2003993002 modified "2023-09-26" @default.
- W2003993002 title "Estimating bisphosphonate use and fracture reduction among US women aged 45 years and older, 2001-2008" @default.
- W2003993002 cites W1978677270 @default.
- W2003993002 cites W1979344569 @default.
- W2003993002 cites W2012596468 @default.
- W2003993002 cites W2019859066 @default.
- W2003993002 cites W2021278303 @default.
- W2003993002 cites W2022343568 @default.
- W2003993002 cites W2032093049 @default.
- W2003993002 cites W2048541373 @default.
- W2003993002 cites W2091958823 @default.
- W2003993002 cites W2094819865 @default.
- W2003993002 cites W2099054178 @default.
- W2003993002 cites W2116705247 @default.
- W2003993002 cites W2124527463 @default.
- W2003993002 cites W2139062201 @default.
- W2003993002 cites W4254234396 @default.
- W2003993002 doi "https://doi.org/10.1002/jbmr.189" @default.
- W2003993002 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20662073" @default.
- W2003993002 hasPublicationYear "2010" @default.
- W2003993002 type Work @default.
- W2003993002 sameAs 2003993002 @default.
- W2003993002 citedByCount "78" @default.
- W2003993002 countsByYear W20039930022012 @default.
- W2003993002 countsByYear W20039930022013 @default.
- W2003993002 countsByYear W20039930022014 @default.
- W2003993002 countsByYear W20039930022015 @default.
- W2003993002 countsByYear W20039930022016 @default.
- W2003993002 countsByYear W20039930022017 @default.
- W2003993002 countsByYear W20039930022018 @default.
- W2003993002 countsByYear W20039930022019 @default.
- W2003993002 countsByYear W20039930022020 @default.
- W2003993002 countsByYear W20039930022021 @default.
- W2003993002 countsByYear W20039930022022 @default.
- W2003993002 countsByYear W20039930022023 @default.
- W2003993002 crossrefType "journal-article" @default.
- W2003993002 hasAuthorship W2003993002A5013956632 @default.
- W2003993002 hasAuthorship W2003993002A5045663774 @default.
- W2003993002 hasAuthorship W2003993002A5082138574 @default.
- W2003993002 hasAuthorship W2003993002A5090665248 @default.
- W2003993002 hasBestOaLocation W20039930021 @default.
- W2003993002 hasConcept C120665830 @default.
- W2003993002 hasConcept C121332964 @default.
- W2003993002 hasConcept C126322002 @default.
- W2003993002 hasConcept C187212893 @default.
- W2003993002 hasConcept C199343813 @default.
- W2003993002 hasConcept C2426938 @default.
- W2003993002 hasConcept C2776541429 @default.
- W2003993002 hasConcept C2777251235 @default.
- W2003993002 hasConcept C2778885795 @default.
- W2003993002 hasConcept C2908647359 @default.
- W2003993002 hasConcept C61511704 @default.
- W2003993002 hasConcept C71924100 @default.
- W2003993002 hasConcept C72563966 @default.
- W2003993002 hasConcept C98274493 @default.
- W2003993002 hasConcept C99454951 @default.
- W2003993002 hasConceptScore W2003993002C120665830 @default.
- W2003993002 hasConceptScore W2003993002C121332964 @default.
- W2003993002 hasConceptScore W2003993002C126322002 @default.
- W2003993002 hasConceptScore W2003993002C187212893 @default.
- W2003993002 hasConceptScore W2003993002C199343813 @default.
- W2003993002 hasConceptScore W2003993002C2426938 @default.
- W2003993002 hasConceptScore W2003993002C2776541429 @default.
- W2003993002 hasConceptScore W2003993002C2777251235 @default.
- W2003993002 hasConceptScore W2003993002C2778885795 @default.
- W2003993002 hasConceptScore W2003993002C2908647359 @default.
- W2003993002 hasConceptScore W2003993002C61511704 @default.
- W2003993002 hasConceptScore W2003993002C71924100 @default.
- W2003993002 hasConceptScore W2003993002C72563966 @default.
- W2003993002 hasConceptScore W2003993002C98274493 @default.
- W2003993002 hasConceptScore W2003993002C99454951 @default.
- W2003993002 hasIssue "1" @default.
- W2003993002 hasLocation W20039930021 @default.
- W2003993002 hasLocation W20039930022 @default.
- W2003993002 hasOpenAccess W2003993002 @default.
- W2003993002 hasPrimaryLocation W20039930021 @default.
- W2003993002 hasRelatedWork W2023544965 @default.
- W2003993002 hasRelatedWork W2045787805 @default.
- W2003993002 hasRelatedWork W2056489738 @default.
- W2003993002 hasRelatedWork W2139692423 @default.
- W2003993002 hasRelatedWork W2186551990 @default.
- W2003993002 hasRelatedWork W2399635335 @default.
- W2003993002 hasRelatedWork W2403631838 @default.
- W2003993002 hasRelatedWork W2559914334 @default.
- W2003993002 hasRelatedWork W2617255097 @default.
- W2003993002 hasRelatedWork W4292295546 @default.
- W2003993002 hasVolume "26" @default.
- W2003993002 isParatext "false" @default.
- W2003993002 isRetracted "false" @default.
- W2003993002 magId "2003993002" @default.
- W2003993002 workType "article" @default.